{"schemaVersion":"jobsearcher.job.v1","id":"c8a574df9bbbdcbdd1795531","url":"https://jobsearcher.com/jobs/c8a574df9bbbdcbdd1795531","canonicalUrl":"https://jobsearcher.com/jobs/c8a574df9bbbdcbdd1795531","title":"Director, Statistical Programming","description":"Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.\r\nOur lead product candidate, lysergidetartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.\r\nGuided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.\r\nTogether we are moving psychiatry forward—beyond better, into a boundless future. Join us!\r\nAs Director, Statistical Programming, this person will provide statistical programming leadership to support analysis and reporting for assigned clinical programs, as well as to support pipeline compounds’ regulatory filing and commercialization. Reporting to Vice President, Head of Biometrics and Data Science, this person will lead a group of Statistical Programmers to deliver while also being hands‑on. This individual will work closely with biostatisticians for data analysis, vendor supervision and provide programming leadership to support Definium’s integrated data analyses and integrated data packages for regulatory filing. This role will be an integral part of multi-functional project team to provide strategic and technical input as one of the subject‑matter-experts.\r\nResponsibilitiesManage a group of statistical programmers to provide programming support for assigned projects from datasets creation (or validation) to data analysis\r\nJoin the regulatory filing team and serve as the lead statistical programmer to support integrated data analyses and ensure all data requirements are met for regulatory filing\r\nResponsible for delivering high quality analysis datasets (SDTM and ADaM) from meeting CDISC standards to ensuring accuracy of all derived variables either for assigned clinical trials or for integrated databases\r\nResponsible for delivering high quality integrated databases to support integrated safety and efficacy analyses\r\nResponsible for high quality DEFINE packages for SDTM and ADaM either for assigned clinical trials or for integrated databases\r\nWork closely with biostatisticians to manage vendor’s deliverables from quality to timeline\r\nPerform statistical data analysis using own SAS programs as needed to support decision making, regulatory communication or drug product commercialization\r\nPerform independent validation using own SAS programs to ensure accuracy of statistical vendor’s deliverables\r\nParticipate in developing necessary SOPs or processes governing statistical programing activities\r\nQualifications and SkillsMaster's Degree in Biostatistics, Statistics, Computer Science or other relevant fields with at least 15 years of experience in using statistical programming to support clinical trial data analysis in pharmaceutical, biotech or CRO environment\r\nRich experience of building and leading statistical programming groups to deliver across programs often with competing priorities\r\nDeep understanding about data standards with solid knowledge in creating DEFINE packages to support regulatory filing\r\nProficient in statistical computational software such as SAS, including complicated data steps, SAS macro languages, and commonly used analysis procedures (e.g., PROC Freq, PROC REPORT, PROC GLM, and PROC MIXED)\r\nExtensive experience in managing statistical vendors to deliver with quality and speed and within the budget\r\nStrong organizational skills, project and resources management skills\r\nDetail-oriented and hold high standards of excellence for Statistical Programming group’s deliverables\r\nDeliver and communicate effectively in the work-from-home environment\r\nStrong track record of problem solving with demonstrated interests of continued learning and growing\r\nExcellent interpersonal skills and is a good team player\r\nPreferred ExperienceExperience in providing statistical programming support for CNS clinical trials\r\nExperience in providing statistical programming support for regulatory filing\r\nThe starting base pay range for this position is $216,951.00 - $241,497.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\r\nEmployees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:\r\n100% paid health benefits including Medical, Dental and Vision for you and your dependents\r\n401(k) program with company match and vesting after the turn of the first month after your start date\r\nFlexible time off\r\nGenerous parental leave and some fun fringe perks!#J-18808-Ljbffr","company":"Psychedelic Alpha","rawCompany":"psychedelic alpha","city":"New York","state":"NY","isRemote":false,"isActive":false,"createdAt":"2026-06-19T01:18:49.116Z","occupations":[{"code":"15-2041.01","title":"Biostatisticians","slug":"biostatisticians"},{"code":"15-2041.00","title":"Statisticians","slug":"statisticians"},{"code":"11-9121.00","title":"Natural Sciences Managers","slug":"natural-sciences-managers"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"325412","title":"Pharmaceutical Preparation Manufacturing","slug":"pharmaceutical-preparation-manufacturing"},{"code":"623220","title":"Residential Mental Health and Substance Abuse Facilities","slug":"residential-mental-health-and-substance-abuse-facilities"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Director, Statistical Programming","description":"Definium Therapeutics is a late-stage clinical biopharmaceutical company and our mission is to forge a new era of psychiatry by applying scientific rigor to psychedelics, with the goal of developing accessible treatments that unlock healing at scale.\r\nOur lead product candidate, lysergidetartrate (our proprietary orally disintegrating tablet form of lysergide (LSD) D-tartrate), represents a highly differentiated, potential best-in-class opportunity for patients suffering from generalized anxiety, major depressive disorder, and posttraumatic stress disorder. Our early stage pipeline includes DT402, the R-enantiomer of MDMA and is under development to target the core symptoms of autism spectrum disorder (ASD), specifically addressing social communication challenges.\r\nGuided by the recognition that patients deserve more than better, Definium is relentlessly advancing a new generation of therapeutics intended to address the underlying causes of psychiatric and neurological disorders. By turning evidence into impact, Definium aims to change the trajectory of today’s mental health care crisis and enable a healthier future. Headquartered in New York, Definium Therapeutics trades on Nasdaq under the symbol DFTX.\r\nTogether we are moving psychiatry forward—beyond better, into a boundless future. Join us!\r\nAs Director, Statistical Programming, this person will provide statistical programming leadership to support analysis and reporting for assigned clinical programs, as well as to support pipeline compounds’ regulatory filing and commercialization. Reporting to Vice President, Head of Biometrics and Data Science, this person will lead a group of Statistical Programmers to deliver while also being hands‑on. This individual will work closely with biostatisticians for data analysis, vendor supervision and provide programming leadership to support Definium’s integrated data analyses and integrated data packages for regulatory filing. This role will be an integral part of multi-functional project team to provide strategic and technical input as one of the subject‑matter-experts.\r\nResponsibilitiesManage a group of statistical programmers to provide programming support for assigned projects from datasets creation (or validation) to data analysis\r\nJoin the regulatory filing team and serve as the lead statistical programmer to support integrated data analyses and ensure all data requirements are met for regulatory filing\r\nResponsible for delivering high quality analysis datasets (SDTM and ADaM) from meeting CDISC standards to ensuring accuracy of all derived variables either for assigned clinical trials or for integrated databases\r\nResponsible for delivering high quality integrated databases to support integrated safety and efficacy analyses\r\nResponsible for high quality DEFINE packages for SDTM and ADaM either for assigned clinical trials or for integrated databases\r\nWork closely with biostatisticians to manage vendor’s deliverables from quality to timeline\r\nPerform statistical data analysis using own SAS programs as needed to support decision making, regulatory communication or drug product commercialization\r\nPerform independent validation using own SAS programs to ensure accuracy of statistical vendor’s deliverables\r\nParticipate in developing necessary SOPs or processes governing statistical programing activities\r\nQualifications and SkillsMaster's Degree in Biostatistics, Statistics, Computer Science or other relevant fields with at least 15 years of experience in using statistical programming to support clinical trial data analysis in pharmaceutical, biotech or CRO environment\r\nRich experience of building and leading statistical programming groups to deliver across programs often with competing priorities\r\nDeep understanding about data standards with solid knowledge in creating DEFINE packages to support regulatory filing\r\nProficient in statistical computational software such as SAS, including complicated data steps, SAS macro languages, and commonly used analysis procedures (e.g., PROC Freq, PROC REPORT, PROC GLM, and PROC MIXED)\r\nExtensive experience in managing statistical vendors to deliver with quality and speed and within the budget\r\nStrong organizational skills, project and resources management skills\r\nDetail-oriented and hold high standards of excellence for Statistical Programming group’s deliverables\r\nDeliver and communicate effectively in the work-from-home environment\r\nStrong track record of problem solving with demonstrated interests of continued learning and growing\r\nExcellent interpersonal skills and is a good team player\r\nPreferred ExperienceExperience in providing statistical programming support for CNS clinical trials\r\nExperience in providing statistical programming support for regulatory filing\r\nThe starting base pay range for this position is $216,951.00 - $241,497.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location.\r\nEmployees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including:\r\n100% paid health benefits including Medical, Dental and Vision for you and your dependents\r\n401(k) program with company match and vesting after the turn of the first month after your start date\r\nFlexible time off\r\nGenerous parental leave and some fun fringe perks!#J-18808-Ljbffr","datePosted":"2026-06-19T01:18:49.116Z","dateModified":"2026-06-19T01:18:49.116Z","hiringOrganization":{"@type":"Organization","name":"Psychedelic Alpha","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"New York","addressRegion":"NY","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"c8a574df9bbbdcbdd1795531"},"url":"https://jobsearcher.com/jobs/c8a574df9bbbdcbdd1795531"}}