{"schemaVersion":"jobsearcher.job.v1","id":"8a44e431e4f219d971b0753b","url":"https://jobsearcher.com/jobs/8a44e431e4f219d971b0753b","canonicalUrl":"https://jobsearcher.com/jobs/8a44e431e4f219d971b0753b","title":"Engineer, Process Sciences - Upstream","description":"Encoded Therapeutics is a clinical-stage genetic medicines company developing potentially disease-modifying therapies to improve the lives of people with severe CNS disorders. Our proprietary vector engineering approach combines novel regulatory elements and payloads with AAV vectors to unlock innovative solutions for debilitating, intractable CNS conditions. At the forefront is our flagship clinical program, ETX101 for Dravet syndrome, which targets the underlying cause of the disorder to enable highly selective upregulation ofSCN1Afor potentially long-lasting benefit. In parallel, we are advancing a pipeline of potentially best-in-class programs to address significant unmet needs across both monogenic and prevalent CNS conditions. For more information, please visit www.encoded.com.\nWe are recruiting an Engineer, Process Sciences to join our team. This is a unique opportunity to work at the intersection of genomics and therapeutics and participate in the development of a diverse therapeutic pipeline driven by a transformative core technology. The successful candidate will work well across multiple projects in a fast-paced and dynamic environment.\nResponsibilities Design, execute, and analyze small-scale studies supporting the development of two at-scale products and Encoded’s pipeline products\nServe as an engineer responsible for pre-clinical and clinical manufacturing for AAV projects and plasmid manufacturing; including upstream, downstream, fill finish, and drug device\nFacilitate Encoded’s technology transfer of manufacturing processes to non-GMP/GMP internal and external sites of manufacturing\nProvide person-in-plant support of GMP (clinical and commercial) manufacturing as required at internal and external sites of manufacturing\nWork with cross-functional teams to develop tools/templates to support tech transfer business processes\nRequirements B.S or M.S. in a relevant area of specialization (biochemical engineering, chemical engineering, biological sciences, virology, molecular biology, or biochemistry)\nAt least 3 years of industry experience or equivalent educational experience\nAt least 1 year of industry experience in MSAT/PD/Process Sciences role preferred\nExtensive working knowledge of modern laboratory procedures and knowledge of cGMP is a must\nAbility to independently design, execute, and analyze small-scale cell culture studies (cell expansion, single-use bioreactors, and harvest/clarification) is a must\nMust be a team player and exhibit a willingness to meet project timelines\nStrong verbal and written skills are required as well as effective interpersonal, technical, and troubleshooting skills\nOutstanding planning, organization, and multitasking skills\nExperience with gene therapy processes is strongly preferred\nBenefits Comprehensive benefits package, including competitive employer premium contributions\nMeaningful stock option grants\nPTO, sick time, and holiday pay\nGenerous Parental Leave program\nPre-tax medical and dependent care programs\nSTD, LTD, Life and AD&D\nProfessional development opportunities\nTeam-building events\nStocked micro-kitchen with drinks and snacks\nWellness Resources\nEncoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind.\nEncoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment.\nAll employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate.\nEncoded will not tolerate discrimination or harassment based on any of these characteristics.\nEncoded encourages applicants of all ages.\n\n#J-18808-Ljbffr","company":"Encoded","rawCompany":"encoded","city":"Morrisville","state":"NC","isRemote":false,"isActive":true,"createdAt":"2026-10-04T03:34:00.777Z","occupations":[{"code":"17-2199.00","title":"Engineers, All Other","slug":"engineers-all-other"},{"code":"17-2041.00","title":"Chemical Engineers","slug":"chemical-engineers"},{"code":"17-2031.00","title":"Bioengineers and Biomedical Engineers","slug":"bioengineers-and-biomedical-engineers"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"325414","title":"Biological Product (except Diagnostic) Manufacturing","slug":"biological-product-except-diagnostic-manufacturing"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Engineer, Process Sciences - Upstream","description":"Encoded Therapeutics is a clinical-stage genetic medicines company developing potentially disease-modifying therapies to improve the lives of people with severe CNS disorders. Our proprietary vector engineering approach combines novel regulatory elements and payloads with AAV vectors to unlock innovative solutions for debilitating, intractable CNS conditions. At the forefront is our flagship clinical program, ETX101 for Dravet syndrome, which targets the underlying cause of the disorder to enable highly selective upregulation ofSCN1Afor potentially long-lasting benefit. In parallel, we are advancing a pipeline of potentially best-in-class programs to address significant unmet needs across both monogenic and prevalent CNS conditions. For more information, please visit www.encoded.com.\nWe are recruiting an Engineer, Process Sciences to join our team. This is a unique opportunity to work at the intersection of genomics and therapeutics and participate in the development of a diverse therapeutic pipeline driven by a transformative core technology. The successful candidate will work well across multiple projects in a fast-paced and dynamic environment.\nResponsibilities Design, execute, and analyze small-scale studies supporting the development of two at-scale products and Encoded’s pipeline products\nServe as an engineer responsible for pre-clinical and clinical manufacturing for AAV projects and plasmid manufacturing; including upstream, downstream, fill finish, and drug device\nFacilitate Encoded’s technology transfer of manufacturing processes to non-GMP/GMP internal and external sites of manufacturing\nProvide person-in-plant support of GMP (clinical and commercial) manufacturing as required at internal and external sites of manufacturing\nWork with cross-functional teams to develop tools/templates to support tech transfer business processes\nRequirements B.S or M.S. in a relevant area of specialization (biochemical engineering, chemical engineering, biological sciences, virology, molecular biology, or biochemistry)\nAt least 3 years of industry experience or equivalent educational experience\nAt least 1 year of industry experience in MSAT/PD/Process Sciences role preferred\nExtensive working knowledge of modern laboratory procedures and knowledge of cGMP is a must\nAbility to independently design, execute, and analyze small-scale cell culture studies (cell expansion, single-use bioreactors, and harvest/clarification) is a must\nMust be a team player and exhibit a willingness to meet project timelines\nStrong verbal and written skills are required as well as effective interpersonal, technical, and troubleshooting skills\nOutstanding planning, organization, and multitasking skills\nExperience with gene therapy processes is strongly preferred\nBenefits Comprehensive benefits package, including competitive employer premium contributions\nMeaningful stock option grants\nPTO, sick time, and holiday pay\nGenerous Parental Leave program\nPre-tax medical and dependent care programs\nSTD, LTD, Life and AD&D\nProfessional development opportunities\nTeam-building events\nStocked micro-kitchen with drinks and snacks\nWellness Resources\nEncoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind.\nEncoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment.\nAll employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate.\nEncoded will not tolerate discrimination or harassment based on any of these characteristics.\nEncoded encourages applicants of all ages.\n\n#J-18808-Ljbffr","datePosted":"2026-10-04T03:34:00.777Z","dateModified":"2026-10-04T03:34:00.777Z","hiringOrganization":{"@type":"Organization","name":"Encoded","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Morrisville","addressRegion":"NC","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"8a44e431e4f219d971b0753b"},"url":"https://jobsearcher.com/jobs/8a44e431e4f219d971b0753b"}}