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Avidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs). Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies.
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Execute lab procedures, including tissue lysis, ELISA, Western Blot, RNA/DNA extraction, qPCR. Experience in tissue dissection and tissue preparation for histology, RNA, DNA, and protein analysis.
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Experience in standard cellular and molecular biology techniques (Cell culture, ELISA, Cell-based assays, Immunofluorescence, Western blotting, Microscopy, RNA/DNA isolation, qPCR) RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein.
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Familiarity with commercially available NGS kits for targeted and non-targeted RNA & DNA sequencing. Generate NGS libraries for sequencing of RNA and cell-free DNA. Familiarity with commercially available NGS kits for targeted and non-targeted RNA & DNA sequencing.
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Experience with cellular and molecular biology techniques (including molecular cloning, RNA extraction, PCR, qPCR, western blotting, and microscopy). Associate Research Scientist - RNA Biology , Aging & Cancer.
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Work closely with RNA production, LNP/RNP formulation, and in vitro and in vivo team members. Characterize the RNA/RNP encapsulated LNPs for their size, zeta potential, morphology, encapsulation efficiency, integrity, and stability using relevant assays (DLS, TEM, Ribogreen, CE, AGE, PAGE, UV-VIS, HPLC, etc.
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Cell culture, RNA biochemistry, protein purification, preparation of libraries for high-throughput sequencing, and other duties as assigned. Experience working with RNA, protein purification, bioinformatics and/or mouse work would be a plus.
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Current CPR and Automated External Defibrillator (AED) and First Aid certifications are required or must be willing and able to become CPR, AED, and First Aid certified.
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Develop other molecular biology-based assays using techniques such as cloning, DNA/RNA/protein extraction and RT-PCR. Highly experienced in protein assay development such as western blot/JESS, flow cytometry, ELISA, AlphaLisa, and.
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This Principle Scientist will collaborate closely with various research groups, scientists, and upper management to pioneer world-class Next Generation Sequencing technologies catering to RNA, DNA, epigenetics, and microbiome analyses.
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Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and ELISA. Some training may be provided.
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Sail's platform combines first-in-class programmable RNA technology (Endless RNATM or eRNA), and an industry-leading platform of programmable nanoparticles, utilizing natural components, to unlock comprehensive programming of medicines for the first time.
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Experienced in tissue sample processing for molecular biology biomarkers such as DNA, RNA extraction. The Senior Research Associate will be a key player in driving genomic medicine pipeline project through target validation, candidate selection and IND-enabling phases using in vitro, in vivo and ex vivo studies.
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Candidates with previous laboratory experience in DNA/RNA purification, PCR, ELISA, and Western Blot will be preferred. · Tissue processing such as DNA/RNA extraction. Candidates with previous laboratory experience in DNA/RNA purification, PCR, ELISA, and Western Blot will be preferred.
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This role will focus on MLOps for training in large scale ML models of RNA and/or DNA. You will be part of a dynamic, cross-functional team responsible for developing and deploying machine learning models for sequence design.
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rna job
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