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The Research IT Business Analyst will partner with scientists to define and implement technology solutions that propel Biogen's drug discovery initiatives across gene therapy, small molecule therapeutics, protein therapeutics and ASO technologies.
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Experience in drug discovery and an understanding of drug-protein interactions. Perform low and high-throughput screens using the Biacore 8K SPR for hit discovery, medicinal chemistry SAR support, and detailed evaluations of protein-antibody and protein-peptide interactions.
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Evaluation and reporting of clinical and anatomic pathology in support of drug discovery and development. · Collaborate with drug discovery and development scientists in the design and execution of efficacy, investigative pathology and mechanistic studies, including experimental animal models (e.g., disease models, genetic models.
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The ABC site, based in Worcester, MA, offers a unique setting where GM, Biologics drug discovery, development and manufacturing coexist in one location. · Strong RNA biology knowledge including genetic element (UTRs, codon, structure, IRES) optimization for enhanced protein translation.
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Ideal candidates should have a combination of experience and desire to gain expertise in drug discovery areas related to cellular and molecular biology, genome engineering, protein engineering, functional screening systems, cellular profiling approaches, protein stability and homeostasis, or related areas of focus.
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With protein designers, biologists, and other members of the drug discovery team. platform, we aim to minimize risks in drug development, accelerate the drug discovery process.
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Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.
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Must possess a solid understanding of protein chemistry and biochemistry, particularly as related to biologics drug development. Our scope includes AbbVie's diverse pipeline of innovative therapeutic biologics medicines, including monoclonal antibodies, antibody drug conjugates (ADC), and other novel modalities, and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch.
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We are at the forefront of innovation, leveraging state-of-the-art tools to accelerate drug discovery, protein engineering, immunogenicity prediction and other critical areas in the life sciences at Takeda.
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FogPharma's discovery engine creates Helicon™ therapeutics, which are a new generation of ultra-diverse, highly tunable peptide drugs capable of modulating virtually any protein implicated in disease.
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Our multidisciplinary team of brain tumor specialists and scientists are accelerating drug discovery and precision medicine in neuro-oncology to identify the most promising first-in-class therapies for brain tumor patients.
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The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery. biology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR , Flow Cytometry.
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Demonstrate proficiency with sterile cell culture, cell-based assays (CTG, apoptosis) and molecular biology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR, Flow Cytometry). transductions, RNA and protein preparation from cells and tissue, RT-PCR, western blotting, and.
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The candidate must have a strong knowledge of protein biochemistry & biophysics; familiarity with biologic drug product characterization & control strategies; and experience developing drug product manufacturing processes including lyophilization and/or combination products.
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We leverage our expertise in structure-guided drug design to develop first-in-class or best-in-class oral small-molecule and protein therapeutics, led by the efforts of our team of expert scientists in our Discovery Center of Excellence in Birmingham, Alabama.
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