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We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development.
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Assume the functional role of Principal Investigator or Study Director for preclinical ophthalmic studies. Manage the conduct of preclinical studies, evaluated the data, and assist in the writing and review of final reports.
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Contribute as local SME to the design, execution and interpretation of preclinical safety, biocompatibility, analytical chemistry, and toxicological evaluation strategies and programs according to relevant regulatory requirements; including review of literature and assessment of compliance.
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This position will function within the Toxicology Unit of Corporate Preclinical Development and Toxicology (CPDT) and will support the conduct of nonclinical laboratory investigations of medical devices and materials in accordance with GLP regulations and the BD CPDT Quality System.
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It has established strategic collaborations with GSK, Amgen, Pfizer and Gilead supporting certain clinical and preclinical pipeline programs. IDEAYA Biosciences (NASDAQ: IDYA) is a public, clinical-stage precision medicine oncology company committed to the discovery and development of targeted therapeutics for patient populations selected using DNA sequencing and other molecular diagnostics.
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This position will function within the Toxicology Unit of Corporate Preclinical Development and Toxicology (CPDT) and will support the conduct of nonclinical laboratory investigations of medical devices and materials in accordance with GLP regulations and the client's CPDT Quality System.
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Experience in a virtual biotech setting working with external CDMO and CRO based resources for preclinical activities, production of drug substance and drug product, testing, and CTM labeling is a plus.
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The successful candidate will also perform preclinical studies in mice and rabbits. The successful candidate will perform a variety of techniques, including cloning and expression of recombinant proteins, tissue culture, protein purification, and preparation for mass spectrometry analysis.
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The Research Assistant II will learn new techniques and apply these toward advancing understanding of cancer biology and assessing preclinical cancer treatment. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children's diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities.
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Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and Cell & Gene Therapy products.
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The Research Associate 1, In Vivo Pharmacology, will be responsible for maintaining inventory, prepping for experiments, and providing experimental support for preclinical in vivo experiments. Assist in the conduct of preclinical in vivo experiments to evaluate the pharmacodynamics, pharmacokinetics, and safety of therapeutic candidate molecules.
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The Open Innovation Associate will be responsible for supporting the evaluation and execution of external opportunities (projects, assets, technologies) as well as strategic partnership management activities at early discovery or preclinical stages to enrich the KKUS Research pipeline in the 4 focus areas of Heme-Oncology, Hematology, Rare Diseases and Bone Mineral Diseases.
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Successful candidate will have a strong understanding of the drug development process from preclinical pharmacology through to regulatory approval and the principles, concepts, practices, and standards of pharmaceutical program management.
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You will work with an outstanding team of molecular biologists, protein engineers, gene-editing experts, pharmacologists, organic chemists, and formulation scientists to create new and effective approaches to deliver our innovative platforms into preclinical mouse models.
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Execute and analyze molecular assays designed to determine gene editing outcomes (nucleic acid extraction, PCR, Sanger-sequencing, NGS library preparation, Amplicon-seq, Flow cytometry). Extensive hands-on experience with Molecular Biology (as PCR, qRT-PCR, ddPCR, DNA/RNA and protein preparation), Cloning, mammalian cell culture and transfection is required.
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preclinical job in San Diego, CA
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