{"schemaVersion":"jobsearcher.job.v1","id":"b80849a863abeefdb8fccc48","url":"https://jobsearcher.com/jobs/b80849a863abeefdb8fccc48","canonicalUrl":"https://jobsearcher.com/jobs/b80849a863abeefdb8fccc48","title":"Lead System Engineer","description":"Title: Lead Design Engineer\nLocation: Onsite, Pittsburgh, PA 15213\nType: Direct-Hire/Permanent\nHours: Standard business hours\nStart: May\nOverview: Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant experimental platforms. This role focuses on ensuring precise, reproducible generation and delivery of airborne agents, as well as integration of instrumentation and multi-system platforms to enable controlled and standardized experimental workflows. The position will contribute to system optimization, performance validation, and operational readiness in complex laboratory environments.\n\nResponsibilities:\nDesign, prototype, and refine biomedical devices and components supporting advanced experimental system\nDevelop and optimize fabrication processes to ensure consistency, quality, and scalability\nContribute to selection and evaluation of materials, fabrication methods, and assembly workflows\nPerform testing and validation of device performance, including durability, reproducibility, and functional integrity\nCollaborate with scientific and engineering teams to align device design with experimental requirements\nMaintain documentation related to design iterations, fabrication processes, and quality control\nTroubleshoot device-related issues and implement design improvements\nSupport coordination of engineering activities across multidisciplinary teams and contribute to project execution\nContribute to preparation of technical documentation, reports, and related materials\nRequirements:\nBachelor’s degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field\nMinimum of 3 years of relevant experience in device design, prototyping, or fabrication\nExperience with engineering design tools (e.g., CAD software)\nStrong problem-solving skills and attention to detail\nAbility to work effectively in multidisciplinary research and engineering environments\nPreferred Qualifications\nMaster’s or Ph.D. in a relevant engineering discipline\nExperience with fabrication of small-scale or precision-engineered devices, including Organs-on-Chips, injection molding, and CNC milling\nFamiliarity with polymer-based materials and manufacturing processes\nExperience with iterative prototyping and design-for-manufacturing principles\nExperience working at the interface of engineering and biological systems\n#M3\n#LI-DS2\nRef: #558-Scientific","company":"Systemone","rawCompany":"systemone","city":"Pittsburgh","state":"PA","isRemote":false,"isActive":false,"createdAt":"2026-07-23T15:56:24.323Z","occupations":[{"code":"17-2031.00","title":"Bioengineers and Biomedical Engineers","slug":"bioengineers-and-biomedical-engineers"},{"code":"17-2199.00","title":"Engineers, All Other","slug":"engineers-all-other"},{"code":"17-2141.00","title":"Mechanical Engineers","slug":"mechanical-engineers"}],"industries":[{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"339113","title":"Surgical Appliance and Supplies Manufacturing","slug":"surgical-appliance-and-supplies-manufacturing"},{"code":"334510","title":"Electromedical and Electrotherapeutic Apparatus Manufacturing","slug":"electromedical-and-electrotherapeutic-apparatus-manufacturing"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Lead System Engineer","description":"Title: Lead Design Engineer\nLocation: Onsite, Pittsburgh, PA 15213\nType: Direct-Hire/Permanent\nHours: Standard business hours\nStart: May\nOverview: Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant experimental platforms. This role focuses on ensuring precise, reproducible generation and delivery of airborne agents, as well as integration of instrumentation and multi-system platforms to enable controlled and standardized experimental workflows. The position will contribute to system optimization, performance validation, and operational readiness in complex laboratory environments.\n\nResponsibilities:\nDesign, prototype, and refine biomedical devices and components supporting advanced experimental system\nDevelop and optimize fabrication processes to ensure consistency, quality, and scalability\nContribute to selection and evaluation of materials, fabrication methods, and assembly workflows\nPerform testing and validation of device performance, including durability, reproducibility, and functional integrity\nCollaborate with scientific and engineering teams to align device design with experimental requirements\nMaintain documentation related to design iterations, fabrication processes, and quality control\nTroubleshoot device-related issues and implement design improvements\nSupport coordination of engineering activities across multidisciplinary teams and contribute to project execution\nContribute to preparation of technical documentation, reports, and related materials\nRequirements:\nBachelor’s degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field\nMinimum of 3 years of relevant experience in device design, prototyping, or fabrication\nExperience with engineering design tools (e.g., CAD software)\nStrong problem-solving skills and attention to detail\nAbility to work effectively in multidisciplinary research and engineering environments\nPreferred Qualifications\nMaster’s or Ph.D. in a relevant engineering discipline\nExperience with fabrication of small-scale or precision-engineered devices, including Organs-on-Chips, injection molding, and CNC milling\nFamiliarity with polymer-based materials and manufacturing processes\nExperience with iterative prototyping and design-for-manufacturing principles\nExperience working at the interface of engineering and biological systems\n#M3\n#LI-DS2\nRef: #558-Scientific","datePosted":"2026-07-23T15:56:24.323Z","dateModified":"2026-07-23T15:56:24.323Z","hiringOrganization":{"@type":"Organization","name":"Systemone","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Pittsburgh","addressRegion":"PA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"b80849a863abeefdb8fccc48"},"url":"https://jobsearcher.com/jobs/b80849a863abeefdb8fccc48"}}