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Must have hands on experience in RNA nanoparticle formulation, purification, and characterization assays in academia or direct experience in a biotechnology company. Work closely with RNA production, LNP/RNP formulation, and in vitro and in vivo team members.
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The successful candidate will have a strong hands-on background in wet lab biology to support nanomedicine-related research including but not limiting to nanoparticle formulation, flow cytometry, molecular endpoints, bioconjugate chemistry, in vitro assays, gel-based characterization and cell-based assays.
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Hands on experience in polymer nanoparticles formulation preparation with protein/peptides and small molecule APIs encapsulation will be an asset. Carry-out hands-on activities following detailed experiment/assay protocols to complete the formulation/characterization runs in an efficient, safe, and correct manner.
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Your 5-10 years of hands-on experience formulating, scaling, and troubleshooting cleansers, emulsions and hot pours are the source of your credibility and will assist you in mentoring more junior formulators and lab technicians as we develop their technical competence.
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Creative problem solver with hands on experience in problem framing, qualitative & quantitative research, running product experiments, hypothesis testing and prototyping to launch products at the intersection of Human, Technology and Business dimensions.
$120,550 - $230,400 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Under the direction of the Manufacturing Supervisor or Team Lead, the Manufacturing Technician will work hands on, in their designated production suite, with a variety of manufacturing production equipment and technologies.
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This role will require the candidate to be both willing and able to perform necessary hands-on formulation, synthesis, characterization, sample prep, etc. Excellent knowledge of and hands on experience with NMR, GPC, FT-IR as well as interpretation of the respective data.
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Hands on work will be required in small and large scale including, but not limited to, upstream, downstream, conjugation, formulation and lyophilization processes as needed. Perform shake flask culture, cell banking, fermentation, harvest clarification, normal and tangential flow filtration, homogenization, conjugation, chromatography techniques and/or formulation as needed.
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Extensive hands-on experience with Molecular Biology (as PCR, qRT-PCR, ddPCR, DNA/RNA and protein preparation), Cloning, mammalian cell culture and transfection is required. You will work with an outstanding team of molecular biologists, protein engineers, gene-editing experts, pharmacologists, organic chemists, and formulation scientists to create new and effective approaches to deliver our innovative platforms into preclinical mouse models.
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Must have hands-on experience with HPLC, UPLC equipment and methods. Must have hands-on experience with plate-based assays. Design and implement experiments for the formulation and characterization of polymeric, liposomal, lipid and other nanoparticles for in vivo drug delivery.
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Conduct hands-on experimental work which includes:Adhesive formulation, application and curingFilm preparation and surface treatmentsFilm to film lamination experimentsFilm and laminates characterizationFilms and Laminates forming experiments.
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Hands on experience with protein sample preparations, aseptic operations, and stability studies are essential. Lead effort on high concentration formulation development both in vials and in prefilled syringes for all Lundbeck protein candidates.
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Who You Are: Currently enrolled in a Masters or a PhD Program in Pharmaceutical Sciences, Chemical Engineering, Chemistry Senior in undergraduate program in Pharmacy, Chemical Engineering, Chemistry or Biology Previous in lab/hands on experience Able to commute to Billerica, MA and work 100% onsite Skills:Laboratory/Sciences Experience:Entry Level responsibilities: Targeted mRNA delivery (TMD) is seeking a self-starter, highly motivated and eager to learn co-op in their LNP Formulations group.
$28 - $30 an hourFull-timeExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Optimization algorithms formulation & research: Tackle complex scientific & operations research problems by researching published academic literature, surveying industry techniques & intuition, and executing hands-on experimental testing & modeling.
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We focus on bringing client drug compounds from discovery to the clinic with services that include analytical development, pre-formulation testing, formulation development, GMP manufacturing and stability storage and testing as well as Clinical Supply Services.
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