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Strong working knowledge of biochemistry, biophysics, ADME, pharmacokinetics, biology, pharmacology, DMPK, and toxicology. Head of Medicinal Chemistry and Head of the Novo Nordisk (NN) Small Molecule Research Unit. Will interact and closely collaborate with other Small Molecule Unit Scientists (chemists, biochemists, biophysicists, crystallographers), Data Science & Innovation (DSI) computational chemists, Global Drug Discovery (GDD) biology, Global Research Technologies (GRT), GDD Drug Metabolism and Pharmacokinetics (DMPK), cellular biology, pharmacology and translational medicine teams globally.
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Provide thorough understanding of pharmacokinetics, pharmacology, toxicology, drug design, use of in silico tools, ability to interpret in vivo results, drug discovery process, purification techniques, and ability to analyze target compound spectra obtained by analytical instruments to characterize compounds such as nuclear magnetic resonance (NMR), infrared spectrometry (IR), mass spectrometry (MS), and elemental analysis.
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Perform quantitative LC-MS/MS (Liquid Chromatography Mass Spectrometry) analysis of small molecules from various bio-matrices in vivo and in vitro to support PK/PD, ADME, efficacy and exploratory toxicology studies.
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QPS, LLC has an opening for a Research Scientist in the Bioanalytical unit of QPS’ Distribution, Metabolism, Pharmacokinetics (DMPK) department. Since its inception, QPS has been assisting pharmaceutical, biotechnology and medical device companies with their drug development efforts by providing a full range of Neuropharmacology, DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II – IV Clinical Research services.
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Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development.
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This position will work in close collaboration with different functions, including preclinical toxicology, preclinical pharmacokinetics, translational medicine, clinical, operations, and regulatory affairs.
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Develop and maintain collaborative relationship with colleagues within the department, internal stake holders (i.e., DMPK, toxicology, biology, translational medicine, medical, clinical, biometrics, regulatory, clinical operations, CMC, etc.
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The successful candidate will utilize their strong knowledge in ADME to equally partner with team members within medicinal chemistry, toxicology, pharmacology, as well as with CMC, clinicians and clinical development team to drive programs forward.
$156,500 - $232,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Additional representative responsibilities will include, but not necessarily be limited to, the following: Act as the primary representative for toxicology at cross-functional project teams, collaborating with subject matter experts in discovery, bioanalysis, pharmacokinetics, clinical development, CMC, and program management to drive the overall development strategy and timeline of candidate molecules.
$165,000 - $231,667 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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PhD, PharmD or equivalent in Pharmacokinetics, Pharmacology, Bioanalytical or related field with at least 5+ years of experience in Clinical Pharmacology, DMPK or related disciplines required. Knowledge of pharmacokinetics and pharmacodynamics (PK/PD) and DMPK principles.
$150,000 - $190,000 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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12+ years of experience in the biopharma industry in non-clinical development (toxicology, pharmacology, pharmacokinetics, bioanalytical sciences, or related discipline) Oversee and provide strategic direction for Toxicology/Pathology, BioAnalytical/DMPK, Biomarkers, and Clinical Pharmacology teams to ensure robust support for clinical development programs.
$265,000 - $300,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Frontage Laboratories Inc. is an award winning, publicly listed (HKSE), full-service CRO/Contract Research Organization operating over 25 state-of-the-art laboratories across the US, Canada and China, and growing over 30% YOY. Our core competencies include drug metabolism, pharmacokinetics/ pharmacodynamics (PK/PD), safety and toxicology, bioanalytical services, chemistry and manufacturing controls for drug development, and core laboratory services for clinical trials.
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Our client offers preclinical services for drug discovery, focused on the use of nonhuman primates to determine pharmacokinetics, pharmacology and toxicology of small molecules and biologics.
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This position reports to the head of clinical pharmacology and DMPK and liaises with clinical development, clinical operations, non-clinical pharmacology and toxicology, and drug discovery to execute activities for advancing the development pipeline.
$198,000 - $220,000 a yearExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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D. or equivalent training in pharmacokinetics, pharmaceutical sciences, or related disciplines with 5 years of clinical pharmacology industry experience or M.S. with 10 years of relevant experience.
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