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Strong experience in developing and/or executing in vivo models, including dosing (PO, IV, IP, SC), blood and tissue collection, necropsy, and other biometric data collection. Hands-on experience with ex vivo analysis employing contemporary cellular, molecular, and immunological techniques such as PCR or NanoString, flow cytometry, and protein analysis by Western/MSD/ELISA etc.
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Job Overview: The in vivo pharmacology group is currently seeking a highly motivated and scientifically rigorous Research Associate or Associate Scientist to execute in vivo studies and ensure proper care of research animals, while also sharing their passion for finding a lasting cure for patients.
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Oversees and demonstrates experience in in-vivo study operations including dosing, sample collection, necropsy and animal husbandry activities. Experience conducting in vivo and in vitro ADME/toxicokinetic studies.
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The unit offers a wide range of services including: comprehensive animal care, transgenic rodent breeding services, veterinary surveillance, diet preparation and individualized animal dietary services, animal monitoring, surgery and necropsy.
$19.8 - $27.3 an hourFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Performs research support techniques for RBL investigators (e.g., necropsy, blood collection, intraperitoneal, subcutaneous, and oral gavage dosing.) Generates and reports data obtained from all in-vivo procedures and provides insight into data.
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Perform preclinical candidate screening of siRNAs leading to lead compound selection via combined in vitro and in vivo assays, working with or supported by cross-disciplinary groups, including chemistry, bioassay, histology, and in vivo pharmacology, and/or CROs.
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Specific projects include in vitro and in vivo studies to determine the chemopreventative/therapeutic activities of various naturally occurring and synthetic compounds, identify the mechanism of action and assess the safety/toxicity of the agents.
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Proficiency with various mouse handling techniques including dosing (IV, PO, subcutaneous, IP), tumor inoculation/measurements, in life and terminal blood collection, and collection and handling of tissues during necropsy and processing for ex vivo analysis.
$38 - $40 an hourExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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This is an onsite laboratory-based role in preclinical formulations R&D for the intracellular delivery of RNA.The successful candidate will create novel nanoparticles comprising nucleic acids, lipids, polymers and peptides, perform physical-chemical characterizations, and conduct in-vivo / in-vitro studies.
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Gain proficiency in or possess proficiency in-vivo technical skills, including dosing (IP/IV/PO/SC/IM/IT/IN), bleeding (submandibular/ submental/retro-orbital/tail vein/cardiac), euthanasia, and necropsy of laboratory mice.
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Under regular close supervision, performs routine in vivo experimental functions in rodents, which may include: in life observations, dose administrations, sample collections, sample analysis, necropsy, and euthanasia procedures.
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The Jackson Laboratory is seeking an In Vivo Technologist to join the Rare Disease Translational Center (RDTC) team in Bar Harbor, Maine! Provide proactive animal care support to alert the In Vivo team of environmental or unexpected/adverse study-related observations directly impacting animal welfare.
$20.15 - $33.74 an hourFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Highly proficient with in vivo methodology (e.g., dosing, sample collection, physiological monitoring, necropsy). The In Vivo Hub Research Associate will broadly support core operations and report to the In Vivo Research Hub Manager.
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The In Vivo Research Hub serves as a central resource team to support the development and implementation of in vivo models and studies. The successful candidate will be a highly motivated, self-driven individual, and have broad technical proficiencies for in vivo technical support.
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Oversee the In Vivo Operations Department, encompassing In Vivo, Necropsy, Formulations, and Animal Care Departments, with responsibility for monitoring the overall conduct and quality of activities performed in support of non-clinical research studies.
$138,000 - $155,000 a yearFull-timeExpandApply NowActive JobUpdated Yesterday
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