{"schemaVersion":"jobsearcher.job.v1","id":"49eec76b0fd6969d0a2ecd1c","url":"https://jobsearcher.com/jobs/49eec76b0fd6969d0a2ecd1c","canonicalUrl":"https://jobsearcher.com/jobs/49eec76b0fd6969d0a2ecd1c","title":"Principal Data Manager","description":"If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.\n\nFull Time Remote, US\n\nSalary Range: $149,000.00 To $175,000.00 Annually\n\nAbout CG Oncology, Inc.\nA re you ready to make a difference in the world and become part of our patient-centered team that is focused on Attacking Bladder Cancer for a Better Tomorrow? At CG Oncology, we believe that by having exceptionally talented individuals on our team who share our passion and enjoy working together, we can truly achieve our Vision and Mission to benefit patients around the world.\n\nEvery day we are making significant advancements across our multiple pipelines and are growing rapidly to meet the needs of our patients who cannot afford to wait to benefit from our novel immunotherapies. Please review this job posting and our Values and if they resonate with you and are what you expect from your organization and team, then we would like to hear from you.\n\nAbout the role\nThe Principal Data Manager is a recognized subject matter expert responsible for providing strategic leadership and oversight for Clinical Data Management (CDM) across multiple clinical programs and studies. This role establishes data management standards, drives organizational best practices, influences cross-functional development strategies, and serves as a key partner to Clinical Development leadership. The Principal Data Manager provides expert oversight of complex clinical trials, vendor partnerships, data governance initiatives, regulatory submission readiness, and process optimization efforts. This individual acts as a mentor and technical leader within the organization, ensuring the delivery of high-quality, compliant, and inspection-ready clinical data that supports corporate development objectives.\n\nEssential Functions\n\nLeads all clinical data management activities for assigned clinical studies from start-up through database lock and study closeout.\n\nServes as the primary Data Management representative on cross-functional study teams.\n\nDevelops and executes Data Management Plans (DMPs), Data Review Plans, and study-specific data management strategies.\n\nProvides strategic input into protocol development to ensure data collection requirements support study objectives and regulatory expectations.\n\nIdentifies and mitigates study-level data risks and escalates issues appropriately.\n\nStrategic Leadership\n\nLeads data management strategy across multiple programs and therapeutic areas.\n\nEstablishes and maintains departmental standards, governance frameworks, and data quality metrics.\n\nProvides strategic input into clinical development planning and regulatory submission strategies.\n\nServes as the senior Data Management representative for executive and cross-functional governance committees.\n\nEvaluates and implements emerging technologies and industry best practices.\n\nDatabase Design & Data Quality\n\nLeads CRF/eCRF design and review in collaboration with Clinical Operations, Medical, Biostatistics, Regulatory, and Safety teams.\n\nOversees database build activities, edit check specifications, derivation requirements, and data validation rules.\n\nLeads User Acceptance Testing (UAT) and approves database releases. .\n\nEstablishes and drives data review, cleaning, reconciliation, and quality control activities to ensure inspection-ready datasets.\n\nOversees query management and data cleaning efforts to support study milestones and database lock timelines.\n\nProvides oversight of CROs, EDC vendors, central laboratories, imaging vendors, and other external data providers.\n\nReviews vendor deliverables, performance metrics, timelines, and quality indicators.\n\nLeads development and maintenance of Data Transfer Agreements (DTAs), vendor specifications, and reconciliation processes.\n\nEnsures vendor compliance with study requirements, SOPs, GCP, and applicable regulations.\n\nProcess Improvement & Standards\n\nContributes to the development and continuous improvement of departmental SOPs, work instructions, templates, and standards.\n\nChampions implementation of CDISC and industry best practices for data collection and management.\n\nSupports inspection readiness and audit preparation activities.\n\nDrives process optimization initiatives to improve efficiency, data quality, and study execution.\n\nProvides guidance, mentorship, and training to Clinical Data Managers and junior team members.\n\nServes as a subject matter expert (SME) for Clinical Data Management processes and systems.\n\nFacilitates knowledge sharing and promotes consistent application of data management standards across studies.\n\nQualifications\n\nBS/BA in a relevant scientific discipline.\n\n12+ years of progressive Clinical Data Management experience in biotechnology, pharmaceutical, or CRO environments.\n\nExtensive experience leading Data Management activities across Phase I–III clinical trials.\n\nDemonstrated experience leading global, multi-study, and submission-enabling programs.\n\nProven experience developing departmental standards, SOPs, and governance processes.\n\nSignificant experience managing strategic vendor relationships\n\nTotal Rewards\nCG Oncology offers very competitive and comprehensive Total Rewards, helping to support and reward our global team of high-performing employees focused on developing bladder-saving therapeutics for patients afflicted with bladder cancer.\n\nHIGHLY COMPETITIVE SALARIES\n\nANNUAL PERFORMANCE/MERIT REVIEWS\n\nANNUAL PERFORMANCE BONUSES\n\nEQUITY\n\nSPECIAL RECOGNITION\n\nIn addition to our Total Rewards, CG Oncology offers a variety of Well-Being Benefits to meet the majority of the needs of our unique and growing workforce. These benefits are designed to support our team to achieve a healthy balance between work and their personal lives to remain refreshed, engaged, and creating an environment where each person can find a deeper meaning and purpose in their work.\n\nWell-Being Benefits eligibility begins the 1st of the month after hire. While a majority of these benefits are for our US-based workforce, we continue to assess comparable levels of benefits for our international team members that are aligned with country-specific regulations and their national programs offered.\n\nFULLY REMOTE WORK ENVIRONMENT\n\nREST AND RECHARGE BENEFITS - Unlimited Flexible Time Off\n\nHOLIDAYS –In 2026 we will observe 14 holidays\n\nRETIREMENT – 401K with 100% company Safe Harbor match up to 4% of base salary\n\nHEALTH SPENDING ACCOUNTS - HSA (with Annual Company Contribution), FSA, FSA-DC\n\nILLNESS & DISABILITY PROTECTION – Company Paid LTD Coverage + Voluntary Plans\n\nLIFE INSURANCE – Company Paid 1 x base salary + Voluntary Plans\n\nADDITIONAL EXCLUSIVE BENEFITS – Voluntary Legal, Pet, Plus More\n\nCG Oncology is an Equal Opportunity Employer\nAll applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. At CG Oncology, we are building a community of intelligent and passionate team members that share our Vision, Mission and Values, and while the biotechnology space can feel limited in BIPOC, non-binary and even female representation, we endeavor to make hiring decisions that will continue to grow and support our team in the direction of maintaining cultural diversity and sustainability.\n\n#J-18808-Ljbffr","company":"Evolving Solution Services","rawCompany":"evolving solution services","city":"New York","state":"NY","isRemote":false,"isActive":false,"createdAt":"2026-09-12T04:17:45.918Z","occupations":[{"code":"15-2051.02","title":"Clinical Data Managers","slug":"clinical-data-managers"},{"code":"15-1243.01","title":"Data Warehousing Specialists","slug":"data-warehousing-specialists"},{"code":"11-3021.00","title":"Computer and Information Systems Managers","slug":"computer-and-information-systems-managers"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"541512","title":"Computer Systems Design Services","slug":"computer-systems-design-services"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Principal Data Manager","description":"If you are unable to complete this application due to a disability, contact this employer to ask for an accommodation or an alternative application process.\n\nFull Time Remote, US\n\nSalary Range: $149,000.00 To $175,000.00 Annually\n\nAbout CG Oncology, Inc.\nA re you ready to make a difference in the world and become part of our patient-centered team that is focused on Attacking Bladder Cancer for a Better Tomorrow? At CG Oncology, we believe that by having exceptionally talented individuals on our team who share our passion and enjoy working together, we can truly achieve our Vision and Mission to benefit patients around the world.\n\nEvery day we are making significant advancements across our multiple pipelines and are growing rapidly to meet the needs of our patients who cannot afford to wait to benefit from our novel immunotherapies. Please review this job posting and our Values and if they resonate with you and are what you expect from your organization and team, then we would like to hear from you.\n\nAbout the role\nThe Principal Data Manager is a recognized subject matter expert responsible for providing strategic leadership and oversight for Clinical Data Management (CDM) across multiple clinical programs and studies. This role establishes data management standards, drives organizational best practices, influences cross-functional development strategies, and serves as a key partner to Clinical Development leadership. The Principal Data Manager provides expert oversight of complex clinical trials, vendor partnerships, data governance initiatives, regulatory submission readiness, and process optimization efforts. This individual acts as a mentor and technical leader within the organization, ensuring the delivery of high-quality, compliant, and inspection-ready clinical data that supports corporate development objectives.\n\nEssential Functions\n\nLeads all clinical data management activities for assigned clinical studies from start-up through database lock and study closeout.\n\nServes as the primary Data Management representative on cross-functional study teams.\n\nDevelops and executes Data Management Plans (DMPs), Data Review Plans, and study-specific data management strategies.\n\nProvides strategic input into protocol development to ensure data collection requirements support study objectives and regulatory expectations.\n\nIdentifies and mitigates study-level data risks and escalates issues appropriately.\n\nStrategic Leadership\n\nLeads data management strategy across multiple programs and therapeutic areas.\n\nEstablishes and maintains departmental standards, governance frameworks, and data quality metrics.\n\nProvides strategic input into clinical development planning and regulatory submission strategies.\n\nServes as the senior Data Management representative for executive and cross-functional governance committees.\n\nEvaluates and implements emerging technologies and industry best practices.\n\nDatabase Design & Data Quality\n\nLeads CRF/eCRF design and review in collaboration with Clinical Operations, Medical, Biostatistics, Regulatory, and Safety teams.\n\nOversees database build activities, edit check specifications, derivation requirements, and data validation rules.\n\nLeads User Acceptance Testing (UAT) and approves database releases. .\n\nEstablishes and drives data review, cleaning, reconciliation, and quality control activities to ensure inspection-ready datasets.\n\nOversees query management and data cleaning efforts to support study milestones and database lock timelines.\n\nProvides oversight of CROs, EDC vendors, central laboratories, imaging vendors, and other external data providers.\n\nReviews vendor deliverables, performance metrics, timelines, and quality indicators.\n\nLeads development and maintenance of Data Transfer Agreements (DTAs), vendor specifications, and reconciliation processes.\n\nEnsures vendor compliance with study requirements, SOPs, GCP, and applicable regulations.\n\nProcess Improvement & Standards\n\nContributes to the development and continuous improvement of departmental SOPs, work instructions, templates, and standards.\n\nChampions implementation of CDISC and industry best practices for data collection and management.\n\nSupports inspection readiness and audit preparation activities.\n\nDrives process optimization initiatives to improve efficiency, data quality, and study execution.\n\nProvides guidance, mentorship, and training to Clinical Data Managers and junior team members.\n\nServes as a subject matter expert (SME) for Clinical Data Management processes and systems.\n\nFacilitates knowledge sharing and promotes consistent application of data management standards across studies.\n\nQualifications\n\nBS/BA in a relevant scientific discipline.\n\n12+ years of progressive Clinical Data Management experience in biotechnology, pharmaceutical, or CRO environments.\n\nExtensive experience leading Data Management activities across Phase I–III clinical trials.\n\nDemonstrated experience leading global, multi-study, and submission-enabling programs.\n\nProven experience developing departmental standards, SOPs, and governance processes.\n\nSignificant experience managing strategic vendor relationships\n\nTotal Rewards\nCG Oncology offers very competitive and comprehensive Total Rewards, helping to support and reward our global team of high-performing employees focused on developing bladder-saving therapeutics for patients afflicted with bladder cancer.\n\nHIGHLY COMPETITIVE SALARIES\n\nANNUAL PERFORMANCE/MERIT REVIEWS\n\nANNUAL PERFORMANCE BONUSES\n\nEQUITY\n\nSPECIAL RECOGNITION\n\nIn addition to our Total Rewards, CG Oncology offers a variety of Well-Being Benefits to meet the majority of the needs of our unique and growing workforce. These benefits are designed to support our team to achieve a healthy balance between work and their personal lives to remain refreshed, engaged, and creating an environment where each person can find a deeper meaning and purpose in their work.\n\nWell-Being Benefits eligibility begins the 1st of the month after hire. While a majority of these benefits are for our US-based workforce, we continue to assess comparable levels of benefits for our international team members that are aligned with country-specific regulations and their national programs offered.\n\nFULLY REMOTE WORK ENVIRONMENT\n\nREST AND RECHARGE BENEFITS - Unlimited Flexible Time Off\n\nHOLIDAYS –In 2026 we will observe 14 holidays\n\nRETIREMENT – 401K with 100% company Safe Harbor match up to 4% of base salary\n\nHEALTH SPENDING ACCOUNTS - HSA (with Annual Company Contribution), FSA, FSA-DC\n\nILLNESS & DISABILITY PROTECTION – Company Paid LTD Coverage + Voluntary Plans\n\nLIFE INSURANCE – Company Paid 1 x base salary + Voluntary Plans\n\nADDITIONAL EXCLUSIVE BENEFITS – Voluntary Legal, Pet, Plus More\n\nCG Oncology is an Equal Opportunity Employer\nAll applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. At CG Oncology, we are building a community of intelligent and passionate team members that share our Vision, Mission and Values, and while the biotechnology space can feel limited in BIPOC, non-binary and even female representation, we endeavor to make hiring decisions that will continue to grow and support our team in the direction of maintaining cultural diversity and sustainability.\n\n#J-18808-Ljbffr","datePosted":"2026-09-12T04:17:45.918Z","dateModified":"2026-09-12T04:17:45.918Z","hiringOrganization":{"@type":"Organization","name":"Evolving Solution Services","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"New York","addressRegion":"NY","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"49eec76b0fd6969d0a2ecd1c"},"url":"https://jobsearcher.com/jobs/49eec76b0fd6969d0a2ecd1c"}}