{"schemaVersion":"jobsearcher.job.v1","id":"2a2ac9d43970f67b3a3f2c63","url":"https://jobsearcher.com/jobs/2a2ac9d43970f67b3a3f2c63","canonicalUrl":"https://jobsearcher.com/jobs/2a2ac9d43970f67b3a3f2c63","title":"Principal, Quantitative Sciences","description":"At Target RWE, our mission is driven by a deep commitment to people, whether it's the patients we serve, the partners we collaborate with, or the dedicated team members who power our work. As a purpose-driven organization, we leverage real-world data to advance clinical research and inform better healthcare decisions. We foster a collaborative environment where every voice is heard, every idea has an impact, and every contribution helps improve lives. If you're seeking a place where your work truly matters, join us to advance science.\nOverview\nWe are seeking a Principal to join Target RWE's Quantitative Sciences (QS) organization. In this role, you will help shape how we design, execute, and communicate real-world clinical studies using Target's data.\nThis is a highly cross-functional and client-facing role. You will bring strong analytical and scientific expertise, paired with the ability to apply the right level of methodological rigor for the question at hand, balancing credibility, practicality, and clarity. You will work closely with internal teams and external partners to ensure analyses are scientifically sound, clearly communicated, and aligned with real-world use cases.\nYou will serve as a key representative of Target's scientific capabilities, engaging directly with pharmaceutical and biotech partners, supporting client discussions, and helping translate complex analytical approaches into clear, actionable insights.\nWhat You'll Do\nApplied Methodology and Study Design\nYou will ensure that Target's analyses are scientifically rigorous, practical, and aligned with real-world use.\nGuide the design of observational studies using real-world data, including retrospective and prospective analyses\nApply statistical and epidemiologic methods in a practical, fit-for-purpose way\nDevelop and review study protocols and statistical analysis plans\nEnsure analyses are reproducible, interpretable, and aligned with regulatory and scientific expectations\nPartner with internal teams to translate research questions into practical analytic approaches\nClient-Facing Scientific Leadership\nYou will serve as a key scientific voice in client and partner interactions.\nParticipate in and lead client meetings to explain study design, methodology, and results\nTranslate complex analytical concepts into clear, accessible language for diverse audiences\nSupport business development efforts by helping communicate Target's scientific approach and data value\nRepresent Target in external settings, including conferences, scientific collaborations, and partner discussions\nBuild trust with clients by providing thoughtful, pragmatic, and credible scientific guidance\nCross-Functional Collaboration\nYou will connect data, analytics, and business needs across the organization.\nPartner closely with Product, Engineering, Medical Science, Clinical Operations, and Commercial teams\nHelp shape analytic strategies that align with both scientific goals and customer needs\nProvide guidance to the Quantitative Sciences team on study design and interpretation\nMentor team members on balancing methodological rigor with practical execution\nContribute to internal best practices for scalable, high-quality evidence generation\nWhat You'll Bring\nPhD or MS in biostatistics, epidemiology, health economics, data science, or a related field\n10+ years of experience working with real-world data (EMR, claims, registry, or clinical trial data)\nStrong foundation in observational study design and applied statistical methods; experience with real-world pragmatic clinical trial designs is a plus\nDemonstrated ability to apply methods pragmatically, selecting the right approach for the problem\nWillingness to engage directly with data and analyses as needed, with working knowledge of R and/or SQL to support exploratory work, validation, and collaboration with analytic teams\nExperience working directly with clients or external partners in life sciences or healthcare\nExcellent communication and presentation skills, with the ability to explain complex concepts clearly\nComfortable operating in client-facing settings, including meetings, presentations, and scientific discussions\nStrong collaboration skills across technical and non-technical teams\nWhat we offer you\nHybrid work — 3 days/week in our brand-new office!\nComprehensive health, dental, and vision for you and your family\n401(k) with company match\nGenerous PTO and company holidays\nPaid parental leave\nHybrid role: Located in Research Triangle Park, North Carolina","company":"Targetrwe","rawCompany":"targetrwe","city":"Durham","state":"NC","isRemote":false,"isActive":false,"createdAt":"2026-07-16T17:58:51.653Z","occupations":[{"code":"11-9121.00","title":"Natural Sciences Managers","slug":"natural-sciences-managers"},{"code":"15-2041.00","title":"Statisticians","slug":"statisticians"},{"code":"19-1042.00","title":"Medical Scientists, Except Epidemiologists","slug":"medical-scientists-except-epidemiologists"}],"industries":[{"code":"541690","title":"Other Scientific and Technical Consulting Services","slug":"other-scientific-and-technical-consulting-services"},{"code":"541715","title":"Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)","slug":"research-and-development-in-the-physical-engineering-and-life-sciences-except-nanotechnology-and-biotechnology"},{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Principal, Quantitative Sciences","description":"At Target RWE, our mission is driven by a deep commitment to people, whether it's the patients we serve, the partners we collaborate with, or the dedicated team members who power our work. As a purpose-driven organization, we leverage real-world data to advance clinical research and inform better healthcare decisions. We foster a collaborative environment where every voice is heard, every idea has an impact, and every contribution helps improve lives. If you're seeking a place where your work truly matters, join us to advance science.\nOverview\nWe are seeking a Principal to join Target RWE's Quantitative Sciences (QS) organization. In this role, you will help shape how we design, execute, and communicate real-world clinical studies using Target's data.\nThis is a highly cross-functional and client-facing role. You will bring strong analytical and scientific expertise, paired with the ability to apply the right level of methodological rigor for the question at hand, balancing credibility, practicality, and clarity. You will work closely with internal teams and external partners to ensure analyses are scientifically sound, clearly communicated, and aligned with real-world use cases.\nYou will serve as a key representative of Target's scientific capabilities, engaging directly with pharmaceutical and biotech partners, supporting client discussions, and helping translate complex analytical approaches into clear, actionable insights.\nWhat You'll Do\nApplied Methodology and Study Design\nYou will ensure that Target's analyses are scientifically rigorous, practical, and aligned with real-world use.\nGuide the design of observational studies using real-world data, including retrospective and prospective analyses\nApply statistical and epidemiologic methods in a practical, fit-for-purpose way\nDevelop and review study protocols and statistical analysis plans\nEnsure analyses are reproducible, interpretable, and aligned with regulatory and scientific expectations\nPartner with internal teams to translate research questions into practical analytic approaches\nClient-Facing Scientific Leadership\nYou will serve as a key scientific voice in client and partner interactions.\nParticipate in and lead client meetings to explain study design, methodology, and results\nTranslate complex analytical concepts into clear, accessible language for diverse audiences\nSupport business development efforts by helping communicate Target's scientific approach and data value\nRepresent Target in external settings, including conferences, scientific collaborations, and partner discussions\nBuild trust with clients by providing thoughtful, pragmatic, and credible scientific guidance\nCross-Functional Collaboration\nYou will connect data, analytics, and business needs across the organization.\nPartner closely with Product, Engineering, Medical Science, Clinical Operations, and Commercial teams\nHelp shape analytic strategies that align with both scientific goals and customer needs\nProvide guidance to the Quantitative Sciences team on study design and interpretation\nMentor team members on balancing methodological rigor with practical execution\nContribute to internal best practices for scalable, high-quality evidence generation\nWhat You'll Bring\nPhD or MS in biostatistics, epidemiology, health economics, data science, or a related field\n10+ years of experience working with real-world data (EMR, claims, registry, or clinical trial data)\nStrong foundation in observational study design and applied statistical methods; experience with real-world pragmatic clinical trial designs is a plus\nDemonstrated ability to apply methods pragmatically, selecting the right approach for the problem\nWillingness to engage directly with data and analyses as needed, with working knowledge of R and/or SQL to support exploratory work, validation, and collaboration with analytic teams\nExperience working directly with clients or external partners in life sciences or healthcare\nExcellent communication and presentation skills, with the ability to explain complex concepts clearly\nComfortable operating in client-facing settings, including meetings, presentations, and scientific discussions\nStrong collaboration skills across technical and non-technical teams\nWhat we offer you\nHybrid work — 3 days/week in our brand-new office!\nComprehensive health, dental, and vision for you and your family\n401(k) with company match\nGenerous PTO and company holidays\nPaid parental leave\nHybrid role: Located in Research Triangle Park, North Carolina","datePosted":"2026-07-16T17:58:51.653Z","dateModified":"2026-07-16T17:58:51.653Z","hiringOrganization":{"@type":"Organization","name":"Targetrwe","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Durham","addressRegion":"NC","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"2a2ac9d43970f67b3a3f2c63"},"url":"https://jobsearcher.com/jobs/2a2ac9d43970f67b3a3f2c63"}}