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Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases.
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Manufacturing Associate 4, SME or Lead (Gene Therapy Program) The laboratory of Dr. James Wilson, in the Gene Therapy Program, has been a leader in the development of innovative vector technology for close to three decades.
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Lead commercial assessments of potential therapeutic targets and programs; provides analyses and decision making frameworks to guide the company's portfolio activities in maximizing NAV technology and advancing subsequent gene therapy pipeline.
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R&D Project Management within the global Cell&Gene Therapy R&D Program Management team you will support our global Program Managers and the Portfolio Lead with coordination of translational and early clinical programs and respective scientific platform technology projects.
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The individual will devise, troubleshoot, and validate cell-based assays to assess the critical quality attributes of AAV gene therapy products including potency and infectivity. The incumbent will be involved in the design and execution of novel cell-based assays, writing technical reports, supporting method validation and qualification activities performed in the Sarepta Gene Therapy QC laboratories and/or at contract testing laboratories.
$96,000 - $120,000Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Deep expertise in a particular therapeutic area or modality (e.g. gene therapy) is a benefit, but not required. Articulate and communicate non-clinical safety strategies and provide development plans for multiple drug modalities including but not limited to small molecules, biologics, ADCs, and/or cell and gene therapies, across various therapeutic areas including but not limited to oncology, neuroscience, and immunology.
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The primary focus of this talented individual is to lead part of the process development/engineering scale-up activities for drug substance processes for one of our key cell and gene therapy assets.
Full-timeExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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Demonstrated competency, experience, and knowledge with new therapeutic modalities including AAV gene therapy. Champion the advancement of the AAV viral vector production and purification platform through creative solutions including technology scouting and DoE experiments to accelerate gene therapy programs.
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This role will be the Biostatistics lead for a Therapeutic Area comprising of two or three gene therapy clinical programs in rare diseases. This role will be the Biostatistics lead for a Therapeutic Area comprising of two or three gene therapy clinical programs in rare diseases.
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SCiAN’s therapeutic expertise includes immuno-oncology, gene therapy, CNS, infectious disease, autoimmune diseases and diabetes. Therapeutic experience in Oncology, CNS, Medical Affairs, Immunology or orphan drug indications strongly desired.
ExpandApply NowActive JobUpdated 15 days ago - UpvoteDownvoteShare Job
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Experience in therapeutic area such as oncology, immunotherapy, or gene therapy is highly desirable. They specialize in the research, development, and commercialization of novel gene therapy approaches aimed at treating a wide range of genetic disorders, rare diseases, and other debilitating conditions.
ExpandApply NowActive JobUpdated 10 days ago - UpvoteDownvoteShare Job
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Lead and manage a group of ~80 scientists responsible for conceiving and developing new gene therapeutic concepts, AAV vector design and development, and translational research to advance the concepts toward clinical testing Partner closely with members of the Rare Disease Unit (RDU) and members of AstraZeneca’s Discovery Sciences genomic medicine group to identify, implement and progress new gene therapy projects.
Full-timeExpandApply NowActive JobUpdated 1 month ago - UpvoteDownvoteShare Job
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Have knowledge of the execution and implementation of the bioanalytics associated with RNA or AAV gene therapy with gene editing preferred. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies.
Full-timeExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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The initial effort will be towards a first-in-class gene therapy program for age-related macular degeneration, a prevalent and blinding condition, and provide strategic, clinical, and scientific support through all phases of clinical development.
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The ElevateBio ecosystem combines multiple R&D technology platforms – including Life Edit, a next-generation, full-spectrum gene editing platform; comprehensive cell engineering technologies; and an expanded viral and non-viral therapeutic delivery platform – with BaseCamp, its end-to-end genetic medicine cGMP manufacturing and process development business, to accelerate the discovery and development of advanced therapeutics.
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