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Extensive in vivo skillset is required, including tumor inoculation and measurement (BLI imaging, caliper), animal dosing (i.v., i.p., and s.c.), blood/tissue collection and ex vivo analysis.
$80,000 - $105,000 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Doctoral degree in Molecular biology, Biochemistry, Immunology, Molecular Genetics, or related field. The Scientist/Senior Scientist is responsible for developing and qualifying methods for cellular and/or molecular biology analysis platforms.
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Key Responsibilities: Lead preclinical studies that provide scientific rationale for advancement to human trials, including safety, efficacy, and mechanisms of action studies using clinically relevant in vitro and in vivo models.
ExpandApply NowActive JobUpdated 13 days ago - UpvoteDownvoteShare Job
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Experience with characterization of tumor biology of in vivo models including subcutaneous and orthotopic xenografts or genetically engineered models of cancer. Apply knowledge of pharmacology and biomarker development to enable in vivo assessment of chemical matter and establish pharmacokinetic, pharmacodynamic, and efficacy relationships.
ExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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A successful candidate will have had experience with preclinical drug discovery including immunoassays, flow cytometry, cell cytotoxicity assays, and ex vivo cell-based assays. PhD in Immunology, Biology, Biochemistry, or related life science field with proven hands-on experience with 5-10 years of industry experience.
ExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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The candidate will execute in vivo, small animal medical imaging studies and related in vivo pharmacology procedures, including nuclear medicine (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI.
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Functional validation of results using standard molecular biology techniques will be performed in vitro and in vivo using patient derived xenograft line, primary samples and murine models.
$55,128 - $60,000 a yearFull-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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Qualifications Candidates with a recent PhD or MD/PhD in immunology and experience in murine and/or human T-cell immunology, molecular biology, and in vivo modeling are encouraged to apply.
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A Master's degree with 4-6 years of experience or Bachelor's degree with 6-10 years of equivalent experience in assay development, bacteriology, cell biology, and in-vivo work. Experience in molecular biology (e.g. bacteria mutagenesis, DNA manipulation and cloning, sequence analysis, plasmid vector design and construction) would be a plus.
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Proficiency in advanced genomics approaches (NGS pipelines, single-cell methodologies) and cell/molecular biology techniques (nucleic acid extraction, cell and nuclear dissociation, RT-qPCR). The successful candidate will join a fast-paced, highly productive, and innovative NGS Core team responsible for the expansion, refinement, and execution NGS analysis of in vitro and in vivo samples.
$90,000 - $144,650 a yearFull-timeExpandApply NowActive JobUpdated 4 days ago - UpvoteDownvoteShare Job
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Experience in mouse ex-vivo work, immune cell culture, and advanced flow cytometry and cell culture techniques. Preferred: Master's degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field.
$97,400Full-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Expertise in one or more of the following: primary and mammalian cell culture systems, in vivo models of heart failure and/or skeletal muscle diseases, RNseq, proteomics, bioinformatics analysis.
$80,000 - $85,000 a yearFull-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Hands-on in vivo skills to perform standard procedures including rodent handling, blood collection, dosing through multiple routes (IV, IP, SC, PO), urine collection, necropsies, and tissue collection in compliance with approved IACUC protocols and AAALAC regulations.
ExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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Methods will include tissue culture, flow cytometry, single cell and spatial transcriptomics, droplet-based technologies, and genetic perturbation using CRISPR. This position is ideal for highly motivated applicants who are looking for an opportunity to further develop their wet and dry lab skills, gain knowledge in immunology, tumor biology, gene editing, single cell and spatial technologies, and aim to eventually drive their own independent research projects.
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Reporting to and partnering with the CEO, this role will lead a team of talented research scientists in Cancer Biology, Protein Therapeutics, Analytical Development, Pharmaceutical Chemistry, Formulation Development, Process Development and CMC Leadership for our Nemvaleukin alfa, IL-12 and IL-18 R&D programs.
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