{"schemaVersion":"jobsearcher.job.v1","id":"23ff5a45b33b52e9c9c22f62","url":"https://jobsearcher.com/jobs/23ff5a45b33b52e9c9c22f62","canonicalUrl":"https://jobsearcher.com/jobs/23ff5a45b33b52e9c9c22f62","title":"Principal Software Engineer","description":"About eClinical Solutions\neClinical Solutions is transforming clinical development with elluminate®, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle—accelerating innovation that ultimately improves patient outcomes.\nOur engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you're excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.\n\nYou will make an impact:\nAs a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team. You'll help design and build the core services and user experiences of a next-generation clinical data and analytics platform—while influencing architecture, engineering standards, and technical direction.\nThis role is ideal for an experienced engineer who enjoys hands-on development, mentoring others, and bringing modern capabilities—including AI-assisted and agentic workflows—into production-grade systems.\n\nYour day to day:\nDesign, develop, test, and deploy scalable, secure, and highly interactive web applications\nOwn and evolve core platform modules, from concept through release and support\nInfluence application and system architecture with a focus on performance, reliability, security, and maintainability\nLead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions\nCollaborate closely with Product Management, QA, and other engineers throughout the SDLC\nProvide technical mentorship and guidance to other engineers on the team\nDiagnoses and resolves complex production issues across distributed systems\nEnsure solutions meet eClinical Solutions quality standards and applicable industry regulations\nContribute to technical documentation including design specs, acceptance criteria, and release notes\nAI & Modern Engineering Focus\nWe're actively incorporating AI-powered capabilities into our platform, and you'll help shape how this is done responsibly and effectively in an enterprise environment. This includes:\nIntegrating LLMs and AI services into .NET- and Python-based systems\nDesigning and implementing AI-assisted workflows, copilots, or intelligent automation features\nWorking with agentic AI patterns (e.g., task orchestration, tool-using agents, workflow automation)\nApplying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance\nCollaborating with data and platform teams to operationalize AI—not just prototype it\nDeep ML expertise is not required—we're looking for strong engineers who understand how to apply AI capabilities in real products.\nTake the first step toward your dream career. Here is what we are looking for in this role.\nQualifications:\nBachelor's or Master's degree in Computer Science or equivalent practical experience\n10+ years in software design and development using the Microsoft technology stack preferred\nExpert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs)\nStrong experience building full-stack web applications (Angular, TypeScript, HTML, CSS)\nSolid understanding of software design principles, patterns, and best practices\nExperience across the full Software Development Lifecycle (Agile preferred)\nProven ability to work independently while collaborating effectively in a fast-paced environment\nExcellent communication, documentation, and technical leadership skills\nAI & Platform Experience\nHands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications\nExperience using Python and/or .NET alongside AI/LLM workflows\nFamiliarity with agent-based or workflow-driven AI architectures is a strong plus\nUnderstanding of secure and responsible AI usage in enterprise systems\nNice to Have\nStrong SQL expertise (Microsoft SQL Server preferred), including performance tuning\nExperience with microservices, distributed systems, and cloud platforms (AWS preferred)\nSecure development experience, including awareness of common vulnerabilities and mitigations\nExperience with clinical trial data, life sciences, or regulated SaaS environments\nExperience building data visualizations or analytics-driven user experiences\nAccelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!\neClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: https://topworkplaces.com/company/eclinical-solutions/\neClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here!\nWe are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.\n\n#LI-AB1","company":"Eclinical Solutions","rawCompany":"eclinical solutions","city":"Marshfield","state":"MA","isRemote":false,"isActive":false,"createdAt":"2026-08-11T16:08:45.487Z","occupations":[{"code":"15-1252.00","title":"Software Developers","slug":"software-developers"},{"code":"15-1299.08","title":"Computer Systems Engineers/Architects","slug":"computer-systems-engineers-architects"},{"code":"15-1211.00","title":"Computer Systems Analysts","slug":"computer-systems-analysts"}],"industries":[{"code":"513210","title":"Software Publishers","slug":"software-publishers"},{"code":"541511","title":"Custom Computer Programming Services","slug":"custom-computer-programming-services"},{"code":"541512","title":"Computer Systems Design Services","slug":"computer-systems-design-services"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Principal Software Engineer","description":"About eClinical Solutions\neClinical Solutions is transforming clinical development with elluminate®, our Clinical Data Cloud, helping life sciences organizations unify, analyze, and unlock the value of their data faster than ever before. By combining a modern cloud platform with expert data services, we empower smarter decisions across the clinical trial lifecycle—accelerating innovation that ultimately improves patient outcomes.\nOur engineering teams build enterprise-grade, revenue-generating products at the intersection of cloud, data, analytics, and emerging AI technologies. If you're excited about building sophisticated software that makes a real-world impact on healthcare, this is the place to do it.\n\nYou will make an impact:\nAs a Principal Full Stack Software Engineer, you will be a technical leader within the elluminate Product Development team. You'll help design and build the core services and user experiences of a next-generation clinical data and analytics platform—while influencing architecture, engineering standards, and technical direction.\nThis role is ideal for an experienced engineer who enjoys hands-on development, mentoring others, and bringing modern capabilities—including AI-assisted and agentic workflows—into production-grade systems.\n\nYour day to day:\nDesign, develop, test, and deploy scalable, secure, and highly interactive web applications\nOwn and evolve core platform modules, from concept through release and support\nInfluence application and system architecture with a focus on performance, reliability, security, and maintainability\nLead by example through clean, well-tested code, thoughtful design reviews, and pragmatic technical decisions\nCollaborate closely with Product Management, QA, and other engineers throughout the SDLC\nProvide technical mentorship and guidance to other engineers on the team\nDiagnoses and resolves complex production issues across distributed systems\nEnsure solutions meet eClinical Solutions quality standards and applicable industry regulations\nContribute to technical documentation including design specs, acceptance criteria, and release notes\nAI & Modern Engineering Focus\nWe're actively incorporating AI-powered capabilities into our platform, and you'll help shape how this is done responsibly and effectively in an enterprise environment. This includes:\nIntegrating LLMs and AI services into .NET- and Python-based systems\nDesigning and implementing AI-assisted workflows, copilots, or intelligent automation features\nWorking with agentic AI patterns (e.g., task orchestration, tool-using agents, workflow automation)\nApplying prompt engineering, evaluation techniques, and guardrails to ensure reliability and compliance\nCollaborating with data and platform teams to operationalize AI—not just prototype it\nDeep ML expertise is not required—we're looking for strong engineers who understand how to apply AI capabilities in real products.\nTake the first step toward your dream career. Here is what we are looking for in this role.\nQualifications:\nBachelor's or Master's degree in Computer Science or equivalent practical experience\n10+ years in software design and development using the Microsoft technology stack preferred\nExpert-level proficiency in C#, .NET, and ASP.NET (MVC/Web APIs)\nStrong experience building full-stack web applications (Angular, TypeScript, HTML, CSS)\nSolid understanding of software design principles, patterns, and best practices\nExperience across the full Software Development Lifecycle (Agile preferred)\nProven ability to work independently while collaborating effectively in a fast-paced environment\nExcellent communication, documentation, and technical leadership skills\nAI & Platform Experience\nHands-on experience integrating LLM-based services (e.g., OpenAI, Azure OpenAI, or similar) into applications\nExperience using Python and/or .NET alongside AI/LLM workflows\nFamiliarity with agent-based or workflow-driven AI architectures is a strong plus\nUnderstanding of secure and responsible AI usage in enterprise systems\nNice to Have\nStrong SQL expertise (Microsoft SQL Server preferred), including performance tuning\nExperience with microservices, distributed systems, and cloud platforms (AWS preferred)\nSecure development experience, including awareness of common vulnerabilities and mitigations\nExperience with clinical trial data, life sciences, or regulated SaaS environments\nExperience building data visualizations or analytics-driven user experiences\nAccelerate your skills and career within a fast-growing company while impacting the future of healthcare. We have shared our story, now we look forward to learning yours!\neClinical is a winner of the 2025 Top Workplaces USA Award for Remote Work! We have also received numerous Top Workplaces Culture Excellence Awards celebrating our exceptional company vision, values, and work-life balance. See all the details here: https://topworkplaces.com/company/eclinical-solutions/\neClinical Solutions is a people first organization. Our inclusive culture values the contribution that diversity brings to our business. We celebrate individual experiences that connect us and that inspire innovation in our community. Our team seeks out opportunities to learn, grow and continuously improve. Bring your authentic self, you are welcome here!\nWe are proud to be an equal opportunity employer that values diversity. Our management team is committed to the principle that employment decisions are based on qualifications, merit, culture fit and business need.\n\n#LI-AB1","datePosted":"2026-08-11T16:08:45.487Z","dateModified":"2026-08-11T16:08:45.487Z","hiringOrganization":{"@type":"Organization","name":"Eclinical Solutions","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Marshfield","addressRegion":"MA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"23ff5a45b33b52e9c9c22f62"},"url":"https://jobsearcher.com/jobs/23ff5a45b33b52e9c9c22f62"}}