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We seek a motivated and collaborative team member with molecular cloning, protein expression, purification, and characterization experience to join our Redwood Shore site's Discovery Protein Science group.
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Biotech manufacturing, Cell Culture, depth and tangential flow filtration, column chromatography, protein purification and formulation, buffer and media operations, SOP. Knowledge of biotech manufacturing processes and equipment, including cell culture, depth and tangential flow filtration, column chromatography, protein purification and formulation, and buffer and media operations.
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Proficient in all aspects of modern peptide synthesis, protein bioconjugation, peptide and protein purification and analysis. Principal Scientist, Peptide Protein Chemistry.
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The Icosavax preclinical group, based in Seattle, WA is seeking a Director, Vaccines Research with a strong background in vaccine research, antigen discovery and development, and protein biochemistry with prior experience in protein expression, purification and characterization to help progress our vaccine candidates through preclinical pipeline into early clinical development.
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This work will require a number of biochemical and biologic techniques including (but not limited to): PCR; DNA and protein gel electrophoresis; Western blotting; standard cell culture; flow cytometry; transfections; DNA/RNA extractions; protein purification; buffer preparation; and microplate assays.
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We are seeking a Scientist to join our Downstream Process Development Department - Process Sciences in Gaithersburg, MD. Qualified individuals will play a role in downstream process development; scale up, new technologies, and technical support of cGMP manufacturing for protein particle vaccines.
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Experience in molecular biology, protein engineering, protein purification, Surface Plasmon Resonance (SPR), and tissue culture. Experience in molecular biology, protein engineering, protein purification, Surface Plasmon Resonance (SPR), and tissue culture.
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Perform expression and purification of recombinant viral protein and human monoclonal antibodies and fragments ( E.coli, insect cells, mammalian cells) via affinity chromatography and FPLC-based size exclusion and ion exchange.
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Experience with FPLC systems and with affinity, IEX and SEC protein purification methods is desirable. Experience with recombinant protein expression and purification using mammalian cell lines and/or E. coli.
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Transfers and Introduces technology of cell therapy-based and therapeutic protein processes into manufacturing collaborating extensively with Scorpion’s Process Development group to develop cGMP-compliant, clinical-scale production processes.
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Solid working knowledge of various manufacturing platforms (Microbial fermentation process, IB recovery and refolding, CHO cell culture and purification, Pegylation, PEGylated protein purification etc.
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This position will report to the Technical Operations Department and will support the manufacture of HPV Gardasil as part of a multidisciplinary team, the candidate will have a fundamental knowledge of fermentation and cell culture, protein chemistry and purification, analytical techniques and/or laboratory operations.
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Experience with different protein purification approaches such as affinity (His-tag, Fc-fusion), cation- and anion-exchange, size-exclusion chromatography (SEC). Performs protein engineering, production, and purification from E. coli, insect cell, and mammalian expression systems.
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Knowledge of biotech manufacturing process and equipment including cell culture, depth and tangential flow filtration, column chromatography, protein purification and formulation and/or buffer and media operations.
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Experience working with protein purification. Join our Process Development Team in using a variety of fermentation techniques, purification techniques, and characterization methods to support commercial and bench scale pharmaceutical processes.
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