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The team strives to deliver compelling preclinical, clinical, and translational data packages providing confidence in the dosing strategy, tolerability profile, and therapeutic efficacy of our candidate drugs to support investment in late-stage clinical development, leading to drug approval.
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Preclinical Safety and Translational Sciences (PSTS) division of J&J Innovative Medicine R&D is an integrated end to end organization encompassing bioanalysis, drug disposition and metabolism, in vivo sciences (IVS), investigative toxicology, pathology, science operations and data sciences, and toxicology, with a focus on understanding the disposition and potential risks of candidate therapeutics across all therapeutic areas and modalities, and covering the entire portfolio.
$95,000 a yearFull-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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The CSO joins in a breakthrough year for the company as it has refined its therapeutic area focus and gained significant business momentum. · Lead early discovery research from target identification through preclinical assessment, including collaborations with other companies and academia.
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GemPharmatech is a global company providing high-quality products and model systems for preclinical discovery, testing, and development of new drugs and therapeutic solutions. GemPharmatech is a leading one-stop service center for production, distribution, phenotyping of genetically engineered mouse models (GEMMs), contract research and preclinical testing for partners across the world.
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Wave is looking for a top talent with a strong interest in biotech drug development to join a growing RNA medicines company with multiple clinical and preclinical programs in muscle, liver, and neurological diseases, as well as a novel and best-in-class discovery and drug development platform.
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Develop, qualify, and validate (as appropriate) bioanalytical assays (expressions assays including mRNA and protein [ELISA/IHC], anti-AAV capsid nAb, CTL IFN-γ ELISPOT, IgG/IgM, biodistribution and shedding) for all programs and define science-driven, phase appropriate, and risk-based analytical development strategies to support the development candidate during discovery through preclinical evaluation (including GLP) and clinical development advancement.
Full-timeExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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Lead and manage a group of ~80 scientists responsible for conceiving and developing new gene therapeutic concepts, AAV vector design and development, and translational research to advance the concepts toward clinical testing Partner closely with members of the Rare Disease Unit (RDU) and members of AstraZeneca’s Discovery Sciences genomic medicine group to identify, implement and progress new gene therapy projects.
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The Toxicologist will collaborate with external vendors, the internal preclinical pharmacology and toxicology team, and other stakeholders across the company to ensure efficient processes that scale with Verve's continued growth.
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Develop collaborative relationships with Key Opinion Leaders (KOLs) in therapeutic areas of interest to establish foundational preclinical data sets providing new insights and pathways for therapeutic intervention.
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This position will partner with functional sub-team leaders to lead project management activities for a cell therapy program sub-team, guiding the sub-team through preclinical and clinical development.
$145,000 - $175,000 a yearFull-timeExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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Founded in 2015, the company has built a portfolio of 20+ drug development programs ranging from preclinical to late-stage development in multiple therapeutic areas including genetic dermatology, precision oncology, cardiology, endocrinology, neurology, pulmonology, and renal disease, with two approved drugs.
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The candidate will develop and lead implementation of strategies and assays to profile siRNA using biochemical and in vivo assays across a range of therapeutic areas. Interface closely with internal research, preclinical and development teams to drive RNA delivery and design innovation meeting corporate timeline objectives.
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Act with urgency to identify, screen, monitor and evaluate business development opportunities with life science and biotech companies in China with a focus on cutting-edge science across all therapeutic areas (preclinical through pre-proof of concept in humans) and modalities to enhance and expand the pipeline of R&D department.
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RequirementsMD or PhD from an accredited institution with profound experience in the field of Clinical Development, TMCP and specialist in the respective Therapeutic Area. Expert knowledge in preclinical and clinical drug development (Phase I/II/III) with at least ten (10) years of experience in clinical development, exploratory clinical, and clinical pharmacology in the pharmaceutical industry.
$200,000 - $347,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and Cell & Gene Therapy products.
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