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Experience with organic chemistry. Knowledge of methods for protein purification, conjugation to fluorochrome and haptens, flow cytometry, immunochemical and immunoassay techniques highly desirable.
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The Director, DMPK will report to the Vice President of DMPK and will primarily liaise with our highly dynamic Chemistry, Pharmacology, and Toxicology departments to develop strategies and advance discovery programs to the clinic.
$173,000 - $230,000 a yearFull-timeExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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Calibr-Skaggs supplements the discovery process with the required disciplines for drug development which include chemical library screening, medicinal chemistry, in-vivo model optimization, formulation development, pharmacokinetic and toxicologic expertise, and early clinical development.
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Prior experience must include: Understand chemistry and biology to analyze data and discuss with other researchers to plan strategies for drug discovery projects; independently design and implement scientific research projects relating to the development of oligonucleotide therapeutics; perform and direct synthesis of organic molecules, including chemically modified oligonucleotides; plan assay designs and manage technicians, including both in-house and external CROs to execute them.
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Experience with protein purification using an AKTA system and protein characterization using HPLC (analytical SEC), SDS-PAGE, and mass spectrometry. Through the application of our proprietary chemoproteomics platform merged with innovative biology and medicinal chemistry, we are modulating protein function in previously unidentified ways to push the limits of drug discovery.
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Fast-paced and collaborative environment as an Associate Scientist within the Analytical and Formulation group of Avidity’s Chemistry, Manufacturing and Controls (CMC) department. Experience in oligonucleotide chemistry and characterization methods.
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Responsibilities include general lab support such as basic biochemical analyses; protein purification, plasmid construction, tissue culture, gel preparation and Western blot analysis. We work hand-in-hand with researchers of the Scripps Research Translational Institute and Calibr to merge foundational studies in biology, chemistry and computer science with translational science to produce pioneering drugs and advances in digital and precision medicine.
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Bachelors Degree in an Occupational Safety and Health discipline (e.g., OS&H Management, Industrial Hygiene, Ergonomics, Human Factors, or another applicable technical field chemistry, biology, engineering, physiology) or equivalent and relevant professional safety experience.
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Collaborate with research, analytical development and process development teams to develop, qualify/validate AAV gene therapy cell-based biological potency assays, protein chemistry assays, and molecular biology assays for process monitoring and drug product release, specifically SDS-PAGE, western blot, droplet digital PCR or qPCR, culture of primary mammalian cells, and cell-based potency assays.
$84,000 - $118,667 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Basic tissue culture and purification responsibilities include performing cell culture work, antibody purification, conjugation, and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, and specificity measurement by assigned methods.
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Catalent Pharma Solutions in San Diego is a premier pharmaceutical chemistry development and manufacturing organization supporting the pharmaceutical and biotechnology industries. Daily responsibilities vary and include production equipment set up, weighing of materials, sieve and blending activities, spray drying, milling, granulation, mixing, roller compaction, submitting samples, encapsulation, tableting, coating and packaging.
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We operate at the intersection of biochemistry, chemistry, hardware, molecular biology, photonics, semiconductor chips, and software with a goal to drive a digital transformation of a $44 billion dollar proteomics market.
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Growth and maintenance, principally of the specified US Territory through direct sales/after-sales support of purification products and services to our customers within the biopharmaceutical sector.
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Must have direct experience with oligo synthesis equipment (e.g., AKTA Oligopilot, AKTA Pilot/Beckman Purification systems, Dionex/Vanquish HPLC analytical systems, rotary evaporators). Must have prior experience in managing or establishing a chemistry/biology laboratory with all applicable safety control systems.
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Maravai LifeSciences is seeking a #MiracleMaker to join our Research & Development teamas a Research Intern, Chemistry R&D. In this role you will gain hands on experience with on mRNA synthesis.
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purification organic chemistry jobs Company: Genomatica in Coronado, CA
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