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With both in vitro and in vivo models for kidney biology, biomarker development, and exosomes knowledge. knowledge of microRNA biology, disease-based cell modeling, and in vivo preclinical disease models.
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The successful candidate will work collaboratively with Translational Genetics and Discovery Chemistry to identify new therapeutic areas for application of the TRiM platform technology and develop appropriate in vitro and in vivo models for proof of concept studies and drug discovery activities.
$215,000 - $270,000ExpandApply NowActive JobUpdated 16 days ago - UpvoteDownvoteShare Job
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The candidate will execute in vivo, small animal medical imaging studies and related in vivo pharmacology procedures, including nuclear medicine (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI.
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Capstan Therapeutics, Inc. is a privately held biotechnology company dedicated to advancing in vivo cell reprogramming. tLNPs are designed to deliver payloads, including mRNA or gene editing tools, capable of reprogramming specific cell types in vivo.
$65,000 - $90,000 a yearExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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As a Postdoctoral Scientist, plan and conduct experiments in vitro to manipulate induced pluripotent stem cells, (iPSC) combined with biomaterials in bioreactors and organ-on-chip systems and will manage in vivo regeneration applications with PI’s and lab staff’s support.
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The candidate will develop and lead implementation of strategies and assays to profile siRNA using biochemical and in vivo assays across a range of therapeutic areas. Lead design and execution of biochemical and in vivo assays to drive real time decision making with rapid and high-quality data in support of our objectives.
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Calibr-Skaggs supplements the discovery process with the required disciplines for drug development which include chemical library screening, medicinal chemistry, in-vivo model optimization, formulation development, pharmacokinetic and toxicologic expertise, and early clinical development.
ExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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In collaboration with AbbVie About the Role: Plays a key leadership role in developing our in vitro and in vivo strategies towards target identification and drug discovery, through to clinical candidate selection.
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Responsible for the development and execution of in vitro or ex vivo assays to characterize receptor binding, signaling, cell activation/suppression, and other functional readouts using a variety of techniques including flow cytometry-based assays, ELISA, and reporter assays.
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The Research Associate will be responsible for performing in vivo studies including compound dosing, sample collection and analysis for data generation. Perform in vivo lab procedures including but not limited to rodent dosing (ip, iv, sc, im, etc.
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Design and partner on bench, Pre-Clinical, and Clinical studies as needed for feasibility assessments and build correlations of in vivo to in vitro methodologies. Candidates must have prior project leadership experience, in vivo experience, and early front end research experience.
$170,000 - $185,000 a yearFull-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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Develop assays and methods for in vitro and in vivo enzymatic manipulation of DNA for circularizing short DNA fragments. Develop assays and methods for in vitro and in vivo enzymatic manipulation of DNA for circularizing short DNA fragments.
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These include intellectual input and decision-making on protein targets to be pursued, development of immunogens and immunization strategies, utilization of hybridoma technology, and antibody validation in vitro and in vivo.
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Known for their high quality and expansive in vivo, in vitro, and ex vivo preclinical models, they partner with their clients to quantify the efficacy and pharmacological profile of their drug candidate before they move into the clinic.
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Proven track record of leading successful in vivo pharmacology studies in rodents, including disease modeling. Design and implement in vivo studies using rodent models to evaluate the pharmacokinetics, pharmacodynamics, and therapeutic efficacy of antibody candidates.
Full-timeExpandApply NowActive JobUpdated 14 days ago
vivo job in San Diego, CA
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