{"schemaVersion":"jobsearcher.job.v1","id":"5dca79b3ee8fa8349e7cf8c2","url":"https://jobsearcher.com/jobs/5dca79b3ee8fa8349e7cf8c2","canonicalUrl":"https://jobsearcher.com/jobs/5dca79b3ee8fa8349e7cf8c2","title":"Process Development Scientist- Downstream","description":"*TITLE: *Process Development Scientist- Downstream\n\n*LOCATION*: Frederick, MD\n\n*REQ#:* 22-001\n\n*Overview*: Jecho Laboratories, Inc. (Jecho) is a biopharmaceutical company developing bio-similar, innovative therapeutic biologics, including therapeutic monoclonal antibodies, cytokines, immunotoxins, and vaccines to address a broad range of diseases as well as treatment of cancer and infectious disease. The company headquarter is located in Frederick Maryland, USA.\n\nWe are seeking a Process Development Scientist to join our R&D team in Frederick, MD. Qualified individuals will execute small-scale downstream process development and analytical studies. The ideal candidate will exercise appropriate technical judgment in the design, execution, and interpretation of experiments. The candidate will receive general instructions from a supervisor for routine work and assignments. The candidate is expected to be eager to learn, highly productive, well organized, and self-motivated.\n\n*Essential Job Functions*:\n\n· Design and conduct experiments in protein and DNA/RNA therapeutics recovery and purification process development, and formulation development with an interdisciplinary approach spanning molecular and protein biology, protein and biomolecule separation, chemical and biochemical engineering, etc.\n\n· Perform column chromatography and various other routine physical and biochemical analysis on biological products, such as HPLC, SDS-PAGE, UF/DF, Western Blot, and ELISA.\n\n· Perform small-scale _E. coli _fermentation or mammalian cell bioreactor to generate protein materials for evaluation and characterization.\n\n· Design and perform protein stability analyses via protein size, conformation, homogeneity, and/or potency analyses.\n\n· Optimize protein formulation and/or storage conditions to improve protein stability.\n\n· Work with Discovery, Upstream Process Development, and Analytical Development to support material generation, design evaluation, cell line selection, product characterization and analyses.\n\n· Generate and maintain experimental data in a highly organized manner.\n\n· Prepare technical reports and present data and analyses, perform and support technology transfer activities, and report project status to senior scientists and management.\n\n*Minimum Requirements*:\n\n· A Ph.D. degree in biological or pharmaceutical science, biochemistry, bioengineering, human nutrition, or related fields.\n\n· 0-3 years’ experience in post-doctoral training or the pharmaceutical or biotechnology industry.\n\n· An in-depth understanding of antibody and recombinant protein structure and purification mechanisms.\n\n· Extensive hands-on experience with protein recovery and purification and analytical methods.\n\n· Working experience with biophysical characterization, product stability, and related microscopic and spectroscopic analysis techniques is a plus.\n\n· Extensive working experience with drug formulation, stability analysis, and delivery technologies.\n\n· Exhibited ability to propose, design, execute experiments and deliver a project in a timely manner with high quality.\n\n· Ability to work effectively in a team. Motivated and willing to work on a variety of tasks.\n\n· Experience working with DNA and/or RNA extraction, purification, and related processes is a plus.\n\n· Experience with model animals and surgical procedures is a plus.\n\nThis position may require you standing/sitting/walking in the lab for routinely 8 hours and sometimes up to 12 hours, as well as lifting weight up to 30 pounds.\n\n*Compensation:*\n\n· Jecho offers a competitive salary and excellent benefits package, including health insurance, dental/vision insurance, short-term and long-term disability insurance, and 401(k) retirement plan.\n\n· Jecho is an equal opportunity employer.\n\nThe job description is subject to change by the employer as the organizational needs and requirements of the job change.\n\nJob Type: Full-time\n\nPay: $75,000.00 - $100,000.00 per year\n\nBenefits:\n* 401(k)\n* 401(k) matching\n* Dental insurance\n* Health insurance\n* Health savings account\n* Paid time off\n* Parental leave\n* Referral program\n* Tuition reimbursement\n* Vision insurance\nSchedule:\n* Monday to Friday\n\nWork Location: In person","company":"Jecho Laboratories","rawCompany":"jecho laboratories","city":"Frederick","state":"MD","isRemote":false,"isActive":false,"createdAt":"2026-09-01T08:59:26.255Z","occupations":[{"code":"19-1021.00","title":"Biochemists and Biophysicists","slug":"biochemists-and-biophysicists"},{"code":"19-1029.02","title":"Molecular and Cellular Biologists","slug":"molecular-and-cellular-biologists"},{"code":"19-1042.00","title":"Medical Scientists, Except Epidemiologists","slug":"medical-scientists-except-epidemiologists"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"541380","title":"Testing Laboratories and Services","slug":"testing-laboratories-and-services"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Process Development Scientist- Downstream","description":"*TITLE: *Process Development Scientist- Downstream\n\n*LOCATION*: Frederick, MD\n\n*REQ#:* 22-001\n\n*Overview*: Jecho Laboratories, Inc. (Jecho) is a biopharmaceutical company developing bio-similar, innovative therapeutic biologics, including therapeutic monoclonal antibodies, cytokines, immunotoxins, and vaccines to address a broad range of diseases as well as treatment of cancer and infectious disease. The company headquarter is located in Frederick Maryland, USA.\n\nWe are seeking a Process Development Scientist to join our R&D team in Frederick, MD. Qualified individuals will execute small-scale downstream process development and analytical studies. The ideal candidate will exercise appropriate technical judgment in the design, execution, and interpretation of experiments. The candidate will receive general instructions from a supervisor for routine work and assignments. The candidate is expected to be eager to learn, highly productive, well organized, and self-motivated.\n\n*Essential Job Functions*:\n\n· Design and conduct experiments in protein and DNA/RNA therapeutics recovery and purification process development, and formulation development with an interdisciplinary approach spanning molecular and protein biology, protein and biomolecule separation, chemical and biochemical engineering, etc.\n\n· Perform column chromatography and various other routine physical and biochemical analysis on biological products, such as HPLC, SDS-PAGE, UF/DF, Western Blot, and ELISA.\n\n· Perform small-scale _E. coli _fermentation or mammalian cell bioreactor to generate protein materials for evaluation and characterization.\n\n· Design and perform protein stability analyses via protein size, conformation, homogeneity, and/or potency analyses.\n\n· Optimize protein formulation and/or storage conditions to improve protein stability.\n\n· Work with Discovery, Upstream Process Development, and Analytical Development to support material generation, design evaluation, cell line selection, product characterization and analyses.\n\n· Generate and maintain experimental data in a highly organized manner.\n\n· Prepare technical reports and present data and analyses, perform and support technology transfer activities, and report project status to senior scientists and management.\n\n*Minimum Requirements*:\n\n· A Ph.D. degree in biological or pharmaceutical science, biochemistry, bioengineering, human nutrition, or related fields.\n\n· 0-3 years’ experience in post-doctoral training or the pharmaceutical or biotechnology industry.\n\n· An in-depth understanding of antibody and recombinant protein structure and purification mechanisms.\n\n· Extensive hands-on experience with protein recovery and purification and analytical methods.\n\n· Working experience with biophysical characterization, product stability, and related microscopic and spectroscopic analysis techniques is a plus.\n\n· Extensive working experience with drug formulation, stability analysis, and delivery technologies.\n\n· Exhibited ability to propose, design, execute experiments and deliver a project in a timely manner with high quality.\n\n· Ability to work effectively in a team. Motivated and willing to work on a variety of tasks.\n\n· Experience working with DNA and/or RNA extraction, purification, and related processes is a plus.\n\n· Experience with model animals and surgical procedures is a plus.\n\nThis position may require you standing/sitting/walking in the lab for routinely 8 hours and sometimes up to 12 hours, as well as lifting weight up to 30 pounds.\n\n*Compensation:*\n\n· Jecho offers a competitive salary and excellent benefits package, including health insurance, dental/vision insurance, short-term and long-term disability insurance, and 401(k) retirement plan.\n\n· Jecho is an equal opportunity employer.\n\nThe job description is subject to change by the employer as the organizational needs and requirements of the job change.\n\nJob Type: Full-time\n\nPay: $75,000.00 - $100,000.00 per year\n\nBenefits:\n* 401(k)\n* 401(k) matching\n* Dental insurance\n* Health insurance\n* Health savings account\n* Paid time off\n* Parental leave\n* Referral program\n* Tuition reimbursement\n* Vision insurance\nSchedule:\n* Monday to Friday\n\nWork Location: In person","datePosted":"2026-09-01T08:59:26.255Z","dateModified":"2026-09-01T08:59:26.255Z","hiringOrganization":{"@type":"Organization","name":"Jecho Laboratories","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Frederick","addressRegion":"MD","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"5dca79b3ee8fa8349e7cf8c2"},"url":"https://jobsearcher.com/jobs/5dca79b3ee8fa8349e7cf8c2"}}