Sr. Director, Medical Affairs

We are partnering with a global biopharmaceutical company to identify a Senior Director, Medical Affairs, to lead the US Medical strategy within the rare hematology disease area. This is a highly visible leadership opportunity for an experienced Medical Affairs professional who brings strong scientific credibility, strategic leadership, and the ability to influence across a complex, matrixed organization. The individual in this role will serve as the US medical and scientific lead for the therapeutic area, guiding the development and execution of Medical Affairs strategy, shaping field medical priorities, and partnering closely with Commercial, Market Access, Regulatory, Safety, Scientific Affairs, and Clinical Development. This person will also play an important external role, building trusted relationships with key opinion leaders and representing the organization across the broader medical and scientific community. Key Responsibilities Lead the US Medical Affairs team for the assigned disease area, including Medical Directors, Medical Scientists, and Field Medical leadership Develop and execute annual US Medical plans in alignment with global Medical strategy Adapt and localize global medical content for the US market Serve as the lead US scientific and clinical expert within the therapeutic area Drive the scientific agenda by aligning resources and priorities to the needs of the region Provide strategic direction, coaching, and support to Field Medical leadership to ensure strong alignment between headquarters strategy and field execution Oversee the development and execution of MSL field plans, insight generation priorities, and communication flow between field and headquarters teams Partner cross-functionally with Commercial, Market Access, Regulatory, Safety, and Scientific Affairs to support both patient needs and portfolio objectives Ensure promotional and scientific materials are medically accurate, balanced, data-driven, and appropriate for the intended audience Provide medical input into labeling strategy, regulatory plans, evidence generation activities, and publication planning Represent Medical Affairs in promotional review and other cross-functional governance processes Build and maintain strong relationships with key thought leaders, healthcare professionals, and relevant external stakeholders Represent the organization at congresses, advisory boards, scientific meetings, and other external forums Maintain a strong understanding of disease state, current treatment practices, market dynamics, emerging data, and competitive activity Communicate unmet medical needs, external insights, and evolving trends to internal stakeholders to help shape strategy Foster a high-performing, scientifically credible Medical Affairs team and culture Candidate Profile MD preferred; PhD, PharmD, or other advanced scientific degree required 7+ years of pharmaceutical, biotechnology, or biotherapeutics industry experience Prior leadership experience within Medical Affairs, including team leadership and people management Strong track record of developing and executing Medical Affairs strategy in the US and other key markets Deep understanding of drug development, including clinical development, regulatory strategy, and lifecycle management Experience partnering effectively across Commercial, Market Access, Regulatory, and Field Medical functions Demonstrated success in building and maintaining strong KOL relationships Ability to operate successfully in a global, matrixed, and fast-paced environment Strong communication skills, executive presence, and cross-functional leadership capabilities Therapeutic expertise in hematology, rare disease, or a closely related area is strongly preferred Willingness to travel up to 30% Why This Role This is an opportunity to step into a meaningful Medical Affairs leadership role with broad visibility and influence. The position offers the chance to shape US Medical strategy, lead a team, partner across functions, and engage externally in support of both patients and long-term portfolio success. #J-18808-Ljbffr