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We are seeking a highly motivated Bioinformatics Scientist who wants the opportunity to significantly impact the growth and success of our RNA genomics programs. The successful scientist is expected to be self-motivated, detail oriented, have an understanding of RNA biology, and have the ability to work cross functionally between departments.
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Experience with molecular biology techniques and analysis (DNA/RNA purification, qPCR, ddPCR, etc.) By merging innovations in AI and RNA technology to generate and analyze hundreds of billions of therapeutic possibilities, Shape TX is developing breakthroughs in RNA editing, next-generation AAVs, and disruptive gene therapy manufacturing.
$82,000 - $124,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Develop novel bioinformatic analyses for interrogating RNA biology and integrating across our assays. Execute existing standard analysis pipelines on Next Generation Sequencing (NGS) data using the AWS cloud platform.
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Experiments include, but not limited to qRT-PCR, western blotting, mammalian cell culture and cell line maintenance, DNA/RNA extraction, electrophoresis, ELISA, proliferation, and migration assays, Ca2 imaging, isolated and pressurized arterioles from mouse brain, patch-clamp electrophysiology on isolated cells, in vivo two-photon microscopy.
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Our team is looking for an enthusiastic scientist to join our in vivo RNA delivery program. Flow cytometry and cell sorting, qRT-PCR and immunofluorescence analyses, ELISA. Our team is looking for an enthusiastic scientist to join our in vivo RNA delivery program.
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Background in molecular biology techniques such as cloning, site-directed mutagenesis, DNA and RNA isolation and purification, sequencing, RT-PCR, and qPCR. Rescue and characterize pseudo viruses and/or RNA viruses.
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Experience in molecular biology techniques, including primer design, PCR, plasmid construction, sequencing, DNA or RNA purification. Applying expertise in CRISPR gene editing technology, work with R&D team to develop RNA LNP formulations for customers’ early phase drug development project, and carry out in vitro assays to evaluate the formulations’ performance.
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The incubent will work alongside subject matter experts in the fields of cell biology and biomedical engineering, and perform functional and targeted assays to describe the neurobiology of the model systems, such as RNA isolation/sequencing, ELISA, and other in vitro assays.
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Robust experience in RNA sequencing (bulk and single-cell) and proteomics methods. We apply a multidisciplinary approach to our research and actively collaborate with virology, cell biology, genomics, proteomics, microscopy, and data science teams at the CZ Biohub San Francisco.
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Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and ELISA. Some training may be provided.
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You will support R&D with single-cell and bulk RNA and DNA analysis and pipeline development while using and promoting best practices for coding (Python/R) and reproducible research. The Staff Scientist, Bioinformatics is responsible for collecting product requirements and designing and developing NGS analysis pipelines to meet those requirements.
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Standard immunological techniques - Flow cytometry, ELISAs / Elispot, fluorescent microscopy Molecular biology skills - PCR, rt-PCR and RNA work, basic cloning Three published first authored papers in immunology.
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Essential qualifications:- Experience in basic molecular biology techniques, including: PCR, DNA/RNA extractions, solution preparation- Good hands in lab and dedication to hands-on laboratory work- Ability to lead a project independently and problem solve as needed- Ability to work well with others in a team environment- Ability to multi-task and prioritize in an environment with multiple demands and ongoing projects- Excellent organizational skills and a strong attention to detail.
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The candidate will work in close collaboration with different research groups and scientists, as well as with Zymo upper management to develop (from concept to commercialization) world-class Next Generation Sequencing technologies for RNA, DNA, epigenetics, and microbiome analyses.
$100,000 - $180,000 a yearExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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This individual will plan and perform experiments, which entail the use of cutting-edge molecular techniques, such as single cell RNA, DNA and ATAC sequencing. DNA/RNA extraction, massively parallel sequencing.
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rna job
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