Principal Clinical Scientist

Principal Clinical Scientist (AI Training)About The RoleWhat if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about clinical evidence?We're looking for a Principal Clinical Scientist to bring senior-level rigor to one of the most consequential frontiers in modern technology: AI systems trained on clinical and biomedical data. Your expertise will help ensure that the AI models influencing the future of healthcare research are grounded in the same scientific standards expected by the FDA, EMA, and their global counterparts.This is a fully remote, flexible contract role built for experienced clinical scientists who want to contribute to something genuinely new — without leaving behind the discipline and precision that defines their work.Organization: AlignerrType: Hourly ContractLocation: RemoteCommitment: 10–40 hours/weekWhat You'll DoDesign and review clinical trial protocols used to generate high-quality, regulator-ready training datasets for AI systemsInterpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standardsEvaluate AI-generated clinical analyses for scientific soundness and regulatory relevanceProvide expert, structured feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomesHelp establish the bar for what good clinical reasoning looks like — at the frontier of AI developmentWho You AreSenior clinical scientist with hands-on experience designing clinical trial protocols for regulatory submissionDeep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent global bodiesStrong foundation in clinical research methodology, biostatistics, translational science, or a closely related disciplineNaturally rigorous — you hold AI-generated outputs to the same standards you'd apply in a real submission contextComfortable working independently in an asynchronous, remote environmentNice to HavePrior experience with data annotation, data quality evaluation, or AI output assessmentBackground in drug development, medical devices, or diagnosticsFamiliarity with clinical data standards such as CDISC, ICH guidelines, or GCP frameworksWhy Join UsWork directly on frontier AI systems with real impact on clinical and biomedical researchFully remote and asynchronous — work on your schedule, from anywhereFreelance autonomy combined with meaningful, substantive workInfluence how AI understands, evaluates, and communicates real-world clinical evidenceCollaborate with leading AI research teams and labs at the cutting edge of the fieldPotential for ongoing work and contract extension as projects evolve