{"schemaVersion":"jobsearcher.job.v1","id":"0a82c1f7affb26b0e333607c","url":"https://jobsearcher.com/jobs/0a82c1f7affb26b0e333607c","canonicalUrl":"https://jobsearcher.com/jobs/0a82c1f7affb26b0e333607c","title":"Process Engineer, Formulation Development","description":"At Editas Medicine, we are pioneering the possible. Our mission and commitment is to translate the power and potential of the CRISPR/Cas12a and CRISPR/Cas9 genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for a broad class of diseases.\nWhy Choose Editas?\nAt Editas Medicine, we’re a team of courageous problem solvers, harnessing the power and potential of CRISPR gene editing to transform the future of medicine. Driven by a shared purpose to serve people living with serious diseases, we succeed together through collaboration, mutual respect, and innovation. If you want to be part of a team where your voice is heard and respected, where you can operate at the forefront of gene editing, and push the boundaries of what’s possible in medicine, come join us and become an Editor!\nDecoding The Role:\nAs a Process Engineer, you’ll be a vital contributor to our mission and our success. The in vivo Gene Editing and Critical Components Process Development team in the Technical Development Department is seeking a highly motivated Process Engineer for the process and formulation development of critical gene editing components and drug products [e.g. Ribonucleoprotein (RNP), messenger RNA (mRNA) & Lipid Nanoparticle (LNP)]. The successful candidate will support the design and execution of pertinent process and formulation development projects, coordinating with process and analytical experts within Technical Development and cross-functionally in Research and Discovery, Technical Operations, Manufacturing, and Quality, to advance Editas’ ex vivo and in vivo gene editing programs.\nCharacterizing Your Impact:\nAs the Process Engineer, you will:\nLead or support experiments for RNP, mRNA/LNP manufacturing process definition, scale-down model qualification, process characterization/optimization and scale-up to meet clinical and commercial material demand\nSupport the generation of representative materials for analytical method development and toxicology studies\nSupport technology transfer of mRNA/LNP manufacturing process to internal or external manufacturing facilities for clinical and commercial manufacturing, in collaboration with Manufacturing and Quality teams\nCollaborate with AD to generate data for formulation studies, stability studies, and characterization of drug substance and/or drug product\nProvide technical support for engineering and cGMP manufacturing campaigns (e.g. batch record review, change control management, deviation investigation, etc) in collaboration with other line functions (e.g., Manufacturing Sciences & Technology), as needed\nDocument all experimental work, supporting information, and data in an electronic lab notebook (eLN) in a timely manner\nCompile and present data, and assist in authoring and reviewing of batch records, work instructions, protocols, plans, technical reports, SOPs, and may contribute to regulatory document drafting and review\nCross-train personnel on processes, and provide guidance to junior team members, as required\nMaintain abreast latest industry trends for RNP, LNP and nucleic acid-based process and product knowledge\nContribute to equipment procurement, setup and training\nOther responsibilities as required.\nRequirements\nThe Ideal Transcript:\nTo thrive in this role, you’ll need:\nBachelor’s experience in Chemical Engineering, Biomedical Engineering, Chemistry, Pharmaceutical Sciences, or related discipline with 6+ years of relevant experience or Master’s with 4+ years of experience.\nStrong technical expertise and meaningful hands-on experience in mRNA/LNP formulation development, scale-up and/or manufacturing in a drug development setting are required.\nProficient UFDF/Dialysis operation skills with solid understanding of scale-up principles.\nProficient verbal communication and technical writing skills.\nFundamentals That Set You Apart\nSolid knowledge and experience with QbD and common risk assessment tools for process development and characterization are highly preferred.\nWorking knowledge of general downstream purification techniques (e.g. depth filtration, Chromatography) is a plus.\nExperience in molecular biology and microbial manufacturing of nucleic acids or protein are preferred.\nExperience in Technical Transfer of cGMP manufacturing processes and regulatory filing support for biologics.\nWorking knowledge of mRNA, LNP and pertinent raw material (e.g. lipids) characterization methods and specifications is highly preferred.\nStrong organizational skills with the ability to multi-task, problem-solve, and adjust priorities to meet goals in a fast-paced environment.\nBenefits\nBenefits Summary:\nEditas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.\nAspire to be an Editor? We invite you to apply and join us at the forefront of innovation and be a key contributor to realizing Editas Medicine's mission of developing transformative medicines for people living with serious diseases.","company":"Editas Medicine","rawCompany":"editas medicine","city":"Somerville","state":"MA","isRemote":false,"isActive":false,"createdAt":"2026-04-12T20:32:15.905Z","occupations":[{"code":"17-2041.00","title":"Chemical Engineers","slug":"chemical-engineers"},{"code":"17-2112.02","title":"Validation Engineers","slug":"validation-engineers"},{"code":"17-2199.00","title":"Engineers, All Other","slug":"engineers-all-other"}],"industries":[{"code":"541714","title":"Research and Development in Biotechnology (except Nanobiotechnology)","slug":"research-and-development-in-biotechnology-except-nanobiotechnology"},{"code":"325414","title":"Biological Product (except Diagnostic) Manufacturing","slug":"biological-product-except-diagnostic-manufacturing"},{"code":"325412","title":"Pharmaceutical Preparation Manufacturing","slug":"pharmaceutical-preparation-manufacturing"}],"jobPosting":{"@context":"https://schema.org","@type":"JobPosting","title":"Process Engineer, Formulation Development","description":"At Editas Medicine, we are pioneering the possible. Our mission and commitment is to translate the power and potential of the CRISPR/Cas12a and CRISPR/Cas9 genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for a broad class of diseases.\nWhy Choose Editas?\nAt Editas Medicine, we’re a team of courageous problem solvers, harnessing the power and potential of CRISPR gene editing to transform the future of medicine. Driven by a shared purpose to serve people living with serious diseases, we succeed together through collaboration, mutual respect, and innovation. If you want to be part of a team where your voice is heard and respected, where you can operate at the forefront of gene editing, and push the boundaries of what’s possible in medicine, come join us and become an Editor!\nDecoding The Role:\nAs a Process Engineer, you’ll be a vital contributor to our mission and our success. The in vivo Gene Editing and Critical Components Process Development team in the Technical Development Department is seeking a highly motivated Process Engineer for the process and formulation development of critical gene editing components and drug products [e.g. Ribonucleoprotein (RNP), messenger RNA (mRNA) & Lipid Nanoparticle (LNP)]. The successful candidate will support the design and execution of pertinent process and formulation development projects, coordinating with process and analytical experts within Technical Development and cross-functionally in Research and Discovery, Technical Operations, Manufacturing, and Quality, to advance Editas’ ex vivo and in vivo gene editing programs.\nCharacterizing Your Impact:\nAs the Process Engineer, you will:\nLead or support experiments for RNP, mRNA/LNP manufacturing process definition, scale-down model qualification, process characterization/optimization and scale-up to meet clinical and commercial material demand\nSupport the generation of representative materials for analytical method development and toxicology studies\nSupport technology transfer of mRNA/LNP manufacturing process to internal or external manufacturing facilities for clinical and commercial manufacturing, in collaboration with Manufacturing and Quality teams\nCollaborate with AD to generate data for formulation studies, stability studies, and characterization of drug substance and/or drug product\nProvide technical support for engineering and cGMP manufacturing campaigns (e.g. batch record review, change control management, deviation investigation, etc) in collaboration with other line functions (e.g., Manufacturing Sciences & Technology), as needed\nDocument all experimental work, supporting information, and data in an electronic lab notebook (eLN) in a timely manner\nCompile and present data, and assist in authoring and reviewing of batch records, work instructions, protocols, plans, technical reports, SOPs, and may contribute to regulatory document drafting and review\nCross-train personnel on processes, and provide guidance to junior team members, as required\nMaintain abreast latest industry trends for RNP, LNP and nucleic acid-based process and product knowledge\nContribute to equipment procurement, setup and training\nOther responsibilities as required.\nRequirements\nThe Ideal Transcript:\nTo thrive in this role, you’ll need:\nBachelor’s experience in Chemical Engineering, Biomedical Engineering, Chemistry, Pharmaceutical Sciences, or related discipline with 6+ years of relevant experience or Master’s with 4+ years of experience.\nStrong technical expertise and meaningful hands-on experience in mRNA/LNP formulation development, scale-up and/or manufacturing in a drug development setting are required.\nProficient UFDF/Dialysis operation skills with solid understanding of scale-up principles.\nProficient verbal communication and technical writing skills.\nFundamentals That Set You Apart\nSolid knowledge and experience with QbD and common risk assessment tools for process development and characterization are highly preferred.\nWorking knowledge of general downstream purification techniques (e.g. depth filtration, Chromatography) is a plus.\nExperience in molecular biology and microbial manufacturing of nucleic acids or protein are preferred.\nExperience in Technical Transfer of cGMP manufacturing processes and regulatory filing support for biologics.\nWorking knowledge of mRNA, LNP and pertinent raw material (e.g. lipids) characterization methods and specifications is highly preferred.\nStrong organizational skills with the ability to multi-task, problem-solve, and adjust priorities to meet goals in a fast-paced environment.\nBenefits\nBenefits Summary:\nEditas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.\nAspire to be an Editor? We invite you to apply and join us at the forefront of innovation and be a key contributor to realizing Editas Medicine's mission of developing transformative medicines for people living with serious diseases.","datePosted":"2026-04-12T20:32:15.905Z","dateModified":"2026-04-12T20:32:15.905Z","hiringOrganization":{"@type":"Organization","name":"Editas Medicine","sameAs":"https://jobsearcher.com"},"jobLocation":{"@type":"Place","address":{"@type":"PostalAddress","addressLocality":"Somerville","addressRegion":"MA","addressCountry":"US"}},"identifier":{"@type":"PropertyValue","name":"JobSearcher","value":"0a82c1f7affb26b0e333607c"},"url":"https://jobsearcher.com/jobs/0a82c1f7affb26b0e333607c"}}