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Extensive in vivo skillset is required, including tumor inoculation and measurement (BLI imaging, caliper), animal dosing (i.v., i.p., and s.c.), blood/tissue collection and ex vivo analysis.
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Clinical research in Dr. Hamrah’s laboratory is focused on using live imaging - in vivo confocal microscopy - to better understand molecular and cellular mechanisms in corneal immunology, neuro-immunology and inflammation.
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Our comprehensive approach involves utilizing diverse cell-based assays, in vivo animal models of asthma and lung fibrosis, and translational research in lung immunology. Conducts experiments using animal models and assessing pulmonary mechanics; experimental methodologies relating to cellular immunology, molecular biology, and biochemistry.
$64,500 - $93,600 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Expertise with mouse handling, in vivo rodent models, multi-color flow cytometry, isolation and culture of primary human and mouse cells and cell lines, cell engineering, scRNseq, and/or bioinformatics analysis is also preferred.
$76,773 - $87,171 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Work may involve duties related to routine performance of assay optimization and ruggedization for analysis of a wide variety of in vivo and in vitro studies involving high-consequence pathogens.
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Provide laboratory support for studies, which may include screening of medical countermeasures for efficacy in vitro and in vivo but may extend to disciplines related to virology. + Previous international field research experience in virology, immunology, molecular biology or public health.
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Qualifications Candidates with a recent PhD or MD/PhD in immunology and experience in murine and/or human T-cell immunology, molecular biology, and in vivo modeling are encouraged to apply.
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Doctoral degree in Molecular biology, Biochemistry, Immunology, Molecular Genetics, or related field. AmplifyBio brings decades of experience to accommodate a wide variety of GLP and non-GLP studies in all in vivo models and dose routes.
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Boehringer Ingelheim is seeking an enthusiastic, creative, and highly motivated Postdoctoral Fellow to join the In Vivo Pharmacology Group in Cancer Immunology and Immune Modulation Department at our US headquarters in Ridgefield, CT. The Ridgefield campus, along with our sister sites in Texas and California, includes a thriving community of postdocs and PhD students that connects globally with their peers on our European campuses.
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As a scientist you will be responsible for the design and execution of in vitro display technologies for lead antibody identification/optimization and collaborating to generate stage-gate appropriate in vitro / cellular / in vivo data packages supporting PoC. The candidate will leverage expertise to develop and implement research to gain a mechanistic understanding of the molecular pharmacology of therapeutic molecules.
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Broad knowledge in molecular and cell biology, immunology, especially in the immuno-oncology cell therapy field required. For Sr Scientist: PhD degree in Immunology, Biology, Biological/Chemical Engineering, or related discipline with 3 + years' experience, or MS with 9+ years' experience, or BS with 11+ years' experience.
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Potential areas of focus include but are not limited to inflammation, host-microbe/microbiome interactions, bioinformatics, global health, vaccine science, autoimmunity, neuroinflammation, cancer immunology, innate immunity, immunopathology, and viral immunity.
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A successful candidate will have had experience with preclinical drug discovery including immunoassays, flow cytometry, cell cytotoxicity assays, and ex vivo cell-based assays. PhD in Immunology, Biology, Biochemistry, or related life science field with proven hands-on experience with 5-10 years of industry experience.
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Technical experience in the development and execution of ELISAs, MSD, gene expression analysis, flow-cytometry, in vitro and ex vivo immunology assays, and/or in vivo pharmacodynamics and pharmacokinetic assays is a plus, but candidate can also be trained.
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Specific projects include in vitro and in vivo studies to determine the preventative and therapeutic activities of various naturally occurring and synthetic compounds, identify the mechanism of action and assess the safety/toxicity of the agents.
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