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Our basic and translational research programs focus on cartilage and disc regeneration, fracture healing, molecular and stem cell biology, bioengineering, and musculoskeletal development.
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BS/MS in Stem Cell Biology, Molecular Biology, Genetics or a related discipline. Technical expertise in at least two of the following areas: cell based functional assays, image acquisition/analysis, molecular assays (NGS, RT-PCR, dd-PCR.
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The candidate will bring a strong understanding of cardiac biology, e.g., electrophysiology, muscle physiology, molecular biology, cell biology, echocardiography, and ideally some experience in drug discovery.
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Bone marrow and/or stem cell processing, blood banking, hematology, cell culture and apheresis. Bachelor’s degree in Medical Technology, Medical Laboratory Science, Clinical Laboratory Science, Chemistry, Biology, immunology, Molecular Biology and other related field.
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Experience with general laboratory techniques, especially basic molecular and cellular biology techniques (including but not limited to DNA and RNA isolation, PCR, gel electrophoresis, DNA assembly, bacterial transformation, mammalian cell culture, etc.
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We pursue a multi-disciplinary approach integrating data across biological scales in the brain, including molecular Chromosome-Conformation-Capture sequencing technologies, single-cell imaging, optogenetics, genome engineering, induced pluripotent stem cell differentiation to neurons/organoids, and in vitro and in vivo electrophysiological measurements.
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The Stem Cell Innovation Center (SCIC) is dedicated to pioneering advancements at the nexus of genomics, stem cell biology, and cutting- edge technologies, with a mission to expedite the translation of scientific insights into tangible therapies.
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Research in the department spans a wide range of biological problems at the molecular, cellular, tissue, and whole animal scales, and includes the molecular basis of transcription and translation, cellular signaling, development of multicellular tissues, virus structural biology, immunology, and computational biology.
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In addition, the Center has added 22 NIH-funded laboratory investigators in the last five years, recruited jointly with the Departments of Biochemistry and Structural Biology, Pharmacology, Molecular Medicine, Cell Systems and Anatomy, and Medicine.
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Performing basic stem cell culture techniques, immunohistochemistry, basic molecular biology, microscopy and data analysis. Candidates should have a solid biology background with coursework in organic chemistry, Biochemistry, molecular biology and cell biology.
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Ph. D. in cell/molecular biology, pharmacology, neuroscience, or related field with 2+ years of relevant experience. Experience with advanced cell culture techniques including culture and differentiation of induced pluripotent stem cells to neurons, microglia, or astrocytes to evaluate mechanisms of neurodegeneration.
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Knowledge of molecular biology, mouse handling, cell culture, and immunology techniques. The project involves the study of clonal hematopoiesis, a precancerous condition that is related to aging and inflammation, with an emphasis on the role of DNA methylation and demethylation in stem cell function.
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Bachelor’s or Master’s degree in life sciences, e.g., Biochemistry, Molecular Biology, Cell Biology, Developmental Biology, Pharmacology, Pharmaceutical Sciences, or related field.
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We use a range of tools and techniques include advanced molecular biology, biochemistry, reconstituted systems, stem cell cultures, and genomic sequencing. Extensive expertise in molecular biology and biochemistry.
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Experience with tissue culture or molecular biology techniques. The outcomes of interest of the current study include newborn/infant stem cell characteristics, and newborn, infant and child body composition (adiposity) and metabolism function.
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