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Pursuing M.S./PhD in protein engineering, biochemistry, molecular biology, biomedical engineering, or a related field. Experience with protein characterization and protein purification such as SDS-PAGE, IMAC and/or ion exchange purification.
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Our group supports 5000 different protein products used in academic research, pharmaceutical research, and all facets of biological science including: neurodegenerative diseases, stem cell research, glycobiology, developmental biology, etc.
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Summary: Vaxcyte is looking for a highly skilled, motivated, and talented analytical scientist to join Vaxcyte’s Vaccine Product Development organization as Senior Associate Scientist within Protein Development and Clinical Manufacturing.
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We are looking for a computational biologist, structural biologist, biochemist or chemist, biological engineer, or Ph. D.s in related fields with an interest in designing protein structures to tackle challenging problems.
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Is involved in interdisciplinary research, combining protein engineering, immunology, and molecular biology. Performs wet lab work including bacteria culture, mammalian cell culture, protein production, and biomolecular assays in addition to animal (mouse) handling including injections and tumor measurements.
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The successful candidate will be a valuable member of a growing energetic team of cell scientists, whose responsibilities include stable cell line production, generation of cell biomass and assay ready cells, supporting drug development efforts at different levels and recombinant protein expression in mammalian cells.
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A strong background in protein chemistry will be essential to perform and troubleshoot techniques such as HPLC, SDS-PAGE, cell-based bioassays, capillary electrophoresis, SDS-PAGE, ELISA, and standard compendial assays.
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Characterize recombinant antibodies/proteins using SDS-PAGE, protein quantitation, HPLC, ELISA and other biochemical assays to determine protein purity and function. Bachelor's or Master's degree in Biochemistry, Chemistry, or a related field with a minimum of 3 years of protein purification experience.
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Hands-on technical experience in the following areas: protein engineering, enzyme mechanism/kinetics, assay development, protein production systems at medium and pilot-scale, and protein expression, purification, and characterization.
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BMS’s internal engine of innovation includes unrivaled industry leading expertise in CMC development of small molecules, protein biotherapeutics, protein degraders, and other therapeutic modalities.
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Experience with protein purification using an AKTA system and protein characterization using HPLC (analytical SEC), SDS-PAGE, and mass spectrometry. The successful candidate will have a strong background in bacterial expression and protein biochemistry, ideally hands-on experience with small molecule drug discovery.
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The Ring Lab is recruiting a Post-Doctoral Research Fellow with expertise in immunology, systems/computational biology, and/or protein engineering. Immunology Systems biology/bioinformatics Single cell transcriptomics/proteogenomics Protein engineering/directed evolution with yeast, phage, or mRNA/ribosome display technology.
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This is an exceptional opportunity to join a newly founded research center that is pushing the boundaries of targeted protein degradation research and accelerating the translation of basic science into clinical solutions.
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Provide assistance in the execution of experiments and analytical procedures including: molecular biology, DNA cloning, cell culture, protein production, ELISA, Biolayer interferometry and HPLC.
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Lead analytical development and quality control for AAV gene therapy, small molecules, antisense oligonucleotides, mRNA and protein therapeutics. Modalities include AAV gene therapy, small molecules, antisense oligonucleotides, mRNA and protein therapeutics.
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protein job Title: research specialist Company: Cibus
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