{"schemaVersion":"jobsearcher.job.v1","id":"455b2284dc7709db489f4671","url":"https://jobsearcher.com/jobs/455b2284dc7709db489f4671","canonicalUrl":"https://jobsearcher.com/jobs/455b2284dc7709db489f4671","title":"Lead Full Stack Developer (C#/.NET)","description":"Theradex Systems, Inc.\r\nTheradex is an Equal Opportunity Employer.\r\nUS-NJ-Princeton | US\r\nID 2026-1426\r\nCategory Information Technology\r\nType Full Time\r\nWho We Are Celebrating 40+ years!\r\nTheradex Oncology is a full-service CRO specializing in oncology. The company manages global oncology trials and programs. The company was founded in 1982 working with the National Cancer Institute, which led to its expansion to working with industry sponsors developing cancer therapeutics. As a service-based company we support both domestic and international sponsors in the conduct of both early and late phase trials.\r\nWhat You'll Do Location: Princeton, NJ (Hybrid – Onsite 3 days/week preferred) - Will consider regionally remote candidates.\r\nAs part of Theradex Oncology, you will have the opportunity to work with one of the largest professional teams focused solely on the development of cancer therapies. Cancer research continues to evolve as new therapies and therapeutic approaches are discovered, as part of the team you will work to support our sponsors in the development of these therapies. Theradex Oncology is an environment for highly motivated individuals who want to make a difference.\r\nAbout the Role We are seeking a Lead Full stack developer responsible for designing, building and operating end-to-end web applications and data driven solutions that support clinical trial operations. This is a hands-on technical leadership role, combining senior individual contributor responsibilities with mentoring and guiding other developers on modern practices. This role requires recent hands-on experience owning technical solutions and driving projects forward while maintaining Full Stack Development responsibilities.\r\nKey Responsibilities Oversees application development team's technical delivery across all projects while remaining a hands-on Full Stack Developer.\r\nDesign and implement scalable, secure frontend and backend components, including APIs, services and UI workflows, following clean architecture and solid principles.\r\nEmbed application security best practices into the software development lifecycle, including securing code, code scanning, dependency management, and remediation of vulnerability identified through AppSec tools.\r\nCollaborate with product owners, technical analysts, project managers, platform engineering and analytics teams to translate complex business needs into practical technical solutions.\r\nOwn technical solutions end to end: architecture, implementation, testing, deployment, and support.\r\nEstablish and champion coding standards, automated testing, and CI/CD pipelines to improve quality, reliability and release frequency. Mentor and guide other developers; enforce engineering best practices, code quality, and architectural integrity.\r\nCollaborate with Solutions Architect, DevOps, and Data teams to translate business needs into scalable technical designs.\r\nEnsure all development follows SDLC, validation, GxP, and 21 CFR Part 11 requirements.\r\nDesign secure integrations with external clinical and operational systems.\r\nTroubleshoot complex system issues and lead root cause analysis.\r\nDrive continuous improvement in cloud performance, cost optimization, security posture, and CI/CD automation.\r\nUnderstands and continues to stay current with the AWS Cloud development environment and tools that the systems utilize.\r\nManages time effectively. Accurately estimates effort for tasks and meets agreed-upon deadlines. Adapts to frequently changing requirements, priorities, and schedules.\r\nTroubleshoots and resolves technical issues in a timely manner, performs root cause analyses, and drives permanent fixes and technical debt reduction.\r\nContribute to architecture discussions and technology choices, balancing innovation with maintainability and regulatory constraints.\r\nPromote a culture of documentation, knowledge sharing and continuous learning within the application development team. Provide technical mentorship and oversight through design reviews, pairing programming and structured feedback.\r\nWhat You Need Minimum 8 years of experience as a full stack developer\r\nMinimum 3 years of experience leading a development team focused on building On-prem and Cloud applications Core stack C#/ASP.NET, .NET, Angular, SQL, NO SQL, and AWS\r\nProficient in Angular and experience in a recent project\r\nStrong experience redeveloping on-prem web applications to be optimized for the AWS Cloud. Experience leading a Cloud software development project end to end: architecture, implementation, testing, deployment, and support.\r\nExperience building AWS based web sites, applications and integrations\r\nAWS services such as CloudWatch, SES, S3, ECR, ECS, Lambda functions\r\nUI/UX experience using Blazor or Angular\r\nRelational and non-relational databases\r\nAll aspects of GitHub , including GitHub Actions\r\nExperience with Docker containers\r\nStrong experience with the management of code through a CI/CD pipeline\r\nPreferred Experience Experience configuring AWS environment using Terraform, Fargate, etc.\r\nExperience in a CRO/pharmaceutical environment with definitive knowledge of regulated clinical data applications\r\nKnowledge of GxP and 21 CFR Part 11 compliance\r\nExperience with migrating an entire on-prem data center to the AWS Cloud\r\nWhat We Offer At Theradex we offer a supportive culture that puts people first. Our employees are eligible to participate in our comprehensive benefits package which includes medical, dental and vision coverage; life insurance, disability insurance (STD/LTD), company matched 401(k), very competitive tuition reimbursement, generous vacation/sick plans, flexible work schedules, employee discounts and other company provided benefits. The annual base salary for this position ranges from $140,000 - $175,000. The actual salary offer will be based on a number of factors, including but not limited to the candidate's qualifications, experience, skills, and competencies for the role.\r\nThis position is not eligible for relocation or company provided sponsorship.\r\nEqual employment opportunity, including veterans and individuals with disabilities.\r\nPI283520804\r\nJ-18808-Ljbffr","company":"Theradex Systems","rawCompany":"theradex systems","city":"Princeton","state":"NJ","isRemote":false,"isActive":false,"createdAt":"2026-04-09T08:03:41.823Z","occupations":[{"code":"15-1252.00","title":"Software Developers","slug":"software-developers"},{"code":"15-1254.00","title":"Web Developers","slug":"web-developers"},{"code":"15-1299.08","title":"Computer Systems Engineers/Architects","slug":"computer-systems-engineers-architects"}],"industries":[{"code":"541512","title":"Computer Systems Design Services","slug":"computer-systems-design-services"},{"code":"541511","title":"Custom Computer Programming Services","slug":"custom-computer-programming-services"},{"code":"513210","title":"Software Publishers","slug":"software-publishers"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Lead Full Stack Developer (C#/.NET)","description":"Theradex Systems, Inc.\r\nTheradex is an Equal Opportunity Employer.\r\nUS-NJ-Princeton | US\r\nID 2026-1426\r\nCategory Information Technology\r\nType Full Time\r\nWho We Are Celebrating 40+ years!\r\nTheradex Oncology is a full-service CRO specializing in oncology. The company manages global oncology trials and programs. The company was founded in 1982 working with the National Cancer Institute, which led to its expansion to working with industry sponsors developing cancer therapeutics. As a service-based company we support both domestic and international sponsors in the conduct of both early and late phase trials.\r\nWhat You'll Do Location: Princeton, NJ (Hybrid – Onsite 3 days/week preferred) - Will consider regionally remote candidates.\r\nAs part of Theradex Oncology, you will have the opportunity to work with one of the largest professional teams focused solely on the development of cancer therapies. Cancer research continues to evolve as new therapies and therapeutic approaches are discovered, as part of the team you will work to support our sponsors in the development of these therapies. Theradex Oncology is an environment for highly motivated individuals who want to make a difference.\r\nAbout the Role We are seeking a Lead Full stack developer responsible for designing, building and operating end-to-end web applications and data driven solutions that support clinical trial operations. This is a hands-on technical leadership role, combining senior individual contributor responsibilities with mentoring and guiding other developers on modern practices. This role requires recent hands-on experience owning technical solutions and driving projects forward while maintaining Full Stack Development responsibilities.\r\nKey Responsibilities Oversees application development team's technical delivery across all projects while remaining a hands-on Full Stack Developer.\r\nDesign and implement scalable, secure frontend and backend components, including APIs, services and UI workflows, following clean architecture and solid principles.\r\nEmbed application security best practices into the software development lifecycle, including securing code, code scanning, dependency management, and remediation of vulnerability identified through AppSec tools.\r\nCollaborate with product owners, technical analysts, project managers, platform engineering and analytics teams to translate complex business needs into practical technical solutions.\r\nOwn technical solutions end to end: architecture, implementation, testing, deployment, and support.\r\nEstablish and champion coding standards, automated testing, and CI/CD pipelines to improve quality, reliability and release frequency. Mentor and guide other developers; enforce engineering best practices, code quality, and architectural integrity.\r\nCollaborate with Solutions Architect, DevOps, and Data teams to translate business needs into scalable technical designs.\r\nEnsure all development follows SDLC, validation, GxP, and 21 CFR Part 11 requirements.\r\nDesign secure integrations with external clinical and operational systems.\r\nTroubleshoot complex system issues and lead root cause analysis.\r\nDrive continuous improvement in cloud performance, cost optimization, security posture, and CI/CD automation.\r\nUnderstands and continues to stay current with the AWS Cloud development environment and tools that the systems utilize.\r\nManages time effectively. Accurately estimates effort for tasks and meets agreed-upon deadlines. Adapts to frequently changing requirements, priorities, and schedules.\r\nTroubleshoots and resolves technical issues in a timely manner, performs root cause analyses, and drives permanent fixes and technical debt reduction.\r\nContribute to architecture discussions and technology choices, balancing innovation with maintainability and regulatory constraints.\r\nPromote a culture of documentation, knowledge sharing and continuous learning within the application development team. Provide technical mentorship and oversight through design reviews, pairing programming and structured feedback.\r\nWhat You Need Minimum 8 years of experience as a full stack developer\r\nMinimum 3 years of experience leading a development team focused on building On-prem and Cloud applications Core stack C#/ASP.NET, .NET, Angular, SQL, NO SQL, and AWS\r\nProficient in Angular and experience in a recent project\r\nStrong experience redeveloping on-prem web applications to be optimized for the AWS Cloud. Experience leading a Cloud software development project end to end: architecture, implementation, testing, deployment, and support.\r\nExperience building AWS based web sites, applications and integrations\r\nAWS services such as CloudWatch, SES, S3, ECR, ECS, Lambda functions\r\nUI/UX experience using Blazor or Angular\r\nRelational and non-relational databases\r\nAll aspects of GitHub , including GitHub Actions\r\nExperience with Docker containers\r\nStrong experience with the management of code through a CI/CD pipeline\r\nPreferred Experience Experience configuring AWS environment using Terraform, Fargate, etc.\r\nExperience in a CRO/pharmaceutical environment with definitive knowledge of regulated clinical data applications\r\nKnowledge of GxP and 21 CFR Part 11 compliance\r\nExperience with migrating an entire on-prem data center to the AWS Cloud\r\nWhat We Offer At Theradex we offer a supportive culture that puts people first. Our employees are eligible to participate in our comprehensive benefits package which includes medical, dental and vision coverage; life insurance, disability insurance (STD/LTD), company matched 401(k), very competitive tuition reimbursement, generous vacation/sick plans, flexible work schedules, employee discounts and other company provided benefits. The annual base salary for this position ranges from $140,000 - $175,000. The actual salary offer will be based on a number of factors, including but not limited to the candidate's qualifications, experience, skills, and competencies for the role.\r\nThis position is not eligible for relocation or company provided sponsorship.\r\nEqual employment opportunity, including veterans and individuals with disabilities.\r\nPI283520804\r\nJ-18808-Ljbffr","datePosted":"2026-04-09T08:03:41.823Z","dateModified":"2026-04-09T08:03:41.823Z","hiringOrganization":{"@type":"Organization","name":"Theradex Systems","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Princeton","addressRegion":"NJ","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"455b2284dc7709db489f4671"},"url":"https://jobsearcher.com/jobs/455b2284dc7709db489f4671"}}