{"schemaVersion":"jobsearcher.job.v1","id":"710760bec51d6868fe1fe329","url":"https://jobsearcher.com/jobs/710760bec51d6868fe1fe329","canonicalUrl":"https://jobsearcher.com/jobs/710760bec51d6868fe1fe329","title":"Director, Statistical Programming","description":"The Opportunity\nMaze is looking for a Director of Statistical Programming, who will help shape the data foundation of our clinical development programs. In this role you'll collaborate closely with colleagues across Biostatistics, Clinical Data Management, Clinical Operations, and Regulatory Affairs, and oversee external vendors to keep our studies rigorous, high-quality, and ready for regulatory review.\nYou'll report to the Vice President of Biometrics and lead the strategy and day-to-day execution of statistical programming across multiple clinical studies. Your leadership will ensure we deliver reliable, efficient, and regulatory-compliant programming outputs that drive smarter decisions and advance our therapeutic programs.\nThe Impact You'll Have\nDefine and implement statistical programming strategy, standards, and best practices across development programs.\nLead the design, development, validation, and maintenance of SAS macros, scripts, and applications supporting clinical data analysis, reporting, and regulatory deliverables (e.g., SDTM, ADaM datasets, TLFs).\nEnsure programming infrastructure is robust, scalable, and compliant with regulatory standards (e.g., FDA 21 CFR Part 11, GxP), and supports reproducibility and audit readiness.\nDrive automation and standardization of programming workflows to improve efficiency and consistency across studies.\nPartner closely with Biostatistics, Clinical Data Management, Regulatory Affairs, and IT to define programming requirements, align on analysis/reporting deliverables, and ensure data integrity.\nRepresent the statistical programming function in cross-functional meetings and strategic initiatives.\nManage CROs and external programming vendors, including scope, timelines, quality, and budget oversight.\nSupport outsourcing strategy and vendor selection\nAs a Director, we also expect you to demonstrate the following Leadership Competencies:\nCommunication and Influence\nBuilds communication channels across Maze for sharing information.\nInfluences Senior Management decisions through persuasive arguments.\nRespectfully addresses differing opinions leading to support of decisions.\nTeamwork and Collaboration\nChampions partnerships and connections across Maze.\nProactively addresses issues that could result in breakdown of team relationships.\nSpotlights team and individual contributions in public forums.\nExecution and Results\nAddresses gaps and leverages strengths to get best results.\nMaintains a steadying presence and clarifies priorities during change.\nAnticipates and removes barriers that put functional/corporate goals at risk.\nDevelop Others and Self\nRemove barriers to staff development and empowers them to make their own decisions.\nStays current on industry trends and keeps direct-reports prepared and responsive.\nWhat We're Looking For\nAn advanced degree in Statistics, Computer Science, Mathematics, or related discipline\nMaster's degree with 10+ years of experience, or Ph.D. with 8+ years of experience\nA track record of leading statistical programming efforts across multiple clinical studies or regulatory submissions.\nStrong decision-making skills and the ability to guide teams through ambiguity while influencing across project teams.\nA collaborative leadership style that emphasizes mentorship, knowledge sharing, and developing others.\nDeep technical expertise in statistical programming for clinical research, with familiarity in CDISC standards, submission‑ready deliverables, and modern programming best practices.\nThis role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week.\nAbout Maze Therapeutics\nMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. The company's pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease. Maze is based in South San Francisco.\nOur People\nMaze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.\nOur Core Values\nFurther Together – Our path is paved with challenges, but with resilience and a team-first mentality, we'll achieve our mission.\nImpact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.\nStand True – Our integrity is foundational; it guides us no matter the obstacle.\nThe expected annual salary range for employees located in the San Francisco Bay Area is $229,000 - $279,000. Additionally, this position is eligible for an annual performance bonus.\nMaze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.\nMaze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.\n\n#LI-Hybrid","company":"Mazetherapeutics","rawCompany":"mazetherapeutics","city":"Millbrae","state":"CA","isRemote":false,"isActive":false,"createdAt":"2026-04-14T11:14:28.801Z","occupations":[{"code":"15-2041.01","title":"Biostatisticians","slug":"biostatisticians"},{"code":"11-9121.00","title":"Natural Sciences Managers","slug":"natural-sciences-managers"},{"code":"15-2041.00","title":"Statisticians","slug":"statisticians"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"541690","title":"Other Scientific and Technical Consulting Services","slug":"other-scientific-and-technical-consulting-services"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Director, Statistical Programming","description":"The Opportunity\nMaze is looking for a Director of Statistical Programming, who will help shape the data foundation of our clinical development programs. In this role you'll collaborate closely with colleagues across Biostatistics, Clinical Data Management, Clinical Operations, and Regulatory Affairs, and oversee external vendors to keep our studies rigorous, high-quality, and ready for regulatory review.\nYou'll report to the Vice President of Biometrics and lead the strategy and day-to-day execution of statistical programming across multiple clinical studies. Your leadership will ensure we deliver reliable, efficient, and regulatory-compliant programming outputs that drive smarter decisions and advance our therapeutic programs.\nThe Impact You'll Have\nDefine and implement statistical programming strategy, standards, and best practices across development programs.\nLead the design, development, validation, and maintenance of SAS macros, scripts, and applications supporting clinical data analysis, reporting, and regulatory deliverables (e.g., SDTM, ADaM datasets, TLFs).\nEnsure programming infrastructure is robust, scalable, and compliant with regulatory standards (e.g., FDA 21 CFR Part 11, GxP), and supports reproducibility and audit readiness.\nDrive automation and standardization of programming workflows to improve efficiency and consistency across studies.\nPartner closely with Biostatistics, Clinical Data Management, Regulatory Affairs, and IT to define programming requirements, align on analysis/reporting deliverables, and ensure data integrity.\nRepresent the statistical programming function in cross-functional meetings and strategic initiatives.\nManage CROs and external programming vendors, including scope, timelines, quality, and budget oversight.\nSupport outsourcing strategy and vendor selection\nAs a Director, we also expect you to demonstrate the following Leadership Competencies:\nCommunication and Influence\nBuilds communication channels across Maze for sharing information.\nInfluences Senior Management decisions through persuasive arguments.\nRespectfully addresses differing opinions leading to support of decisions.\nTeamwork and Collaboration\nChampions partnerships and connections across Maze.\nProactively addresses issues that could result in breakdown of team relationships.\nSpotlights team and individual contributions in public forums.\nExecution and Results\nAddresses gaps and leverages strengths to get best results.\nMaintains a steadying presence and clarifies priorities during change.\nAnticipates and removes barriers that put functional/corporate goals at risk.\nDevelop Others and Self\nRemove barriers to staff development and empowers them to make their own decisions.\nStays current on industry trends and keeps direct-reports prepared and responsive.\nWhat We're Looking For\nAn advanced degree in Statistics, Computer Science, Mathematics, or related discipline\nMaster's degree with 10+ years of experience, or Ph.D. with 8+ years of experience\nA track record of leading statistical programming efforts across multiple clinical studies or regulatory submissions.\nStrong decision-making skills and the ability to guide teams through ambiguity while influencing across project teams.\nA collaborative leadership style that emphasizes mentorship, knowledge sharing, and developing others.\nDeep technical expertise in statistical programming for clinical research, with familiarity in CDISC standards, submission‑ready deliverables, and modern programming best practices.\nThis role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week.\nAbout Maze Therapeutics\nMaze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. The company is advancing a pipeline using its Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process it refers to as variant functionalization. The company's pipeline is led by two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease. Maze is based in South San Francisco.\nOur People\nMaze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.\nOur Core Values\nFurther Together – Our path is paved with challenges, but with resilience and a team-first mentality, we'll achieve our mission.\nImpact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.\nStand True – Our integrity is foundational; it guides us no matter the obstacle.\nThe expected annual salary range for employees located in the San Francisco Bay Area is $229,000 - $279,000. Additionally, this position is eligible for an annual performance bonus.\nMaze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.\nMaze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.\n\n#LI-Hybrid","datePosted":"2026-04-14T11:14:28.801Z","dateModified":"2026-04-14T11:14:28.801Z","hiringOrganization":{"@type":"Organization","name":"Mazetherapeutics","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Millbrae","addressRegion":"CA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"710760bec51d6868fe1fe329"},"url":"https://jobsearcher.com/jobs/710760bec51d6868fe1fe329"}}