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Experience with protein purification using an AKTA system and protein characterization using HPLC (analytical SEC), SDS-PAGE, and mass spectrometry. Through the application of our proprietary chemoproteomics platform merged with innovative biology and medicinal chemistry, we are modulating protein function in previously unidentified ways to push the limits of drug discovery.
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Skilled in the latest analytical technologies and methodologies commonly used in the analysis and characterization of biologics, carbohydrates, conjugates and small molecule drug candidates and successful track record of method development trouble shooting and validation, e.g. UV-Vis, various modes of HPLC, CE, SDS-PAGE, icIEF, LCMS, GCMS, SEC-MALS, enzyme kinetics, colorimetric and fluorescent plate-based assays, ELISA, Western Blot, etc.
$169,000 - $185,000 a yearFull-timeExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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Responsible for day to day running of experiments and data analysis in the protein chemistry laboratory. E.g., HPLC, FPLC, Western Blot, SDS-PAGE, Protein Simple Wes and other analytical tools.
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3-5 years of analytical experience in protein/peptide separations by CE-SDS and/or cIEF in pharmaceutical or biotechnology companyScientific and practical knowledge of protein characterization for protein therapeutics including monoclonal antibodies and glycoproteinsAbility to take initiative in problem solving and consistently bring independent, scientific approach to method developmentThe duties of this role are generally conducted in an lab environment.
Full-timeExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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Knowledge and experience with large scale protein purification, nucleic acid purification, and other chromatography application processes. MS degree in biotechnology, analytical chemistry, material science, polymer science, chemistry, chemical engineering, biochemistry or related field.
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Bachelor’s in Molecular Biology, Synthetic Biology, Biochemistry, Structural Biology, Protein Chemistry, or similar field. Protein purification (AKTA, HPLC, SDS-PAGE, BLI/SPR.
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You will work collaboratively with protein designers, biologists, computational scientists, and other drug discovery team members. Molecular biology (primer design, Gibson, Golden Gate, Ligation, CRISPR.
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RequirementsWhat You Need to Achieve It: Minimum of a M.S./Ph. D. in Analytical Chemistry, Biochemistry, Protein Chemistry, or other related field with 8 years of direct CGMP experience within the biotechnology, medical device, biopharmaceutical, or other similarly regulated industry.
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A strong background in protein chemistry will be essential to perform and troubleshoot techniques such as HPLC, SDS-PAGE, cell-based bioassays, capillary electrophoresis, SDS-PAGE, ELISA, and standard compendial assays.
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Experience in biochemical techniques (protein quantification, SDS-PAGE gel, enzyme assays) Education & Experience: Masters in Biochemistry, Biological chemistry, Biotechnology, or a related field with 1+ years of practical lab experience in industry or academic/institute R&D OR Bachelors degree with 5+ years of related experience.
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Biochemistry and protein chemistry experience (flow cytometry, FACS, ELISA, western blotting, SDS-PAGE, etc.) Biochemistry and protein chemistry experience (flow cytometry, FACS, ELISA, western blotting, SDS-PAGE, etc.
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Advanced technical expertise in bioanalytical and physicochemical methodologies used to characterize protein therapeutics (e.g., HPLC, UPLC, and electrophoresis). M.S. in biological sciences, biochemistry, analytical chemistry, or closely related field.
Full-timeExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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Typical analyses for release and stability include appearance, pH, MFI, RP-UPLC, KF (Moisture Content), HPLC/UPLC (various detectors), CE-SDS, icIEF, Protein Concentration by UV/Vis or SoloVPE, SEC and Specific Activity, and LC-MS.
Full-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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Advanced technical expertise in analytical methodologies used to characterize protein therapeutics including CE-SDS, cIEF / icIEF, HIC, SEC, IEX, RP, HILIC, MS, etc. Analyze late-stage protein-based therapies with advanced techniques such as capillary electrophoresis, liquid chromatography, mass spectrometry, as well as other methods.
Full-timeExpandApply NowActive JobUpdated 19 days ago - UpvoteDownvoteShare Job
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Strong background in protein chemistry and experience troubleshooting analytical results. Demonstrated success working with techniques such as HPLC, SDS-PAGE, cell-based bioassays, capillary electrophoresis, SDS-PAGE, ELISA, and standard compendial assays.
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