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Advanced knowledge of any or all of the following: complex organic synthesis, parallel synthesis, data analysis, lab automation, and purification in the optimization of lead compounds. Provides expertise in medicinal chemistry principles, complex small molecule synthesis, purification, and data analysis.
$125,700 - $182,250 a yearFull-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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The Production Chemist is responsible for completing tasks and assignments in accordance with established processes and methodologies, synthesize peptides, intermediates and perform processing from initial stage through purification and lyophilization to obtain the final product.
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Performing DNbased labwork independently such as: aqueous chemical reactions on DNA–small molecule conjugates; DNA ligation or other molecular biology techniques; purification of DNA conjugates with High-Performance Liquid Chromatography (HPLC) or other techniques; analysis of DNsmall molecule conjugate compositions through mass spectrometry, electrophoresis, DNA quantitation and other relevant methods.
$104,000 - $166,750 a yearFull-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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Expert in ELISA techniques, flow cytometry, cell culture, immunoassays, antibody purification, and mouse handling, including immunizations, spleen removals, hybridomas, etc. Expert in ELISA techniques, flow cytometry, cell culture, immunoassays, antibody purification, and mouse handling, including immunizations, spleen removals, hybridomas, etc.
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Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein purification and analysis. Design, synthesize and characterize peptides, small proteins and chemically-modified analogs using state-of-the-art synthesis, bioconjugation, purification, analytical and biophysical techniques.
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The potential exists to learn basic lab techniques such as nucleic acid isolation and purification, cloning, PCR, protein purification and cell culture as time, interest and ability permit.
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Basic tissue culture and purification responsibilities include performing cell culture work, antibody purification, conjugation, and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, and specificity measurement by assigned methods.
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You have experience working with and developing assays (keywords include: lateral flow assays (LFA), immunoassays, ELISA, In Vitro Diagnostics (IVD), point-of-care diagnostics, rapid diagnostic tests, paper-based sensors, biosensors, microfluidic, bioconjugation, nanoparticle conjugation, antibody purification.
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Expertise in a range of biochemistry techniques, including protein expression, purification, and characterization. Knowledge of drug discovery processes, including assay development and high-throughput screening.
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Experience in mammalian cell culture, protein expression platforms (i.e. HEK, CHO, or E. coli), and an understanding of protein purification techniques is preferred. Skills in molecular biology including DNA isolation and purification, construct design, and cloning are required.
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Must have direct experience with oligo synthesis equipment (e.g., AKTA Oligopilot, AKTA Pilot/Beckman Purification systems, Dionex/Vanquish HPLC analytical systems, rotary evaporators). The main responsibility for the Synthesis and Production Microbiology Supervisor is to lead and oversee all production activities associated with oligo synthesis and production microbiology in a multi-product cGMP facility.
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Hands-on experience with protein purification (HPLC, FPLC, SEC, IEX, IMAC, etc.) Hands-on experience with protein purification (HPLC, FPLC, SEC, IEX, IMAC, etc.) using the AKTA and Agilent HPLC systemsis required.
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Skill and ability to maintain a variety of written and/or computer records for research activities including Standard Operating Procedures, quality control records, supply inventories, safety records, sequenced DNA library database, nucleic acid isolation and purification logs, etc.
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Growth and maintenance, principally of the specified US Territory through direct sales/after-sales support of purification products and services to our customers within the biopharmaceutical sector.
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The successful candidate will perform a variety of techniques, including cloning and expression of recombinant proteins, tissue culture, protein purification, and preparation for mass spectrometry analysis.
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purification job in La Jolla, CA
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