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The role requires demonstrated expertise in histopathology, microscopy, tissue-based assay development (IHC/ISH/mIF), analysis, and data interpretation with an ability to integrate scientific and disease specific contexts.
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Experience with IHC/IF assay development using automated IHC platforms (Ventana, BondRx or similar) is a plus. IHC or histology background required. Experience with IHC/IF assay development using automated IHC platforms (Ventana, BondRx or similar) is a plus.
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The schedule for this position will be:3rd shift, Monday – Friday 9:00 pm – 5:30 amThis position will be performing special stains, IHC stains, and will be using the Ventana Ultra and Benchmark special staining instrumentation.
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The UM-IHC, located in North Bethesda, MD, is a collaborative effort of the University of Maryland Baltimore, the University of Maryland College Park, and the University of Maryland Medical System, funded with initial grants from the State of Maryland's MPower initiative and Montgomery County, MD.Key foci of the Institute include population health, clinical trial innovation, data analytics, therapeutic target discovery, and education and training.
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Experience with ELISA/ WB, IHC/ Immunofluorescence and microscopy is a plus. Experience in therapeutic drug discovery, gene therapy or RNA therapeutics. Experience with ELISA/ WB, IHC/ Immunofluorescence and microscopy is a plus.
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Your day-to-day will involve:Engaging in dynamic discussion laboratory personnel in our US and European locations to guide them in developing IHC/IF single-plex/multi-plex assays and in situ hybridization (ISH)Partnering closely with our digital pathology team and data scientists to develop and verify digital image analysis algorithms and results from image analysis projects.
$170,625 - $284,375 a yearFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Demonstrated leadership in translational sciences (employing pharmacodynamic, predictive and exploratory biomarkers) and experience with development of assays including ligand binding assays, IHC/IF, gene expression profiling, flow cytometry.
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These technologists perform IHC and DIF procedures, Enzyme Histochemistry, grossing of small biopsies, and are involved in laboratory education. These technologists perform IHC and DIF procedures, Enzyme Histochemistry, grossing of small biopsies, and are involved in laboratory education.
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Your laboratory benchwork contributions will focus on supporting the IHC team with routine FFPE sample creation and histology slide sectioning and cataloging. Experience with cell-based assays including flow cytometry, ELISA, and/or western blotting is desired.
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Develop novel techniques for Multiplexed IHC analysis of biomarkers on tissue samples. Develop multiplexed IHC based techniques utilizing FFPE surgical specimens, core needle biopsies and smears from different tumor types to biomarkers analysis.
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Highly familiar with standard analytics equipment and procedures including, but not limited to Flow cytometry, ELISA, DNA/RNA analysis, cell-based and screening assays, protein analysis, sterility, mycoplasma, endotoxin, cell-counting, qPCR, ddPCR, IHC/pathology.
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Develop, qualify, and validate (as appropriate) bioanalytical assays (expressions assays including mRNA and protein [ELISA/IHC], anti-AAV capsid nAb, CTL IFN-γ ELISPOT, IgG/IgM, biodistribution and shedding) for all programs and define science-driven, phase appropriate, and risk-based analytical development strategies to support the development candidate during discovery through preclinical evaluation (including GLP) and clinical development advancement.
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Biocare is the market leader in simultaneous Multiplex IHC tests which provide increased confidence at critical diagnostic decision points, impacting patient therapy while accelerating turnaround time.
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SummaryUnder the supervision of the Histology Supervisor, performs a variety of duties involved in the registration, accessioning, identification and processing of Pathology specimens according to established methods and procedures to include staining, storage of specimens, operation of equipment used in the preparation of liquid based GYN/Non-GYN specimens, and operation of equipment used in the H-E/IHC staining of surgical specimens.
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Preferred knowledge of cytology, including GYN and Non –GYN specimens and Pap Smear preparation and reading is suggested, IHC and special stains, Bone Marrow processing and Transcription. The primary responsibility for this position will include one of the following (or a combination of all) areas in the Clinical Laboratory:· Microbiology: includes the subspecialties of Bacteriology, Mycology, Mycobacteriology, Virology, Parasitology and Molecular Microbiology.
$43.89 - $61.44 an hourFull-timeExpandApply NowActive JobUpdated 5 days ago
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