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Conduct in vitro pharmacology experiments for preclinical contract research. Minimum of a bachelor’s degree in biology, biochemistry, pharmacology, or closely related fields; Master’s degree with working experience is preferred.
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Education: Hold a BSc/BA or higher degree in biology or a relevant scientific field, enabling a deep understanding of the complexities of preclinical pharmacology research. PharmaLegacy, a leading preclinical pharmacology Contract Research Organization, is seeking a highly motivated and experienced Director of Business Development to join our team.
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The Laboratory Animal Research Technician will join a staff of highly trained scientist and technicians, and state of the art facilities to support our clients' toxicology, safety pharmacology, and inhalation research programs in our animal care division.
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PhD or PharmD with relevant expertise in clinical pharmacology or pharmaceutical science is required. This position will work in close collaboration with different functions, including preclinical toxicology, preclinical pharmacokinetics, translational medicine, clinical, operations, and regulatory affairs.
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Identify, establish, and monitor in vivo pharmacology, pharmacokinetic (PK), and pharmacodynamic (PD) studies at CROs. Report and present scientific findings at appropriate scientific venues. As the Principal Scientist, Research you will effectively design, conduct, and analyze preclinical experimental data to support our ENHANZE drug delivery platform and alliance partners.
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Develop and oversee implementation of clinical pharmacology studies from protocol development to final study reporting, in collaboration with cross-functional study team members, including Clinical Operations, Biometrics and Regulatory Affairs, as well as CRO partners.
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The Preclinical pharmacology team works closely with the Medicinal Chemistry, High Throughput Screening and Protein Engineering modules. Preclinical pharmacology informs how drug candidates will behave in humans.
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Perform in vitro studies to assess the use of intestinal organoids from preclinical species (rat, dog and non-human primate) to predict human toxicities caused by small molecule oncotherapeutics.
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Expert skills in performing in vivo pharmacology and mechanistic studies in preclinical in vivo models including dosing of various routes, tissue sampling and dissection, assay development, minor surgeries and physiological assessments of behavior or health.
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Lead preclinical pharmacology including in vitro and in vivo assay development and execution across the organization. A PhD or equivalent with a focus on pharmacology, neuroscience, molecular biology, or cellular biology.
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Our client offers preclinical services for drug discovery, focused on the use of nonhuman primates to determine pharmacokinetics, pharmacology and toxicology of small molecules and biologics.
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You will work with experienced pharmacometricians, Preclinical Pharmacokinetics, Drug Metabolism, Toxicology, and Clinical Pharmacology colleagues to provide inputs to overall product development plans and to address research and development objectives and issues.
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7 or more years of experience within pharmacovigilance, clinical pharmacology, preclinical research, toxicology and/or biomarker validation (especially in industry) required. Grow CSPV's connection to toxicology (MSRL) and Precision Medicine beginning at the start of preclinical development.
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Head up the development team starting at the time of CTA/IND or proof of concept depending on the program, including all functions: clinical, regulatory, biostatistics, program management, clinical operations, tech ops/CMC, clinical pharmacology, research, and preclinical development, to design and execute clinical development plans for assigned projects.
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Responsible for all areas of preclinical research and development, including generating pharmacology and toxicology data, preclinical trial strategy and design, preparation of the preclinical development plan to support successful INDs, and contribution to regulatory strategy.
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