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The Director of Upstream Process Development - Microbial Platform will oversee the development of all upstream technical activities (including microbial strain generation, fermentation/upstream process development) throughout the clinical development and commercialization of recombinant drug substance for Lilly's biologics portfolio.
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Experience with fermentation and bioreactor operation a plus. Summary: Vaxcyte is looking for an energetic and talented individual to join Vaxcyte’s Vaccine Product Development organization as a Senior Associate Scientist of Upstream Development within the Protein Development and Clinical Manufacturing group.
$107,000 - $123,000 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Industry experience with early discovery and development of vaccines including optimization of upstream/downstream technologies that include benchtop fermentation, adjuvant selection and optimization, familiarity with in-process and potency assay design and development.
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Experience with commissioning and qualification of biotech process equipment (upstream or downstream or both), such as some, but not all, of the following: fermentation, bioreactors, downstream purification processes (chromatography, TFF, UF) is required.
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Perform shake flask culture, cell banking, fermentation, harvest clarification, normal and tangential flow filtration, homogenization, conjugation, chromatography techniques and/or formulation as needed.
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About the Opportunity: The Senior Fermentation Scientist will join our Upstream Bioprocess Development team and will be responsible for the design & execution of fermentation experiments for development of new bioprocesses.
$140,000 - $150,000 a yearFull-timeExpandUpdated Yesterday - UpvoteDownvoteShare Job
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Will be a technical expert in microbial strain and fermentation process development and oversee the development of upstream technical activities (including microbial strain generation, and fermentation/upstream process development) through the clinical development.
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This position leads a group responsible for upstream process development to support pipeline projects from pre-clinical to commercial stage. AstraZeneca is seeking an initiative-taking leader for biologics process development with a focus on upstream operations.
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7 positions: 2 positions will support upstream fermentation/cell culture. Will have a fundamental knowledge of fermentation and cell culture, protein chemistry and purification, analytical techniques and/or laboratory operations.
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Bachelor’s degree in a Scientific, Engineering or Biotech field with 4 years’ experience with upstream (fermentation/bioreactor) biologic production processes under GMP compliance. HS Diploma or Associate’s Degree with 5– 6 years’ experience with upstream (fermentation/bioreactor) biologic production processes under GMP compliance.
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The successful candidate will have practical laboratory fermentation experience in executing, supporting, or developing upstream processes related to biotechnology, biopharmaceuticals, or vaccine industries.
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The Sr. Scientist of Upstream Process Development will oversee the development of all upstream technical activities (including microbial strain generation, fermentation/upstream process development) through the clinical development of recombinant norovirus vaccine program.
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Upstream processes include tissue culture, cell bioreactors, fermentation, virus propagation, cell and virus bank production, and buffer/media preparation. The position will be responsible for performing upstream and downstream bioprocessing procedures to support the commercial manufacturing of native antigens, recombinant proteins, antibodies, and blockers.
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Strong knowledge and experience in mammalian cell culture / bacterial fermentation / viral vector production operations (aseptic operations, cell biology, biochemistry, analytical techniques, bioreactor operations.
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Upstream process development and regulatory submission experience for diverse types of biologics and new modalities in an industry setting. The Bioprocess Research and Development team has an exciting opportunity for an innovative scientist, technical expert in microbial strain and fermentation process development to join our process development organization.
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