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Develop and execute efficient strategies for target identification, prioritization and validation; review, propose, initiate, and implement new pre-clinical therapeutic antibody drug discovery and development programs in the field of Immunology and Inflammation.
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The scientist will evaluate, develop, and optimize computational methods to analyze next-generation sequencing datasets in support of our drug discovery and development programs, and will produce robust bioinformatics pipelines that can be operated on high-performance computing clusters and in the cloud.
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The scientist will collaborate with biologists and data analysts across diverse therapeutic areas, such as Oncology, Immunology, Infectious Diseases & Vaccines, Neuroscience, and Pharmacokinetics.
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Calibr-Skaggs was founded on the principle that the creation of new medicines can be accelerated by pairing world-class biomedical research with state-of-the-art drug discovery and development capabilities.
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Clinical Bioinformatics & Exploratory Analytics, as a part of the Clinical Data Science organization, supports drug development and other business use cases across Gilead by providing data analytical, engineering, and visualization solutions to enable scientific and other business exploration and decision-making, including statistical analysis, genomic data processing and analysis, general machine learning and deep learning, and other technical infrastructure.
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Experience in drug discovery process accumulated in prophylactic and therapeutic vaccine development. You will work closely with the Viral Vaccine Director to develop and apply interdisciplinary approaches to understand the mechanisms of action of different types of RNbased viral vaccine drug substance and lipid nanoparticle drug products and participate in the development of next-generation RNA vaccine prototypes.
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Engages as a matrix team member on protocol teams as a scientific partner in the drug development process. Statisticians develop collaborative relationships and work effectively with the Global Biometric Sciences (GBS) Lead, the GBS Planning and Execution Lead, statistical programmers, external partners, medical monitor, protocol manager, data manager, PK scientist, and other members of the study/indication team.
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At least 8 years of relevant drug development experience, either within industry or as a clinical investigator/physician scientist in academia, or equivalent experience. The Executive Medical Director will oversee the direction, planning, execution, and interpretation of clinical trials in autoimmune/immunology indications (e.g. Rheumatology) and data collection activities for multiple programs in the development portfolio.
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The candidate will serve as the analytical representative on the CMC team for early development programs and as such would be responsible for developing timelines and executing analytical activities required for drug substance and drug product development.
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DescriptionJanssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies, is recruiting for a Principal Scientist, Computer-Aided Drug Design (CADD, Computational Chemistry) located in San Diego, CA (La Jolla area.
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Cross-functional Collaboration: Collaborate closely with other departments, including Biologics Discovery CMC, Drug Product Development, Drug Substance, Drug Delivery, Operations, Quality, Business and Clinical Development to ensure seamless product development.
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For the Principal Research Scientist I position, we are seeking a highly motivated, experienced analytical scientist and leader to lead a team of analytical scientists supporting the development of New Chemical Entities (NCEs) drug substance and drug product from pre-clinical through Phase III under GLP and GMP guidelines.
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Calibr-Skaggs' drug development portfolio spans a broad range of human diseases, including cancer, autoimmunity and inflammatory diseases, metabolic and cardiovascular diseases, infectious and neglected diseases, as well as age-related and degenerative diseases.
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Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and CGT products.
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The Manufacturing Technician/Specialist/Scientist assists in the manufacturing processes and process development activities in collaboration with staff. Minimum Requirement: Bachelor's degree with 7+ years experience in relevant scientific area (e.g., GMP: chemistry, biology, chemical engineering, analytical chemistry, biotechnology; ECTL: cellular biology, molecular biology, immunology, biochemistry.
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