Scientist - Tech Transfer

Scientist - Tech Transfer ( Onsite in Wilsonville, OR)Job DescriptionWe are seeking a Scientist to join our Tech Transfer team, focused on advancing and scaling synthetic biology workflows across DNA-based and mammalian cell culture systems. This role sits at the interface of R&D and production, where you will drive the successful transfer of new products and processes into high-throughput manufacturing environments.You will play a key role in developing, optimizing, and troubleshooting workflows spanning molecular biology and mammalian cell culture systems, ensuring processes are robust, scalable, and production-ready. This includes hands-on experimental work, cross-functional collaboration, and enabling operational teams through training, technical guidance, and documentation.This is a highly collaborative role partnering with teams across operations, automation engineering, and bioinformatics to translate innovation into reliable production processes. A key component of this work will be designing processes with automation in mind, enabling deployment across a diverse suite of liquid handling platforms to support scalable and standardized manufacturing.We are looking for someone who combines strong experimental rigor with practical problem-solving, and who is equally comfortable working at the bench and thinking strategically about process improvement. Experience across both DNA technologies (e.g., NGS, cloning) and mammalian cell culture/protein expression systems is highly valued.If you enjoy working in a fast-paced, multidisciplinary environment where you can directly impact how products are built and delivered at scale, this role offers broad exposure to cutting-edge synthetic biology platforms and technologies.Key ResponsibilitiesDesign and execute experiments to develop, optimize, and scale production workflows for synthetic biology products, including DNA and mammalian cell-based protein expression systemsDrive process improvements by analyzing complex datasets and translating findings into actionable changes across workflowsLead technical transfer of new products and processes into production, ensuring robustness, reproducibility, and scalabilityAuthor and maintain technical documentation, including SOPs, validation protocols, and training materials to support manufacturing teamsAct as a technical subject matter expert, representing R&D/PD in cross-functional meetings and contributing to project strategy and decision-makingCollaborate cross-functionally with operations, automation, and bioinformatics teams to troubleshoot issues and implement solutionsApply scientific literature and domain expertise to inform experimental design, process development, and strategic directionMaintain clear and accurate documentation of experimental work and results using electronic lab notebooksMentor and train team members and operators on newly developed processes and workflowsQualifications And Required SkillsPhD in Molecular Biology, Biochemistry, or related field; or Master’s with 2–5+ years of industry experience; or Bachelor’s with 5+ years of relevant experienceStrong foundation in molecular biology techniques, including DNA/RNA purification, PCR/qPCR, and molecular cloningHands-on experience developing and optimizing mammalian cell culture systems for protein expression (e.g., HEK, CHO)Experience designing expression constructs and optimizing systems for yield, solubility, and activity across host platformsProven ability to develop and optimize upstream and downstream workflows, including transfection and protein purification strategiesDemonstrated experience in experimental design, data analysis, troubleshooting, and method development in complex biological systemsStrong attention to detail and ability to translate experimental outcomes into scalable process improvementsSolid scientific judgment and ability to independently drive technical decisionsPreferred SkillsExperience with next-generation sequencing (NGS) workflows, library preparation, and/or data analysisFamiliarity with high-throughput workflows and laboratory automation systems (e.g., liquid handlers)Programming or data analysis experience (e.g., Python, SQL, JSON) for handling large datasetsProven ability to manage multiple priorities in a fast-paced environmentStrong collaboration and communication skills, with experience working across multidisciplinary teamsExperience mentoring, training, or onboarding team membersDemonstrated problem-solving skills and a proactive, solution-oriented mindsetSelf-motivated with a commitment to continuous learning and staying current with scientific advancementsAbout Twist BioscienceTwist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.At Twist Bioscience, we serve people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals, and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.The base cash compensation for this Oregon-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.