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Bachelor’s Degree in Chemistry, Biochemistry, Bioengineering, Chemical Engineering or. Our tools portfolio includes our proprietary, serum-free and protein-free, fully defined CryoStor freeze media and HypoThermosol shipping and storage media, ThawSTAR family of automated, water-free thawing products, evo cold chain management system, and Custom Biogenic Systems high-capacity storage freezers.
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Ph. D. (or equivalent experience) in mass-spectrometry based proteomics, analytical chemistry, chemical biology, or related discipline. This position will help discover novel small-molecule ligands of protein targets through the execution of screens using our novel mass spectrometry-based proteomics platforms.
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BSc or MSc in Pharmaceutics, Chemistry, Biophysics or Biochemistry preferred, with >7 years of industrial experience; or PhD in Pharmaceutics, Chemistry, Biophysics or Biochemistry with >5 years of relevant experience.
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This role demands expertise in food science, material science, polymer chemistry, and protein chemistry, along with a keen curiosity and willingness to explore beyond traditional disciplinary boundaries (think sensory testing, food science, etc.
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Prior hands-on experience with nucleic acid and protein purification, molecular biology, bacterial genetics, and assay development are preferred, but any exceptionally creative and driven individual will be thoroughly considered.
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Drive the CMC elements related to bioconjugation throughout the product life cycle using technical expertise in conjugation chemistry and downstream unit operations including tangential flow filtration, dead-end filtration, and protein chromatography.
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This position will report to the Technical Operations Department and will support the manufacture of HPV Gardasil as part of a multidisciplinary team, the candidate will have a fundamental knowledge of fermentation and cell culture, protein chemistry and purification, analytical techniques and/or laboratory operations.
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Understanding of the basic principles of protein chemistry and/or drug product process is required. This position is required to conduct studies to enable Drug Product characterization activities, including combination products at high protein concentration, as well as commercial products.
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We are expanding our capabilities in informatics across multiple drug discovery platforms, including DNencoded library (DEL) screening, peptide-display discovery, support for RNbased therapeutics, parallel medicinal chemistry (PMC), targeted protein degradation, and high-throughput screening (HTS.
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The Principal Scientist is a senior scientific role tasked with working closely with the group Director to define group strategy and to lead a team of scientists in solving complex analytical problems at the interface of biology, chemistry, and lab informatics disciplines to enable development of biologics active pharmaceutical ingredients (APIs.
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Visit us: The Therapeutics Discovery organization within Janssen R&D is continuing to build key scientific expertise in computational and medicinal chemistry, screening, and pharmacology to partner closely with our outstanding therapeutic area scientists to develop groundbreaking new medicines in the areas of Oncology, Immunology, Neuroscience, Cardiovascular, and Retina.
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Solid knowledge of medicinal chemistry principles, including DMPK, as well as the understanding of IP and its analysis is expected. Acts as a resource and provides work direction for other research personnelKnowledge, Experience & Skills:Essential:Experience in a broad variety of computational techniques is essential, particularly molecular docking, pharmacophore development, library design and analysis, machine learning methods, and protein-ligand simulation.
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Liaison and coordinate with scientists in areas of Molecular Modeling and Medicinal Chemistry to drive drug design and demonstrate leadership in strengthening our alignment with Computational Drug Discovery team.
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In this role, you will play a pivotal part in QPS' continued expansion of our bioanalytical capabilities to support small molecule, antibody drug conjugate, protein, and gene therapy drug development.
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Comprehensive knowledge and understanding of protein folding and structure-activity relationship, protein/peptide chemistry, chemical and physical stability. Knowledge of fundamental principles of pharmaceutical science essential for the development of injectable dosage forms of small molecule, protein and peptide therapeutics.
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