{"schemaVersion":"jobsearcher.job.v1","id":"b1d4a67c7e5fb90afedcf704","url":"https://jobsearcher.com/jobs/b1d4a67c7e5fb90afedcf704","canonicalUrl":"https://jobsearcher.com/jobs/b1d4a67c7e5fb90afedcf704","title":"Associate Scientist - Downstream Process Development","description":"Job Title: Associate Scientist - Downstream Process Development Location: Durham, NC (Onsite) Duration: 18 months Shift: Mon – Friday (8 – 5)About the Role:The Gene Therapy Downstream Process Development Team within Technical Research & Development (TRD) organization drives purification process development for gene therapy assets across both adeno-associated virus (AAV) and lentiviral vector (LVV) modalities.The Associate Scientist - Downstream Process Development (Contract) is a temporary contract position providing hands-on experimental and operational support for defined gene therapy development activities. The role will support the planning, execution, and analysis of assigned experiments in support of gene therapy program initiatives. This role performs hands-on downstream process work at small and large scale and supports the execution of pilot- and large-scale batches. The position is intended to provide focused execution capacity for current program needs, working closely with downstream team members and cross-functional partners.Major Accountabilities:Execute assigned experimental and process activities in support of defined program deliverables, working under the guidance of senior team members.Perform hands-on downstream process operations, such as depth filtration, chromatography, and/or tangential flow filtration (TFF), at both small and large scale.Support the execution of pilot- and large-scale batches, including equipment and materials preparation, process operation, sampling, and documentation.Compile, analyze, and summarize experimental data and share results and observations with the team.Accurately document experimental procedures, observations, and results in accordance with good documentation practices.Prepare and maintain laboratory equipment, buffers, and materials, and help coordinate laboratory activities and supplies for assigned studies.Follow safety requirements, technical standards, and best practices, and contribute ideas for continuous improvement of laboratory processes.Coordinate with downstream team members and cross-functional partners as needed to support timely study and batch execution.Provide flexible, hands-on support across assigned studies and batch activities based on evolving program and team needs.Essential Requirements:Bachelor’s degree in biological sciences, pharmaceutical sciences, chemical engineering, or a related technical field with 2 years of relevant experience; or Master’s degree with 0–1 years of relevant experience.Hands-on experience with at least one of the following downstream unit operations at small or large scale: depth filtration, chromatography, or tangential flow filtration (TFF).Ability to carry out assigned experiments and process operations accurately, following established procedures and protocols.Working knowledge of data analysis and the ability to summarize and communicate experimental results.Strong attention to detail, organizational skills, and commitment to good documentation practices.Effective written and verbal communication skills and the ability to work collaboratively in a team setting. Desired Requirements:Experience supporting pilot- or large-scale batch execution.Knowledge of viral gene therapy and experience with AAV or LVV downstream processes.","company":"Aequor","rawCompany":"aequor","city":"Durham","state":"NC","isRemote":false,"isActive":false,"createdAt":"2026-11-10T08:37:02.040Z","occupations":[{"code":"19-4021.00","title":"Biological Technicians","slug":"biological-technicians"},{"code":"19-4031.00","title":"Chemical Technicians","slug":"chemical-technicians"},{"code":"19-1029.02","title":"Molecular and Cellular Biologists","slug":"molecular-and-cellular-biologists"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"325414","title":"Biological Product (except Diagnostic) Manufacturing","slug":"biological-product-except-diagnostic-manufacturing"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Associate Scientist - Downstream Process Development","description":"Job Title: Associate Scientist - Downstream Process Development Location: Durham, NC (Onsite) Duration: 18 months Shift: Mon – Friday (8 – 5)About the Role:The Gene Therapy Downstream Process Development Team within Technical Research & Development (TRD) organization drives purification process development for gene therapy assets across both adeno-associated virus (AAV) and lentiviral vector (LVV) modalities.The Associate Scientist - Downstream Process Development (Contract) is a temporary contract position providing hands-on experimental and operational support for defined gene therapy development activities. The role will support the planning, execution, and analysis of assigned experiments in support of gene therapy program initiatives. This role performs hands-on downstream process work at small and large scale and supports the execution of pilot- and large-scale batches. The position is intended to provide focused execution capacity for current program needs, working closely with downstream team members and cross-functional partners.Major Accountabilities:Execute assigned experimental and process activities in support of defined program deliverables, working under the guidance of senior team members.Perform hands-on downstream process operations, such as depth filtration, chromatography, and/or tangential flow filtration (TFF), at both small and large scale.Support the execution of pilot- and large-scale batches, including equipment and materials preparation, process operation, sampling, and documentation.Compile, analyze, and summarize experimental data and share results and observations with the team.Accurately document experimental procedures, observations, and results in accordance with good documentation practices.Prepare and maintain laboratory equipment, buffers, and materials, and help coordinate laboratory activities and supplies for assigned studies.Follow safety requirements, technical standards, and best practices, and contribute ideas for continuous improvement of laboratory processes.Coordinate with downstream team members and cross-functional partners as needed to support timely study and batch execution.Provide flexible, hands-on support across assigned studies and batch activities based on evolving program and team needs.Essential Requirements:Bachelor’s degree in biological sciences, pharmaceutical sciences, chemical engineering, or a related technical field with 2 years of relevant experience; or Master’s degree with 0–1 years of relevant experience.Hands-on experience with at least one of the following downstream unit operations at small or large scale: depth filtration, chromatography, or tangential flow filtration (TFF).Ability to carry out assigned experiments and process operations accurately, following established procedures and protocols.Working knowledge of data analysis and the ability to summarize and communicate experimental results.Strong attention to detail, organizational skills, and commitment to good documentation practices.Effective written and verbal communication skills and the ability to work collaboratively in a team setting. Desired Requirements:Experience supporting pilot- or large-scale batch execution.Knowledge of viral gene therapy and experience with AAV or LVV downstream processes.","datePosted":"2026-11-10T08:37:02.040Z","dateModified":"2026-11-10T08:37:02.040Z","hiringOrganization":{"@type":"Organization","name":"Aequor","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Durham","addressRegion":"NC","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"b1d4a67c7e5fb90afedcf704"},"url":"https://jobsearcher.com/jobs/b1d4a67c7e5fb90afedcf704"}}