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Overview Axle is seeking a highly ambitious, adaptable, structured, and detail-oriented Flow Cytometry Immunology Scientist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Vaccine Research Center (VRC), Vaccine Production Program (VPP.
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Broad experience in biochemistry, flow cytometry, molecular biology, in vitro and ex-vivo assays are essential. Independent scientists with a strong command of neuroscience-based in vivo and ex-vivo techniques, metabolism, molecular biology and biochemistry to contribute to target discovery, validation and preclinical development for novel therapeutics are encouraged to apply.
$51ExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Expertise in flow cytometry-based assays (multicolor flow cytometry) of in vitro, ex vivo and in vivo murine and human samples. Prepare samples for flow cytometry and run the flow cytometer for immune cell analysis.
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Experience with CAR T cell production and functional assays is required, including but not limited to cytotoxicity, proliferation, multicolor flow cytometry, and cytokine release assays.
$100,000 - $125,000 a yearExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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The position is focused on phenotyping in vivo models (not performing the in vivo models), tissue harvesting/processing, processing peripheral blood monocytes from clinical samples, flow/mass cytometry, and molecular biology (RNA/protein work.
$31,200 - $38,906 a yearFull-timeExpandUpdated 0 days ago - UpvoteDownvoteShare Job
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These assays encompass a spectrum of techniques, ranging from advanced histopathological analyses utilizing immunohistochemistry and immunofluorescence, to intricate autoradiography, flow cytometry, and ELISA procedures.
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Effectively execute experiments evaluating both in vitro and ex vivo immune readouts, using ELISA, flow cytometry, and other related techniques. Extensive expertise in ELISA (or similar assays), flow cytometry and familiarity with basic molecular biology techniques.
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The incumbent will provide knowledge, assistance and training in molecular biology and immunologic techniques and related data analysis methods, perform flow cytometry, microscopic imaging and related assays of immune tissues and cell functions, perform cell culture studies and studies in small animals (rodents), process human blood and tissues and assist in general lab functions.
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Cell imaging, microscopy, multicolor flow cytometry experience a plus. In collaboration with Chemistry, Biology, In Vivo Pharmacology, and platform teams, contribute to the establishment of SAR to rapidly drive the hit-to-lead process.
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Develop and implement functional assays, including IncuCyte, eSight, RTCA, ELISA, MSD, and multicolor flow cytometry. Lead the design, development, and optimization of T-cell candidates using in vitro and in vivo assays.
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Experience with rodent surgery, bioanalytical assays, flow cytometry, immunohistochemistry, microscopy, qPCR, RNAseq, electrophysiology. Design, write protocols, conduct and report on in vitro and in vivo research studies, as well as clinical feasibility studies.
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Exhaustion assays, as well as on multiparameter flow cytometry assays, is expected. vitro human assay systems and the development and execution of in vivo pharmacology strategies.
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Have strong hands-on expertise using rodent models; cell culture, assay development, and/or flow cytometry analysis is a plus. Assist with monitoring and analyses of experimental mice; may include analysis of hematopoietic cells in culture or flow cytometry.
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Broad experience in analytical techniques used to interrogate ex-vivo cell therapies (CART) and LVV, including but not limited to; molecular techniques (ddPCR, qPCR, NGS), flow cytometry, cell-based methods (bioassays, luciferase-based reporter systems, killing assays), imaging techniques.
$170,000 - $205,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Performing a variety of basic immune and cancer cell biology assays, including in vitro proliferation or apoptosis assays, drug sensitivity assays, flow cytometry and western blotting, in vivo xenograft experiments.
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