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Basic science knowledge using advanced techniques in one or more fields encompassing molecular biology, immunology, bioinformatics, genomics, protein isolation and characterization, Western, IP, 2-DIGE, ELISA, immunofluorescence, confocal microscopy, RNA isolation and characterization, qPCR, oligo-arrays, in vivo imaging, cell culture and transfection.
$65,000 - $80,000 a yearFull-timeExpandApply NowActive JobUpdated Yesterday - UpvoteDownvoteShare Job
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Specific projects include in vitro and in vivo studies to determine the preventative and therapeutic activities of various naturally occurring and synthetic compounds, identify the mechanism of action and assess the safety/toxicity of the agents.
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Extensive knowledge of cell therapy concepts and exploration, including in vitro and in vivo study experience. Design and perform a variety of in vitro, ex vivo and in vivo experiments spanning multiple programs to assess cell therapy products' function and potential efficacy: average expected time at the bench 70.
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Three Postdoctoral Associate positions are available for motivated individuals to join a dynamic multidisciplinary research team at Scripps Research to study neuroimmunological and neuroinflammatory aspects of substance abuse, neuroAIDS, Alzheimer's, and their detrimental interactions, with in vivo, biochemical and genomic strategies including gene expression analysis by single cell RNSequencing and ATAC-Seq, viral vectors and related techniques.
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Other College core facilities support advanced microscopy and imaging, laser microdissection, multispectral imaging, and in vivo imaging. The successful candidate will be expected to establish a competitive, extramurally funded, research program in immunology that contributes to the research mission of the Department of Pathobiology, College of Veterinary Medicine, and Auburn University.
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Experience independently working with endothelial, myeloid and tumor cell culture, DNA and RNA isolation from culture cells and from tissues, immunoblotting and quantitative RT-PCR for genes and proteins that regulate myeloid cell adhesion, migration and gene and protein expression in vitro and in vivo.
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Reporting to the VP, Disease Biology & Translational Science, this individual will be responsible for helping to establish and expand the company's capabilities for preclinical in vitro and clinical ex vivo disease pathobiology establishing in vitro/ex vivo models to interrogate complex disease models to rank and screen our therapeutic candidates and establish the drug's mechanism of action for multiple indications.
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Responsible for data review, analysis and interpretation of in vitro and in vivo results, and troubleshooting issues related to drug discovery projects. A strong background in immunology drug discovery.
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Expertise with mouse handling, in vivo rodent models, multi-color flow cytometry, isolation and culture of primary human and mouse cells and cell lines, cell engineering, scRNseq, and/or bioinformatics analysis is also preferred.
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The Contractor will, independently and with minimal supervision, conduct in vitro, in vivo, and environmental sample testing by qualitative and quantitative real-time PCR and other methods for the identification of infectious disease of concern to the military, public health, and Force Health Protection.
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The Research Specialist will provide technical support for both in vivo and in vitro model systems used by the Principal Investigator and Post-Doctoral Fellows in a translational lung biology laboratory.
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The Jackson Laboratory in Sacramento, CA has an excellent opportunity for an In Vivo Scientist to join the Product Development team! QualificationsIndividuals with a Ph. D. (and/or M.D.) in oncology, immunology or animal pharmacology and a minimum of 4 years of experience in a contract research laboratory, pharmaceutical industry, or equivalent experience.
$97,336 - $130,000Full-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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The successful candidatewill conduct multidisciplinary in vitro and in vivo research with a variety ofapproaches including biochemical assays, western blotting, immunocytochemistry,RT-PCR, Elisa, confocal microscopy, and neural cell culture.
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Develop RNA purification, characterization, and analytical methods to generate therapeutic grade material for in vitro and in vivo studies. Our team interacts with multidisciplinary groups across AbbVie focused on developing therapies for Virology, Immunology, Neurology, Ophthalmology and Oncology diseases.
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The candidate's main responsibilities will include: a) novel assay development, b) in-vitro T cell circuit design and validation, c) establishment of in-vivo tumor models, d) compiling pre-clinical results to support the designation of clinical vector design, and e) leading the in-vitro and in-vivo pharmacology characterization of therapeutic product candidates in collaboration with a process development team towards an IND filling.
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