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Independently operates & monitors production equipment, in accordance to procedures/batch records; including process tanks, balances, bioburden filtration assemblies, chromatography columns/skids, UF/DF equipment, data recorders and depth filter systems.
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Responsible for instrument preparation, downstream purification processing and other clean room operations per cGMP requirement under supervision. Experience in TFF skids, centrifuges, chromatography columns and systems, and/or UF/DF (ultrafiltration/ diafiltration) systems are preferred.
$20 - $27 an hourFull-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Transfers and Introduces technology of cell therapy-based and therapeutic protein processes into manufacturing collaborating extensively with Scorpion’s Process Development group to develop cGMP-compliant, clinical-scale production processes.
ExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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A high level of aptitude for cGMP biopharmaceutical manufacturing processes (upstream/downstream), including process knowledge of UF/DF Systems, Chromatography, Bioreactors, Seed Train, Disposable Technologies (SUMs, SUBs), Clean-in-Place (CIP), and Steam-in-Place (SIP.
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Work on systems including autoclaves, bioreactors, UF skids, Chromatography, CIP, WFI, and RODI.- Calibrate balances, scales, pH and conductivity analyzers, liquid and gas flow meters, levels, temperature and pressure transmitters, VCD & DO analyzers, CO2, and RH controllers.
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Operations include but are not limited to, dispensing and sampling of raw materials, buffer preparation, column packing, UF/DF, chromatography, viral inactivation and filtration, product sampling, and formulation of bulk drug substance and intermediate.
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The Company Scorpius BioManufacturing is a boutique biologics CDMO providing cGMP manufacturing, bioanalytical, and process development services for protein modalities. Protein purification: UF/DF, ion exchange, Protein A/G, HTP, HIC.
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Associates Degree with 2-3 years experience in a cGMP biologics manufacturing facility. High School Diploma (or GED) with a minimum of 3-4 years experience in a cGMP biologics manufacturing facility.
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Execute downstream technology strategies from bioreactor recovery, chromatography column purification, impurity removal, viral inactivation and filtration, UF/DF, and sterile filtration. Additional job responsibilities will include generation and maintenance of cGMP manufacturing and technical documentation, troubleshooting and/or providing technical expertise to perform troubleshooting efforts or lead investigations, ensuring staff training and compliance, execution of plant start-up commissioning and validation activities, and implement and maintain required cGMP compliant systems.
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Preference) In-depth manufacturing process knowledge, including proficient knowledge and qualification in one or more processes, intermediate suspension, centrifuge operation, chromatography, COP, CIP, filtration, UF/DF, filter press operation and facility/equipment cleaning.
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Operate, monitor and maintain all Antigen Production, Unit 2 Department equipment such as but not limited to BL-3 harvest tanks, CO2 incubator, roller racks and incubators, autoclaves, BL-3 UF skid, Biosafety cabinets, Cell Cube equipment, liquid nitrogen storage containers, spinner flasks, and biochemical analyzers.
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Experience in operating filtration units, centrifuges, filter presses and UF (ultrafiltration) systems in a cGMP or pharmaceutical setting. We are seeking a Downstream Processing Ops Lead responsible for expanding our lab-scale recovery capabilities to remove or recover micro-organisms and bioactives from broth generated at our Fermentation Research Facility in Wilmington, DE.
Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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The focus of this job is to guide the successful execution of downstream clinical and commercial manufacturing operations while ensuring cGMP compliance. Knowledge of cGMP requirements to ensure compliance.
Full-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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Subject Matter Expert in cGMP downstream manufacturing; especially with Chromatography, Column Packing, Tangential Flow Filtration (TFF), Ultrafiltration/Diafiltration (UF/DF), Nanofiltration, Formulation, Bulk Drug Substance Aliquoting.
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Bachelor's Degree with a minimum of 1-3 years experience in a cGMP biologics manufacturing facility. Demonstrates strong practical/theoretical knowledge of biomanufacturing concepts and cGMP.
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