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As a Research Associate II in DSP (Downstream Processing), you'll dive into the intricate world of impurity fate, product stability, and degradation mechanisms. Hands on experience with bench scale filtration, evaporation and crystallization.
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Processing experience includes but not limited to: Chromatography, writing/using unicorn methods, Tangential Flow Filtration, Aseptic processing, bulk drug substance and drug product operations.
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Drive the CMC elements related to bioconjugation throughout the product life cycle using technical expertise in conjugation chemistry and downstream unit operations including tangential flow filtration, dead-end filtration, and protein chromatography.
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The Head of Downstream will work closely with the management team and MSAT (Material Science & Technology) teams to ensure the effective and efficient tech transfer of products and processes to the MFG11 Facility.
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Operation of bioreactors/fermenters, Tangential flow filtration (TFF), centrifugation, chromatography, and ultra-purification processes. Fundamental understanding of bioreactors/fermenters or downstream purification techniques.
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The Director, Manufacturing Operations will oversee, lead Upstream & Downstream operations; manage process/cleaning validation, scale up & technology transfer; direct personnel for efficient use of equipment in accordance with the production plan; as well as be responsible for the costing & budgeting for the products manufactured by Kashiv Biosciences LLC.
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Independently executes complex unit operations including but not limited to chromatography operations, tangential flow filtration, various filtration methods, and process monitoring. Executes and coordinates unit operations in Downstream manufacturing as assigned related to the manufacturing of bulk drug substance in a multi-product facility.
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Performing downstream operations such as normal flow filtration, tangential flow filtration, homogenization, lyophilization, chromatography, and centrifugation. Performing downstream operations such as normal flow filtration, tangential flow filtration, homogenization, lyophilization, chromatography, and centrifugation.
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Passionate about protein purification (including chromatography, bioprocess filtration, scale up, and optimization) and harnessing the power of enzymes to solve challenging real-world problems in the healthcare industry.
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Hands-on experience developing, executing, and optimizing protein purification processes, including chromatography, TFF, and bioprocess filtration unit operations. Leading development, hands-on execution, and optimization of protein purification processes including primary recovery unit operations (centrifugation, homogenization, flocculation, tangential-flow filtration (TFF), and depth filtration), chromatography (ion-exchange, affinity, hydrophobic interaction), and pre-formulation (TFF, dialysis.
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Possesses working knowledge in downstream processing for vaccine production, e.g. Lyophilization, Tangential Flow Filtration, Centrifugation, Emulsification, Filling, etc. Possesses working knowledge in downstream processing for vaccine production, e.g. Lyophilization, Tangential Flow Filtration, Centrifugation, Emulsification, Filling, etc.
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We are seeking a Downstream Technician II responsible for expanding our lab-scale recovery capabilities to remove or recover micro-organisms and bioactives from broth generated at our Fermentation Research Facility in Wilmington, DE.
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The candidate will use mammalian cell culture techniques as well as purification techniques (centrifugation, chromatography, ultrafiltration, and nanofiltration) processes. At Zoetis in Lincoln, NE, we manufacture high quality medicines for dogs, cats, and livestock.
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The Downstream Manufacturing Associate or Technician will actively contribute to the manufacturing and technology transfer projects at the Bionova Scientific Fremont location. Execute, with oversight of qualified staff, complex unit operations including but not limited to chromatography, TFF, depth filtration, virus filtration, and buffer preparation in GMP manufacturing suites.
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Hands-on support for downstream purification steps such as chromatography, harvest clarification and normal flow filtration. Reporting to the Director of internal Downstream development and manufacturing, focusing on protein purification, disposable technologies and compliance for early-stage clinical production.
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