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Manufacturing cGMP production activities include solution preparation, master/working cell bank production, upstream cell culture, downstream protein purification, mRNA and molecular therapeutics production, and small-scale fill/finish.
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Performs basic Downstream purification and mRNA production activities, such as in-vitro transcription (IVT) reactions, chromatography, tangential flow filtration (TFF), viral filtration, and column packing and qualification.
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Upstream processes include tissue culture, cell bioreactors, fermentation, virus propagation, cell and virus bank production, and buffer/media preparation. Downstream unit operations include harvest, clarification, chromatography, centrifugation, TFF (UF/DF), filtration, formulation, and fill-finish.
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Technician - Biomanufacturing, Downstream/mRNA. Accurately follows manufacturing Batch Production Records (BPRs) and Standard Operating Procedures (SOPs) in accordance with current Good Manufacturing Practices (cGMPs) and with a focus on "right first time" execution.
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Scheduling of Natural Gas wellhead and pipeline volumes to ensure accurate and complete accounting of production and deliveries to downstream pipelines while minimizing shipper imbalances on gathering systems and Operating Balance Agreement imbalances on interstate pipelines.
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Operate and maintain the Downstream pilot plant production line in the San Carlos facility. A fast-growing vaccine company is looking to a hire an energetic and talented individual to manage and operate the downstream pilot-scale operations in our San Carlos pilot plant facility within the protein process development and manufacturing group.
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Hands on experience with downstream analysis techniques including, but not limited to, HPLC, SDS-PAGE, Western Blots, ELISA, and ddPCR. The ideal candidate will have a blend of broad experience that spans chemistry, biochemistry, proteomics, and biopharmaceutical production.
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The Machinist is responsible for tools and equipment to maintain and build production tooling by making downstream tooling, dies, and rebuilding of downstream related equipment needed to support the manufacturing and distribution needs of the company (with a foremost priority of safety.
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As a Associate Scientist I, Plasmid Development & GMP Manufacturing (position title to be determined based upon experience)you will be responsible for the production and purification of plasmid DNA in compliance with current Good Manufacturing Practices (cGMP) regulations.
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The Sr. Associate Scientist/Scientist is responsible for the development and optimization of the cell line development platform for production of biotherapeutics. Work closely with other members of Cell Science team and downstream Process Development team to develop and execute multiple projects under tight timelines.
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Downstream Days: Front: Sunday – Tuesday (SWD) Pivot Day: Every other Wednesday. Downstream Manufacturing (DM): Responsibilities include the operation and cleaning of fixed tank systems, the operation and cleaning of filtration systems, large-scale buffer preparation, and the operation of column chromatography systems; perform dispensing of components; handle and aliquot hazardous materials.
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The Downstream segment focuses on refining, logistics, power generation, and the marketing of crude oil, petroleum and petrochemical products, and related services to international and domestic customers.
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Coordinate with internal and external customers on daily production requirements and socialize midstream/downstream provider capacity changes. Work closely with INEOS Energy Trading to evaluate downstream markets to ensure highest, optimal value for US Onshore crude.
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As a Manufacturing Associate, under the direction of the Associate Director or Director of Manufacturing, you will be responsible for executing either upstream or downstream operations for the production and purification of viral-based vectors for clinical use.
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The Upstream segment includes crude oil, natural gas and natural gas liquids exploration, field development, and production. The Global Manufacturing Excellence organization will be the center of excellence in Global Manufacturing under Downstream business line within This Company for Digital transformation, Artificial Intelligence technologies and data science.
ExpandApply NowActive JobUpdated 3 days ago
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