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Excellent proficiency in molecular biological techniques including DNA purification, molecular cloning, protein purification. Calibr-Skaggs supplements the discovery process with the required disciplines for drug development which include chemical library screening, medicinal chemistry, in-vivo model optimization, formulation development, pharmacokinetic and toxicologic expertise, and early clinical development.
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Thorough understanding of enzyme kinetics and stability. Experience leading root-cause identification of enzyme performance and implement mitigations. Develop assays and methods for in vitro and in vivo enzymatic manipulation of DNA for circularizing short DNA fragments.
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Performing DNbased labwork independently such as: aqueous chemical reactions on DNA–small molecule conjugates; DNA ligation or other molecular biology techniques; purification of DNA conjugates with High-Performance Liquid Chromatography (HPLC) or other techniques; analysis of DNsmall molecule conjugate compositions through mass spectrometry, electrophoresis, DNA quantitation and other relevant methods.
$104,000 - $166,750 a yearFull-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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Our technical foundation lies in advanced protein expression and enzyme engineering, and we deploy these technologies in commercially proven platforms. Protein expression and purification.
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The Fleet Solutions group provides turnkey overhaul / repair, testing, and parts sales for air compressors, main propulsion steam turbines, valves, steam turbine generators, auxiliary turbines, dehydrators, pumps, strainers, PLCs, blowers, and water purification.
$49,000 - $71,700 a yearFull-timeExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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The Research Associate will be responsible for conducting hands-on experiments including but not limited to molecular biology, mammalian cell culture, recombinant protein purification and characterization.
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Experience with T-cell characterization methods (flow cytometry (multiparametric and ICS), cell-based assays (proliferation, cytotoxicity), ELISA, multiplex cytokine assays,purification using MACS system, etc.
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Experience with diverse purification approaches for different antibody formats, analytical characterization (SEC-HPLC, cGE, mass spec, cIEF, SEC-MALS), and developability assessment (thermal stability, poly specificity, hydrophobicity, forced degradation, serum stability) is required.
Full-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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Must have direct experience with oligo synthesis equipment (e.g., AKTA Oligopilot, AKTA Pilot/Beckman Purification systems, Dionex/Vanquish HPLC analytical systems, rotary evaporators). The main responsibility for the Synthesis and Production Microbiology Supervisor is to lead and oversee all production activities associated with oligo synthesis and production microbiology in a multi-product cGMP facility.
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Especially relevant experience may include but not be limited to biomass dewatering and pretreatment, solvent extraction, oil purification, and petrochemical processes. The Chemical Engineer will be responsible for process development programs aimed at harvesting, extraction, and processing algal biomass to produce a drop-in renewable fuel feedstock, enabling our core algal engineering efforts to advance toward biofuel commercial production.
Full-timeExpandApply NowActive JobUpdated 20 days ago - UpvoteDownvoteShare Job
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Basic tissue culture and purification responsibilities include performing cell culture work, antibody purification, conjugation, and associated quality control steps including purity analysis, isotype testing, mycoplasma detection, and specificity measurement by assigned methods.
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Experience in mammalian cell culture, protein expression platforms (i.e. HEK, CHO, or E. coli), and an understanding of protein purification techniques is preferred. Skills in molecular biology including DNA isolation and purification, construct design, and cloning are required.
$41,746 - $75,000 a yearFull-timeExpandUpdated 22 days ago - UpvoteDownvoteShare Job
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Significant expertise in protein biochemistry, including recombinant protein expression, purification and characterization is a plus. Successful candidates will be talented, highly motivated, creative individuals, able to work semi-independently, and have a strong background in either computational protein design, immunology, or protein biochemistry with an emphasis on immunology.
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The successful candidate will perform a variety of techniques, including cloning and expression of recombinant proteins, tissue culture, protein purification, and preparation for mass spectrometry analysis.
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Research Associate I-II, Discovery Chemistry – Oligonucleotide (Purification) Characterization and purification of novel oligonucleotides using HPLC and LCMS. We are looking for candidates as Research Associate I or II, Oligonucleotide Chemistry to join our discovery chemistry team to advance cutting-edge RNA editing drug discovery programs.
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purification enzyme jobs Company: Genomatica in Coronado, CA
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