{"schemaVersion":"jobsearcher.job.v1","id":"97e85aebfcaffdebaeaa360a","url":"https://jobsearcher.com/jobs/97e85aebfcaffdebaeaa360a","canonicalUrl":"https://jobsearcher.com/jobs/97e85aebfcaffdebaeaa360a","title":"GxP Systems Engineer","description":"The RoleWe are seeking a GxP Systems Engineer with deep experience in laboratory automation platforms to support validated systems within GMP Quality Control environments. This role will focus on ensuring automated instrumentation and associated digital systems are implemented, integrated, and maintained in a compliant, validated state.You will work at the intersection of automation, validation, and digital integration, with a strong emphasis on liquid handling platforms (e.g., Hamilton) and their role in modern lab workflows.Who You AreYou bring hands-on experience with automated laboratory systems and understand the complexities of validating both instruments and their controlling software. You’re comfortable navigating GMP environments and translating validation requirements into practical execution.You enjoy working close to the technology - troubleshooting, configuring, and improving systems - while ensuring compliance is never compromised.What You’ll DoLead and execute validation activities (IQ/OQ/PQ) for laboratory automation systems, with a focus on liquid handling platforms such as Hamilton VENUS or comparable technologies.Support the implementation, configuration, and lifecycle management of automated instruments and their associated software.Ensure automation workflows, methods, and integrations are developed and maintained in alignment with GxP and data integrity requirements.Collaborate with stakeholders to define system requirements and translate them into validated, scalable automation solutions.Oversee change control activities related to instrument methods, software updates, and system integrations, ensuring validation impact is assessed and documented.Develop and maintain validation deliverables including risk assessments, validation plans, traceability matrices, and periodic review documentation.Support integration of automation platforms with laboratory systems and digital infrastructure, ensuring compliant data transfer and system interoperability.Troubleshoot and support complex automation workflows, ensuring minimal disruption while maintaining validated state.Participate in audits and inspections as a subject matter expert for automation systems and validation practices.Identify opportunities to enhance automation capabilities while maintaining compliance and improving efficiency.Minimum QualificationsBachelor’s degree (or equivalent experience) in engineering, computer science, or a scientific field5+ years of experience supporting automated laboratory systems in a GMP-regulated environmentHands-on experience with Hamilton VENUS or similar liquid handling automation platforms (highly preferred)Strong background in computer system validation (CSV) and instrument validationFamiliarity with GxP, GAMP 5, and data integrity principles (ALCOA+)Experience with laboratory instrumentation integration and automated workflowsUnderstanding of system architecture, including connections between instruments, local systems, and cloud-based platformsPreferred QualificationsExperience designing or optimizing automated liquid handling methods and workflowsFamiliarity with scripting, method development, or configuration within automation platformsExposure to hybrid environments (on-prem + cloud systems)Working knowledge of Linux or similar operating systemsExperience supporting audits and regulatory inspectionsWhat You BringStrong hands-on expertise with lab automation systems, especially liquid handlersA validation-first mindset with the ability to balance compliance and usabilityTechnical curiosity and willingness to troubleshoot and improve complex systemsAbility to work cross-functionally with quality, IT, and laboratory teamsA practical approach to scaling automation in a regulated environment","company":"Arrayo","rawCompany":"arrayo","city":"Newton Center","state":"MA","isRemote":false,"isActive":false,"createdAt":"2026-04-12T18:37:59.597Z","occupations":[{"code":"17-2112.02","title":"Validation Engineers","slug":"validation-engineers"},{"code":"11-3051.01","title":"Quality Control Systems Managers","slug":"quality-control-systems-managers"},{"code":"15-1299.08","title":"Computer Systems Engineers/Architects","slug":"computer-systems-engineers-architects"}],"industries":[{"code":"541512","title":"Computer Systems Design Services","slug":"computer-systems-design-services"},{"code":"334513","title":"Instruments and Related Products Manufacturing for Measuring, Displaying, and Controlling Industrial Process Variables","slug":"instruments-and-related-products-manufacturing-for-measuring-displaying-and-controlling-industrial-process-variables"},{"code":"334516","title":"Analytical Laboratory Instrument Manufacturing","slug":"analytical-laboratory-instrument-manufacturing"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"GxP Systems Engineer","description":"The RoleWe are seeking a GxP Systems Engineer with deep experience in laboratory automation platforms to support validated systems within GMP Quality Control environments. This role will focus on ensuring automated instrumentation and associated digital systems are implemented, integrated, and maintained in a compliant, validated state.You will work at the intersection of automation, validation, and digital integration, with a strong emphasis on liquid handling platforms (e.g., Hamilton) and their role in modern lab workflows.Who You AreYou bring hands-on experience with automated laboratory systems and understand the complexities of validating both instruments and their controlling software. You’re comfortable navigating GMP environments and translating validation requirements into practical execution.You enjoy working close to the technology - troubleshooting, configuring, and improving systems - while ensuring compliance is never compromised.What You’ll DoLead and execute validation activities (IQ/OQ/PQ) for laboratory automation systems, with a focus on liquid handling platforms such as Hamilton VENUS or comparable technologies.Support the implementation, configuration, and lifecycle management of automated instruments and their associated software.Ensure automation workflows, methods, and integrations are developed and maintained in alignment with GxP and data integrity requirements.Collaborate with stakeholders to define system requirements and translate them into validated, scalable automation solutions.Oversee change control activities related to instrument methods, software updates, and system integrations, ensuring validation impact is assessed and documented.Develop and maintain validation deliverables including risk assessments, validation plans, traceability matrices, and periodic review documentation.Support integration of automation platforms with laboratory systems and digital infrastructure, ensuring compliant data transfer and system interoperability.Troubleshoot and support complex automation workflows, ensuring minimal disruption while maintaining validated state.Participate in audits and inspections as a subject matter expert for automation systems and validation practices.Identify opportunities to enhance automation capabilities while maintaining compliance and improving efficiency.Minimum QualificationsBachelor’s degree (or equivalent experience) in engineering, computer science, or a scientific field5+ years of experience supporting automated laboratory systems in a GMP-regulated environmentHands-on experience with Hamilton VENUS or similar liquid handling automation platforms (highly preferred)Strong background in computer system validation (CSV) and instrument validationFamiliarity with GxP, GAMP 5, and data integrity principles (ALCOA+)Experience with laboratory instrumentation integration and automated workflowsUnderstanding of system architecture, including connections between instruments, local systems, and cloud-based platformsPreferred QualificationsExperience designing or optimizing automated liquid handling methods and workflowsFamiliarity with scripting, method development, or configuration within automation platformsExposure to hybrid environments (on-prem + cloud systems)Working knowledge of Linux or similar operating systemsExperience supporting audits and regulatory inspectionsWhat You BringStrong hands-on expertise with lab automation systems, especially liquid handlersA validation-first mindset with the ability to balance compliance and usabilityTechnical curiosity and willingness to troubleshoot and improve complex systemsAbility to work cross-functionally with quality, IT, and laboratory teamsA practical approach to scaling automation in a regulated environment","datePosted":"2026-04-12T18:37:59.597Z","dateModified":"2026-04-12T18:37:59.597Z","hiringOrganization":{"@type":"Organization","name":"Arrayo","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Newton Center","addressRegion":"MA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"97e85aebfcaffdebaeaa360a"},"url":"https://jobsearcher.com/jobs/97e85aebfcaffdebaeaa360a"}}