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Coordinates with Cancer Immunology, Protein Chemistry, Antibody Engineering, and Translational Oncology groups to advance lead molecules of the projects. Familiarity with automated or semi-automated instrumentation, while not required, would be advantageous, as would familiarity with the multi-disciplinary activities of antibody lead profiling.
ExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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Serve as DMPK and BA representative on project teams supporting the development of novel drug candidates (small molecules, possibly biologics and antibody drug conjugates) for the treatment of diseases in Oncology, and Immuno-Oncology.
$129,500 - $191,500 a yearFull-timeExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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Serve as scientific team member conducting routine analysis of biotherapeutics in antibody discovery projects. Job Summary We are seeking a Research Scientist II - Biosensor for our Discovery site located in South San Francisco, CA.
ExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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First-hand knowledge of and experience with assays relevant for cell therapies including flow cytometry, IHC, qPCR, anti-therapeutic antibody assessment, T-cell antigen specific response assays (ELISPOT, flow based, tetramer, etc.
ExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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The ideal candidate will have expertise in protein engineering techniques, including phage, yeast, or mammalian cell display, experience optimizing expression and purification of antibody fragments (e.g. minibody and Fc-fusions) and have a working knowledge of antibody structure and function.
$122,000 - $168,000 a yearFull-timeExpandUpdated 6 days ago - UpvoteDownvoteShare Job
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The Associate Director of Supply Chain will be accountable for building the clinical supply and demand planning processes, managing clinical orders and providing oversight for logistics providers throughout the development stages of antibody-based radiopharmaceuticals.
ExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Experience of biomarker discovery and translational research in at least some of the following areas: (i) immunotherapy or (ii) targeted therapies such as antibody-drug conjugates, and small molecule target therapy et al.
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He/she will also be accountable for developing membrane protein target-expressing cell lines to support Protein Therapeutics' internal antibody discovery and screening activities. ResponsibilitiesExpand research cell line generation function to support antibody discovery activities from target expression, candidate production, and screening cell line engineeringServe as subject matter expert in cell line engineering technologies.
$191,335 - $247,610ExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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FibroGen recently expanded its research and development portfolio to include antibody-drug conjugate (ADC) and immuno-oncology product candidates for the treatment of solid tumors. Pamrevlumab, an anti-CTGF fully human monoclonal antibody, is in clinical development for the treatment of metastatic pancreatic cancer and locally advanced unresectable pancreatic cancer (LAPC.
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Experience developing and working with various antibody discovery and protein engineering technologies such as mouse hybridoma, single B cell, phage/yeast/mammalian display, and/or computer-aided antibody/protein design is required.
ExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Implements, optimizes and performs immunochemical, biochemical and cellular assays to characterize binding, potency, pharmacokinetics and mechanism of action of antibody candidates. Supports therapeutic antibody discovery projects related to Cancer-Immunology, Oncology as well as Ocular diseases.
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Understanding of bioanalytical techniques and methods for measuring drug levels and anti-drug antibody responses. Capable of independently authoring and delivering ADME and Clinical Pharmacology sections of regulatory submissions.
ExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Bolt Biotherapeutics, based in the San Francisco Bay Area, is a clinical-stage biotechnology company developing Boltbody™ Immune-stimulating Antibody Conjugates (ISACs), a new class of immuno-oncology therapeutics.
Full-timeExpandApply NowActive JobUpdated 29 days ago - UpvoteDownvoteShare Job
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Support antibody expression construct generation by molecular cloning, DNA sequencing, and plasmid DNA purification. Antibody characterization/QC by SDS-PAGE, HPLC-SEC, and Gator to determine antibody quantity and quality.
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You will be reporting to our Chief Scientific Officer & Head of Research, and you will manage a team of research biologists and project team leaders and work across teams including Antibody and Protein Engineering, Nonclinical sciences, Tech Ops, and CMC.
Full-timeExpandUpdated 4 days ago
antibody job in San Francisco, CA
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