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The position is accountable for designing and implementing scientific strategy across Incyte's research pipeline of programs targeting Inflammation, Autoimmunity and Immuno-Oncology. Overview Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity.
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The Associate Director, Precision Medicine Strategy Lead will independently oversee the development and execution of biomarker strategies across Oncology/ Immuno-Oncology. Additionally, 10+ years’ experience participating effectively on cross-disciplinary teams in pharmaceutical or biotech industry, with a minimum of 2-3 years in oncology clinical drug development.
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Experience in gene expression and signaling pathway analyses as well as mechanistic studies in immuno-oncology and immunology research a plus. Responsible for the development and execution of in vitro or ex vivo assays to characterize receptor binding, signaling, cell activation/suppression, and other functional readouts using a variety of techniques including flow cytometry-based assays, ELISA, and reporter assays.
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With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of hematological cancers, we are motivated by a dedication to the scientific discovery and collaboration that will one day help eliminate cancer as a cause of death.
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Experience in Translational Medicine with clinical-stage oncology/ immuno-oncology drug development is highly desirable. You will be a highly motivated scientist, dedicated to biomarker discovery, clinical biomarker development, implementation, and interpretation to help advance our oncology pipeline.
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At least 10-15 years of experience in the pharmaceutical/biotechnology industry in oncology clinical development; immuno-oncology (I/O) experience is highly preferable. The successful candidate will have the ability to bring creative/innovative clinical designs to define and apply the most effective approach across Marengo's R&D pipeline while working closely with drug development teams (e.g., drug discovery, immunology, clinical development, clinical operations, regulatory, safety, and pharmacovigilance.
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The successful candidate should have strong expertise in immuno-oncology and will be focused on focus on the development of fit-for-purpose CMC assays using flow cytometry and cell-based immunoassays, to characterize engineered TCR-T cell drug substance and drug product.
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Leap Therapeutics (Nasdaq: LPTX) is focused on developing targeted and immuno-oncology therapeutics. Ability to lead and manage a matrixed Program team and coordinate cross-functional aspects of drug development (e.g., medical, regulatory, clin ops, safety, biometrics, quality, supply, etc.
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By harnessing the power of four scientific platforms - Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, and Antibody Drug Conjugates - and by championing the development of personalized combinations, AstraZeneca has the vision to redefine cancer treatment and one day eliminate cancer as a cause of death.
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3 years as a Clinical Trial Scientist or comparable role Strong familiarization with Good Clinical Practice (GCP) and drug development processes, ideally Phase 1 - 3; ideally paired with experience in Oncology / Immuno-Oncology Good knowledge of set-up, organization and execution of global clinical studies in a pharmaceutical company or contract research organization (CRO), or comparable experience within academic research institution.
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Boehringer Ingelheim Executive Director, Oncology Translational Medicine and Clinical Pharmacology- Immuno-Oncology Ridgefield , Connecticut Apply Now As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development, and delivery of our products to our patients and customers.
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Our preclinical pipeline extends beyond to biologics against novel immuno-oncology targets, antibody-drug conjugates, bispecific and trispecific antibodies, and small molecules expected to reach the clinic in 6-24 months, underscoring our bench-to-bedside approach.
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At least 7 years of drug development experience specifically in human drug development at a biotech/pharmaceutical company or the equivalent experience at an academic clinical research (NCI, NIH, Academic Research groups etc.
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They will design, develop, communicate at senior levels and operationally implement Precision Medicine strategies to support select, key programs in early and late stage drug development.
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While maintaining its stronghold as a generics powerhouse, our client is expanding its pipeline to concentrate on vital therapeutic areas such as neuroscience, immunology, and immuno-oncology.
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