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The successful candidate will become a key member of our in vitro biology core group, which is an essential component in the company's drug discovery operation. Experience in cell biology techniques, including gene and protein expression analysis, assay development and optimization, flow cytometry, and multiplexing to support lead discovery, target validation, and hit optimization.
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Drive, in partnership with other oncology and Novartis Biomedical Research functional leaders, new areas of scientific investment in drug discovery including novel targets, tumor targeting modalities, linker payloads and external collaborations and partnerships.
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As the first company to fully harness the power of RNA technology for human therapeutics, Ionis' platform continues to revolutionize drug discovery and transform lives for patients with unmet needs.
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Doctorate Degree - Doctorate (MD, PhD, VMD, or DDS) in in biomedical sciences, pharmacology, or an area directly related to field of research specialization, with demonstrable laboratory experience in drug discovery and natural products research, and in vivo mouse models for antitumor efficacy and pharmacology within the past 4 years.
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The Senior Director of Chemistry is an accomplished medicinal chemistry professional with a proven track records of success in small molecule drug discovery. Deep expertise in leading small molecule drug discovery programs in a biotechnology or pharmaceutical company setting.
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5+ years of experience in academia, biotechnology, or pharma industry with a primary focus on understanding AAV biology and discovery and preclinical development of gene therapy products. With accelerated review underway in the United States and Europe for our Hemophilia A drug, a second gene therapy program entering the clinic for PKU patients, and a third program in late research for Hereditary Angioedema, BioMarin continues to pioneer innovative approaches to treating rare diseases.
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Engage in computational biology and target identification initiatives to support drug discovery efforts. They are a leading biotechnology company working on advancing their computational platform within the Discovery Biology team.
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8+ years of experience in oncology drug discovery, precision medicine, or translational science in biotech or pharmaceutical industry. Working across discovery, preclinical and clinical development teams, the candidate will provide scientific leadership and expertise in areas of biomarker discovery, translational studies, and biomarker data analysis to advance the understanding of Synnovation’s precision medicines and generate hypotheses to improve clinical outcomes.
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The primary purpose of this computational Data Scientist is to develop data science tools and predictive algorithms as part of the development of our flagship platform A3D3a: Adaptive, AI-augmented, Drug Discovery and Development.
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Understanding of healthcare-specific challenges, such as clinical trials, drug discovery, and healthcare quality improvement. Experience with sentiment analysis for NLP. Skilled in deploying and maintaining model Microservices and data pipelines for deep learning models.
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You'll have experience in cell and immuno-oncology based assays, including flow cytometric and plate-based methods for preclinical drug discovery & functional validation. You will have (extensive) knowledge and practical experience in immuno-oncology/ T-cell biology from an industrial drug discovery background, encompassing from early stage discovery to pre-clinical validations.
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Successful candidates will demonstrate potential to develop a prominent and innovative research program that complements the University’s research strengths in host-pathogen interactions, immunity and host defense, virology, mycology, genomics, drug discovery, translational research, and clinical trials.
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This novel drug platform builds on the discovery that modified mRNA can direct the body’s cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells.
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Develops and leads the global Haematology Discovery R&D strategy to ensure the delivery of a sustainable portfolio of drug discovery programs. champion a working environment that promotes science and encourages innovation in drug discovery.
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Candidate should be business orientated, having managed resources and budgets with proven record of leading projects trough successful transition from Discovery to Early Development and advancement of projects through preclinical and clinical development to Phase 2b within the therapeutic area.
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