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For various levels you must have the following: Associate Process Characterization & Technology Scientist: 0-2 years of experience Process Characterization & Technology Scientist: 2 years of experience Sr Process Characterization & Technology Scientist: 5 years of experience Experience with bioreactor, cell culture, microbial fermentation, and cGxP is preferred.
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To help us meet our mission LOTTE BIOLOGICS is in need of a Scientist, Manufacturing Technology to support upstream cell culture and downstream purification commercial manufacture of biopharmaceutical drug substance produced at the LOTTE BIOLOGICS Syracuse facility.
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Experience with molecular biology, protein expression, mammalian cell culture, protein purification, biochemical engineering, or protein analytical technologies. BPR&D includes three lab-facing technical functional areas: Process Cell Sciences (PCS), Upstream and Downstream Process Development & Engineering.
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The candidate will have opportunities to work in cell culture development and purification development to become a well-rounded process development scientist with experience in upstream and downstream.
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1-5 years experience in viral vector/cell therapy (or biopharmaceutical) based GMP manufacturing operations including direct experience in cell culture, cell selection, recovery, purification, and/or aseptic fill/finish.
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Just - Evotec Biologics' Bioreactor Process Development group is seeking an enthusiastic and hardworking team member who is passionate about expanding worldwide access to biotherapeutics through the advancement of continuous bioprocessing technology and mammalian cell culture processes.
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As part of the MSAT group, you will have opportunities to work on and specialize in expertise of Upstream (US) Cell Culture and/or Downstream (DS) Purification. Bionova is a rapidly growing, biologics CDMO focused on developing and manufacturing recombinant protein products using mammalian cell culture processes.
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Knowledge of cell-line development for protein expression in mammalian systems and suspension cell culture. Knowledge of recombinant protein expression, metabolic pathways, biochemistry, and cell culture.
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Hands-on expertise in engineering and operating shake flasks, small-scale bioreactors, bench-top bioreactors including ambr, pilot scale reactors and stainless-steel bioreactors used for mammalian cell culture processes.
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In this role, the successful candidate will work closely with highly motivated team of Scientists and Engineers in the Upstream Process Development area and contribute to CMC development of our company's pipeline, playing an active role in design, development and optimization of cell culture processes and transfer processes to clinical and commercial manufacturing sites.
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Functioning as a key member of the process development team through executing lab-scale process development, in-process assay support, and process scale-up or scale-down of cell culture/fermentation (upstream) and/or purification (downstream) process unit operations.
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The candidate may also be involved in downstream purifications, specifically with ProteinA purifications from small scale cell culture. RESPONSIBILITIES Laboratory Scale Cell Culture experience, ProteinA purification experience, spectroscopy such as FTIR or UV, coursework in analytical chemistry, physical chemistry, and statistics The candidate will be responsible for operating lab-scale bioreactors, including daily sampling activities, bioreactor assembly, and harvest of bioreactors.
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The UC Irvine Department of Otolaryngology seeks a part-time or full-time project scientist with experience in CRISPR to work on inner ear therapeutics in cell culture and animals.
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The position will require a high degree of autonomy in the discipline and work with colleagues in cell culture, bacteriology, virology, formulation, and bioanalytical science. The role of the downstream bioprocess scientist will provide technical support for complex equipment and Biological and Biopharmaceutical processes.
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Perform cell-based assay to evaluate gene editing efficiency of candidate's formulations, and maintain mammalian cell culture for research projects, and downstream cellular DNA extraction and NGS or sanger sequencing assays for data analysis.
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