{"schemaVersion":"jobsearcher.job.v1","id":"ab972dc1b021907f0a59ead9","url":"https://jobsearcher.com/jobs/ab972dc1b021907f0a59ead9","canonicalUrl":"https://jobsearcher.com/jobs/ab972dc1b021907f0a59ead9","title":"Principal Engineer, Algorithm - ECG","description":"Job Summary\r\nThe Principal Engineer, Algorithm - ECG is a senior technical leader responsible for the architecture, development, and advancement of electrocardiogram (ECG) signal processing algorithms that enable accurate, reliable cardiac monitoring in Masimo's non-invasive platforms.\r\nThis role drives innovation in ECG-based measurement, including heart rate, rhythm analysis, and advanced cardiac insights, translating complex physiological signals into clinically actionable outputs. The Principal Engineer partners closely with cross-functional teams across hardware, software, systems, and clinical domains to deliver high-performance, regulatory-compliant solutions from concept through commercialization.\r\nDuties & Responsibilities:\r\n\r\nLead the design and development of advanced ECG signal processing algorithms, including filtering, feature extraction, waveform delineation, and rhythm classification\r\nArchitect scalable algorithm frameworks for ECG analysis, supporting real-time embedded implementation and cloud-based analytics where applicable\r\nDevelop and optimize algorithms for heart rate detection, arrhythmia identification, and ECG morphology analysis\r\nDesign and conduct validation strategies using clinical datasets to ensure algorithm accuracy, robustness, and generalizability across diverse patient populations\r\nAddress signal quality challenges, including motion artifact, noise reduction, and low-perfusion or ambulatory conditions\r\nPartner with hardware and systems teams to ensure optimal signal acquisition and end-to-end system performance\r\nCollaborate with software and firmware teams to implement algorithms on embedded platforms with real-time constraints\r\nTranslate clinical and regulatory requirements into algorithm design inputs, ensuring compliance with applicable standards (e.g., FDA, IEC)\r\nEstablish best practices for algorithm verification, validation, and documentation in regulated environments\r\nProvide technical leadership and mentorship to engineers, contributing to team capability building\r\nDrive innovation and contribute to intellectual property, including patents and technical publications\r\n\r\nMinimum Qualifications\r\n\r\n12+ years of relevant experience in ECG algorithm development, signal processing, or related domain\r\nDeep expertise in ECG signal processing, digital signal processing, and statistical modeling\r\nProven experience developing ECG algorithms, including waveform detection and cardiac feature extraction\r\nStrong programming skills in C/C++, MATLAB, Python, or similar\r\nExperience working with large-scale physiological or clinical datasets\r\nDemonstrated ability to translate complex signal processing challenges into robust, real-time solutions\r\nStrong problem-solving, analytical, and cross-functional collaboration skills\r\nAbility to work onsite Monday - Friday in Irvine, CA\r\n\r\nPreferred Qualifications\r\n\r\n\r\nExperience with arrhythmia detection/classification algorithms or cardiac monitoring systems\r\n\r\n\r\nKnowledge of cardiac physiology and electrophysiology principles\r\n\r\n\r\nExperience applying machine learning techniques to ECG or time-series physiological data\r\n\r\n\r\nFamiliarity with wearable or ambulatory ECG systems and associated signal challenges\r\n\r\n\r\nExperience supporting regulatory submissions (e.g., FDA 510(k), CE Mark)\r\n\r\n\r\nPrior contributions to patents, publications, or clinically validated products\r\n\r\n\r\nEducation\r\nBachelor's degree in Electrical Engineering, Biomedical Engineering, Computer Engineering, or a related field required; Master's or Ph.D. preferred\r\nLanguage requirements\r\n\r\nAbility to read, write, and communicate effectively in English\r\nAbility to interpret technical documents, schematics, and written instructions\r\nAbility to clearly document technical findings and communicate with cross-functional team members\r\n\r\nCompensation\r\nThe anticipated salary range for this position is $170,000 - $215k plus benefits. Actual placement within this range is dependent on multiple factors, including but not limited to skills, education, and experience. This position also qualifies for up to 15% annual bonus based on company, department, and individual performance.\r\nPhysical requirements/Work environment:\r\nThis position primarily works in an office environment and requires frequent sitting, standing, and walking. Daily use of a computer and other digital devices is required. This role may require standing for extended periods when facilitating meetings or walking through facilities. The physical demands of the position described herein are essential functions of the job and employees must be able to successfully perform these tasks for extended periods. Reasonable accommodations may be made for those individuals with real or perceived disabilities to perform the essential functions of the job described.","company":"Masimo","rawCompany":"masimo","city":"Irvine","state":"CA","isRemote":false,"isActive":true,"createdAt":"2026-05-17T04:36:35.066Z","occupations":[{"code":"29-1212.00","title":"Cardiologists","slug":"cardiologists"},{"code":"17-2072.00","title":"Electronics Engineers, Except Computer","slug":"electronics-engineers-except-computer"},{"code":"29-2031.00","title":"Cardiovascular Technologists and Technicians","slug":"cardiovascular-technologists-and-technicians"}],"industries":[{"code":"334510","title":"Electromedical and Electrotherapeutic Apparatus Manufacturing","slug":"electromedical-and-electrotherapeutic-apparatus-manufacturing"},{"code":"541330","title":"Engineering Services","slug":"engineering-services"},{"code":"622310","title":"Specialty (except Psychiatric and Substance Abuse) Hospitals","slug":"specialty-except-psychiatric-and-substance-abuse-hospitals"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Principal Engineer, Algorithm - ECG","description":"Job Summary\r\nThe Principal Engineer, Algorithm - ECG is a senior technical leader responsible for the architecture, development, and advancement of electrocardiogram (ECG) signal processing algorithms that enable accurate, reliable cardiac monitoring in Masimo's non-invasive platforms.\r\nThis role drives innovation in ECG-based measurement, including heart rate, rhythm analysis, and advanced cardiac insights, translating complex physiological signals into clinically actionable outputs. The Principal Engineer partners closely with cross-functional teams across hardware, software, systems, and clinical domains to deliver high-performance, regulatory-compliant solutions from concept through commercialization.\r\nDuties & Responsibilities:\r\n\r\nLead the design and development of advanced ECG signal processing algorithms, including filtering, feature extraction, waveform delineation, and rhythm classification\r\nArchitect scalable algorithm frameworks for ECG analysis, supporting real-time embedded implementation and cloud-based analytics where applicable\r\nDevelop and optimize algorithms for heart rate detection, arrhythmia identification, and ECG morphology analysis\r\nDesign and conduct validation strategies using clinical datasets to ensure algorithm accuracy, robustness, and generalizability across diverse patient populations\r\nAddress signal quality challenges, including motion artifact, noise reduction, and low-perfusion or ambulatory conditions\r\nPartner with hardware and systems teams to ensure optimal signal acquisition and end-to-end system performance\r\nCollaborate with software and firmware teams to implement algorithms on embedded platforms with real-time constraints\r\nTranslate clinical and regulatory requirements into algorithm design inputs, ensuring compliance with applicable standards (e.g., FDA, IEC)\r\nEstablish best practices for algorithm verification, validation, and documentation in regulated environments\r\nProvide technical leadership and mentorship to engineers, contributing to team capability building\r\nDrive innovation and contribute to intellectual property, including patents and technical publications\r\n\r\nMinimum Qualifications\r\n\r\n12+ years of relevant experience in ECG algorithm development, signal processing, or related domain\r\nDeep expertise in ECG signal processing, digital signal processing, and statistical modeling\r\nProven experience developing ECG algorithms, including waveform detection and cardiac feature extraction\r\nStrong programming skills in C/C++, MATLAB, Python, or similar\r\nExperience working with large-scale physiological or clinical datasets\r\nDemonstrated ability to translate complex signal processing challenges into robust, real-time solutions\r\nStrong problem-solving, analytical, and cross-functional collaboration skills\r\nAbility to work onsite Monday - Friday in Irvine, CA\r\n\r\nPreferred Qualifications\r\n\r\n\r\nExperience with arrhythmia detection/classification algorithms or cardiac monitoring systems\r\n\r\n\r\nKnowledge of cardiac physiology and electrophysiology principles\r\n\r\n\r\nExperience applying machine learning techniques to ECG or time-series physiological data\r\n\r\n\r\nFamiliarity with wearable or ambulatory ECG systems and associated signal challenges\r\n\r\n\r\nExperience supporting regulatory submissions (e.g., FDA 510(k), CE Mark)\r\n\r\n\r\nPrior contributions to patents, publications, or clinically validated products\r\n\r\n\r\nEducation\r\nBachelor's degree in Electrical Engineering, Biomedical Engineering, Computer Engineering, or a related field required; Master's or Ph.D. preferred\r\nLanguage requirements\r\n\r\nAbility to read, write, and communicate effectively in English\r\nAbility to interpret technical documents, schematics, and written instructions\r\nAbility to clearly document technical findings and communicate with cross-functional team members\r\n\r\nCompensation\r\nThe anticipated salary range for this position is $170,000 - $215k plus benefits. Actual placement within this range is dependent on multiple factors, including but not limited to skills, education, and experience. This position also qualifies for up to 15% annual bonus based on company, department, and individual performance.\r\nPhysical requirements/Work environment:\r\nThis position primarily works in an office environment and requires frequent sitting, standing, and walking. Daily use of a computer and other digital devices is required. This role may require standing for extended periods when facilitating meetings or walking through facilities. The physical demands of the position described herein are essential functions of the job and employees must be able to successfully perform these tasks for extended periods. Reasonable accommodations may be made for those individuals with real or perceived disabilities to perform the essential functions of the job described.","datePosted":"2026-05-17T04:36:35.066Z","dateModified":"2026-05-17T04:36:35.066Z","hiringOrganization":{"@type":"Organization","name":"Masimo","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Irvine","addressRegion":"CA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"ab972dc1b021907f0a59ead9"},"url":"https://jobsearcher.com/jobs/ab972dc1b021907f0a59ead9"}}