{"schemaVersion":"jobsearcher.job.v1","id":"bdb348ee8baf76fefe1a29cf","url":"https://jobsearcher.com/jobs/bdb348ee8baf76fefe1a29cf","canonicalUrl":"https://jobsearcher.com/jobs/bdb348ee8baf76fefe1a29cf","title":"Downstream Process Scientist","description":"Job Title: Senior Research Associate I – Downstream Process Development (Protein Purification)\r\nJob Summary\r\nWe are seeking a highly motivatedSenior Research Associate Ito supportprocess development activitiesfocused onbiologics purification . This role involves hands-on laboratory work, execution of purification experiments, data analysis, and collaboration with cross-functional teams to support process optimization, characterization, and technology transfer to GMP manufacturing.\r\nKey Responsibilities\r\nPlan and execute laboratory experiments to supportdownstream process developmentand project goals\r\nPerform protein purification using techniques such aschromatography, tangential flow filtration (UF/DF), and filtration\r\nAnalyze and interpret experimental data, ensuring data quality and identifying anomalies\r\nContribute toprocess optimization, characterization, and scale-up activities\r\nCollaborate with cross-functional teams including Process Development, Analytical, and Manufacturing\r\nSupporttechnology transfer activitiesfrom development to GMP manufacturing\r\nAssist in troubleshooting purification processes and recommending improvements\r\nDocument experimental results and contribute totechnical reports, validation documents, and regulatory filings\r\nPresent data, results, and conclusions in team meetings\r\nMaintain compliance withcGMP and safety standards , including handling potent compounds upon training\r\nRequired Qualifications\r\nBS degreein Chemical Engineering, Biochemical Engineering, Biochemistry, Chemistry, or related field with2+ years of relevant experience , OR\r\nMS degreein a relevant scientific discipline\r\nPreferred Qualifications\r\nHands-on experience inbiologics purification / downstream process development\r\nExperience withtangential flow filtration (TFF/UFDF), chromatography, and filtration techniques\r\nFamiliarity with purification ofmonoclonal antibodies (mAbs)or other biologics (e.g., bispecifics, fusion proteins, ADCs)\r\nExposure toanalytical techniquessuch as SEC-HPLC, CE (reducing/non-reducing), or HCP testing\r\nKnowledge ofcGMP environments, process scale-up, and technology transfer\r\nUnderstanding of downstream unit operations including centrifugation, filtration, chromatography, and virus clearance\r\nSkills & Competencies\r\nStrong experimental design and problem-solving skills\r\nAbility to analyze and interpret complex scientific data\r\nExcellenttechnical writing and documentation skills\r\nEffective communication and collaboration in ateam-oriented environment\r\nSelf-motivated, detail-oriented, and eager to learn\r\nWork Environment\r\nOn-site laboratory role\r\nRequires adherence to safety protocols and handling ofpotent compounds\r\nNice to Have\r\nExperience with multiple expression systems (mammalian and microbial)\r\nExposure to regulatory documentation and process validation","company":"Cube Hub","rawCompany":"cube hub","city":"Oceanside","state":"CA","isRemote":false,"isActive":false,"createdAt":"2026-05-03T03:51:57.004Z","occupations":[{"code":"19-1042.00","title":"Medical Scientists, Except Epidemiologists","slug":"medical-scientists-except-epidemiologists"},{"code":"19-1029.02","title":"Molecular and Cellular Biologists","slug":"molecular-and-cellular-biologists"},{"code":"19-2031.00","title":"Chemists","slug":"chemists"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"325414","title":"Biological Product (except Diagnostic) Manufacturing","slug":"biological-product-except-diagnostic-manufacturing"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Downstream Process Scientist","description":"Job Title: Senior Research Associate I – Downstream Process Development (Protein Purification)\r\nJob Summary\r\nWe are seeking a highly motivatedSenior Research Associate Ito supportprocess development activitiesfocused onbiologics purification . This role involves hands-on laboratory work, execution of purification experiments, data analysis, and collaboration with cross-functional teams to support process optimization, characterization, and technology transfer to GMP manufacturing.\r\nKey Responsibilities\r\nPlan and execute laboratory experiments to supportdownstream process developmentand project goals\r\nPerform protein purification using techniques such aschromatography, tangential flow filtration (UF/DF), and filtration\r\nAnalyze and interpret experimental data, ensuring data quality and identifying anomalies\r\nContribute toprocess optimization, characterization, and scale-up activities\r\nCollaborate with cross-functional teams including Process Development, Analytical, and Manufacturing\r\nSupporttechnology transfer activitiesfrom development to GMP manufacturing\r\nAssist in troubleshooting purification processes and recommending improvements\r\nDocument experimental results and contribute totechnical reports, validation documents, and regulatory filings\r\nPresent data, results, and conclusions in team meetings\r\nMaintain compliance withcGMP and safety standards , including handling potent compounds upon training\r\nRequired Qualifications\r\nBS degreein Chemical Engineering, Biochemical Engineering, Biochemistry, Chemistry, or related field with2+ years of relevant experience , OR\r\nMS degreein a relevant scientific discipline\r\nPreferred Qualifications\r\nHands-on experience inbiologics purification / downstream process development\r\nExperience withtangential flow filtration (TFF/UFDF), chromatography, and filtration techniques\r\nFamiliarity with purification ofmonoclonal antibodies (mAbs)or other biologics (e.g., bispecifics, fusion proteins, ADCs)\r\nExposure toanalytical techniquessuch as SEC-HPLC, CE (reducing/non-reducing), or HCP testing\r\nKnowledge ofcGMP environments, process scale-up, and technology transfer\r\nUnderstanding of downstream unit operations including centrifugation, filtration, chromatography, and virus clearance\r\nSkills & Competencies\r\nStrong experimental design and problem-solving skills\r\nAbility to analyze and interpret complex scientific data\r\nExcellenttechnical writing and documentation skills\r\nEffective communication and collaboration in ateam-oriented environment\r\nSelf-motivated, detail-oriented, and eager to learn\r\nWork Environment\r\nOn-site laboratory role\r\nRequires adherence to safety protocols and handling ofpotent compounds\r\nNice to Have\r\nExperience with multiple expression systems (mammalian and microbial)\r\nExposure to regulatory documentation and process validation","datePosted":"2026-05-03T03:51:57.004Z","dateModified":"2026-05-03T03:51:57.004Z","hiringOrganization":{"@type":"Organization","name":"Cube Hub","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Oceanside","addressRegion":"CA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"bdb348ee8baf76fefe1a29cf"},"url":"https://jobsearcher.com/jobs/bdb348ee8baf76fefe1a29cf"}}